Fgb - fibrinogen beta chain Gene

Also Known as Ab1-181; Ab1-216; Ac1-581

Species: Rattus norvegicus

Gene Type: protein coding
Gene ID: 24366

Summary

Predicted to enable chaperone binding activity; signaling receptor binding activity; and structural molecule activity. Predicted to contribute to cell adhesion molecule binding activity. Involved in cellular response to interleukin-1 and cellular response to Leptin stimulus. Located in blood microparticle and cytoplasm. Biomarker of pancreatitis and pulmonary embolism. Human ortholog(s) of this gene implicated in cardiovascular system disease (multiple); congenital afibrinogenemia; and end stage renal disease. Orthologous to human FGB (fibrinogen beta chain). [provided by Alliance of Genome Resources, Apr 2022]

Fgb Products (1)

mRNA Protein Name
NM_020071.2 NP_064456.2 fibrinogen beta chain precursor
Biological Process GO Annotation Evidence Références Source
involved in cellular response to interleukin-1 IEP
IEP: Inferred from expression pattern
17521427 RGD
involved in cellular response to leptin stimulus IEP
IEP: Inferred from expression pattern
17521427 RGD
Cellular Component GO Annotation Evidence Références Source
located in blood microparticle IDA
IDA: Inferred from direct assay
22014850 RGD
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

fibrinogen beta chain

  • beta-fibrinogen

  • fibrinogen, B beta polypeptide

  • fibrinogen, beta polypeptide

  • liver regeneration-related protein LRRG036/LRRG043/LRRG189

Orthologs Information

Species Symbol Source ID
Homo sapiens Fgb NCBI NCBI:2244