2767066-84-0
Chemical Structure
5-epi-Arvestonate A
- CAS No.: 2767066-84-0
- Formula:C16H26O5
- Molecular Weight:298.37
IUPAC Name: 2-bromo-6,6-dimethyl-5,6-dihydro-4H-pyrrolo[3,4-d]thiazol-4-one
InChIKey: PTQLNNHOWVIIJF-BEKRQIFDSA-N
SMILES: C[C@@]1([C@@H](CCC([C@]1([C@H]2O)O)=C)O)CC[C@@]2([H])[C@@H](C)C(OC)=O
Biological Activity: 5-epi-Arvestonate A is a sesquiterpenoid isolated from the whole plants of Seriphidium transiliense. 5-epi-Arvestonate A promotes melanogenic production by activating the transcription of microphthalmia-associated transcription factor (MITF) and tyrosinase family genes. 5-epi-Arvestonate A inhibits the expression of IFN-γ-chemokine through the JAK/STAT signaling pathway in immortalized human keratinocyte (HaCaT) cells[1].
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5-epi-Arvestonate A | 5-epi-Arvestonate A is a sesquiterpenoid isolated from the whole plants of Seriphidium transiliense. 5-epi-Arvestonate A promotes melanogenic production by activating the transcription of microphthalmia-associated transcription factor (MITF) and tyrosinase family genes. 5-epi-Arvestonate A inhibits the expression of IFN-γ-chemokine through the JAK/STAT signaling pathway in immortalized human keratinocyte (HaCaT) cells. | |||||||||||||||||||||
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Keywords