Fam107a - family with sequence similarity 107, member A Gene
Also Known as DRR1
Species: Mus musculus
Summary
Predicted to enable actin binding activity. Involved in several processes, including actin filament organization; cellular response to glucocorticoid stimulus; and negative regulation of long-term synaptic potentiation. Located in actin cytoskeleton; neuron projection; and synapse. Is expressed in diencephalon ventricular layer; hypothalamus ventricular layer; inner ear; and olfactory epithelium. Orthologous to human FAM107A (family with sequence similarity 107 member A). [provided by Alliance of Genome Resources, Apr 2022]
Fam107a Products (4)
| mRNA | Protein | Name |
|---|---|---|
| NM_001360337.1 | NP_001347266.1 | actin-associated protein FAM107A isoform 1 |
| NM_001360338.1 | NP_001347267.1 | actin-associated protein FAM107A isoform 1 |
| NM_001360339.1 | NP_001347268.1 | actin-associated protein FAM107A isoform 2 |
| NM_183187.4 | NP_899010.1 | actin-associated protein FAM107A isoform 1 |
| Molecular Function GO Annotation | Evidence | Références | Source |
|---|---|---|---|
| enables protein binding |
IPI
IPI: Inferred from physical interaction
|
21969592 | MGI |
| Biological Process GO Annotation | Evidence | Références | Source |
|---|---|---|---|
| involved in actin filament bundle assembly |
IMP
IMP: Inferred from mutant phenotype
|
21969592 | MGI |
| involved in actin filament polymerization |
IMP
IMP: Inferred from mutant phenotype
|
21969592 | MGI |
| involved in cellular response to glucocorticoid stimulus |
IMP
IMP: Inferred from mutant phenotype
|
21969592 | MGI |
| involved in cellular response to nutrient levels |
IMP
IMP: Inferred from mutant phenotype
|
21969592 | MGI |
| involved in cognition |
IMP
IMP: Inferred from mutant phenotype
|
21969592 | MGI |
| involved in negative regulation of long-term synaptic potentiation |
IMP
IMP: Inferred from mutant phenotype
|
21969592 | MGI |
| involved in regulation of postsynapse assembly |
IDA
IDA: Inferred from direct assay
|
21969592 | MGI |
| involved in regulation of postsynapse assembly |
IMP
IMP: Inferred from mutant phenotype
|
21969592 | MGI |
| Cellular Component GO Annotation | Evidence | Références | Source |
|---|---|---|---|
| located in actin cytoskeleton |
IDA
IDA: Inferred from direct assay
|
21969592 | MGI |
| is active in glutamatergic synapse |
IDA
IDA: Inferred from direct assay
|
21969592 | MGI |
| is active in glutamatergic synapse |
IMP
IMP: Inferred from mutant phenotype
|
21969592 | MGI |
| located in neuron projection |
IDA
IDA: Inferred from direct assay
|
20298674 | MGI |
| is active in postsynaptic actin cytoskeleton |
IDA
IDA: Inferred from direct assay
|
21969592 | MGI |
| is active in presynaptic actin cytoskeleton |
IDA
IDA: Inferred from direct assay
|
21969592 | MGI |
| located in synapse |
IDA
IDA: Inferred from direct assay
|
21969592 | MGI |
| Protein Preferred Names | Protein Names | |
|---|---|---|
|
actin-associated protein FAM107A |
|