31272-50-1
Chemical Structure
meso-Zeaxanthin
Synonym(s): (3R,3′S)-Zeaxanthin
- CAS No.: 31272-50-1
- Formula:C40H56O2
- Molecular Weight:568.87
InChIKey: JKQXZKUSFCKOGQ-YOPUJPICSA-N
SMILES: CC1(C)C(/C=C/C(C)=C/C=C/C(C)=C/C=C/C=C(C)/C=C/C=C(C)/C=C/C2=C(C)C[C@@H](O)CC2(C)C)=C(C)C[C@H](O)C1
Biological Activity: meso-Zeaxanthin ((3R,3′S)-Zeaxanthin) is an orally active xanthophyll carotenoid. meso-Zeaxanthin inhibits CYP1A1, CYP1A2, CYP2B1/2, COX-2, TNF-α and iNOS, and enhances the activities of Uridine diphosphate glucuronosyltransferase and Glutathione-S-transferase. meso-Zeaxanthin quenches oxygen free radicals. meso-Zeaxanthin filters short-wavelength blue light, alleviates oxidative damage and visual abnormalities. meso-Zeaxanthin reduces tumor incidence, prolongs tumor latency and survival rate of tumor-bearing mice, and inhibits paw edema. meso-Zeaxanthin can be used in research related to sarcoma and age-related macular degeneration[1][2][3][4].
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meso-Zeaxanthin | 93.09% | meso-Zeaxanthin ((3R,3′S)-Zeaxanthin) is an orally active xanthophyll carotenoid. meso-Zeaxanthin inhibits CYP1A1, CYP1A2, CYP2B1/2, COX-2, TNF-α and iNOS, and enhances the activities of Uridine diphosphate glucuronosyltransferase and Glutathione-S-transferase. meso-Zeaxanthin quenches oxygen free radicals. meso-Zeaxanthin filters short-wavelength blue light, alleviates oxidative damage and visual abnormalities. meso-Zeaxanthin reduces tumor incidence, prolongs tumor latency and survival rate of tumor-bearing mice, and inhibits paw edema. meso-Zeaxanthin can be used in research related to sarcoma and age-related macular degeneration. | ||||||||||||||||||||
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- [1]. Firdous AP, et al. Anticarcinogenic activity of meso-zeaxanthin in rodents and its possible mechanism of action. Nutrition and cancer. 2013;65(6):850-6.
- [2]. Firdous AP, et al. Anti-inflammatory potential of carotenoid meso-zeaxanthin and its mode of action. Pharmaceutical biology. 2015 Jul;53(7):961-7.
- [3]. Nolan JM, et al. What is meso-zeaxanthin, and where does it come from?. Eye (London, England). 2013 Aug;27(8):899-905. [Content Brief]
- [4]. Bernstein PS, et al. Lutein, zeaxanthin, and meso-zeaxanthin: The basic and clinical science underlying carotenoid-based nutritional interventions against ocular disease. Progress in retinal and eye research. 2016 Jan;50:34-66.
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