Asxl1 - ASXL transcriptional regulator 1 Gene

Also Known as RGD1561878

Species: Rattus norvegicus

Gene Type: protein coding
Gene ID: 311553

Summary

Predicted to enable peroxisome proliferator activated receptor binding activity; retinoic acid receptor binding activity; and transcription coactivator activity. Involved in negative regulation of lipid storage. Predicted to be located in nucleus. Predicted to be part of PR-DUB complex. Human ortholog(s) of this gene implicated in SM-AHNMD; acute myeloid leukemia; chronic myelomonocytic leukemia; myelodysplastic syndrome; and myelofibrosis. Orthologous to human ASXL1 (ASXL transcriptional regulator 1). [provided by Alliance of Genome Resources, Apr 2022]

Asxl1 Products (12)

mRNA Protein Name
XM_039106659.1 XP_038962587.1 polycomb group protein ASXL1 isoform X1
XM_039106669.1 XP_038962597.1 polycomb group protein ASXL1 isoform X7
XM_039106670.1 XP_038962598.1 polycomb group protein ASXL1 isoform X8
XM_039106660.1 XP_038962588.1 polycomb group protein ASXL1 isoform X2
XM_039106662.1 XP_038962590.1 polycomb group protein ASXL1 isoform X4
XM_039106666.1 XP_038962594.1 polycomb group protein ASXL1 isoform X4
XM_039106665.1 XP_038962593.1 polycomb group protein ASXL1 isoform X4
XM_039106663.1 XP_038962591.1 polycomb group protein ASXL1 isoform X4
XM_039106661.1 XP_038962589.1 polycomb group protein ASXL1 isoform X3
XM_039106664.1 XP_038962592.1 polycomb group protein ASXL1 isoform X4
XM_039106667.1 XP_038962595.1 polycomb group protein ASXL1 isoform X5
XM_039106668.1 XP_038962596.1 polycomb group protein ASXL1 isoform X6

Gene Ontology

  • Biological Process
Biological Process GO Annotation Evidence Références Source
involved in negative regulation of lipid storage IMP
IMP: Inferred from mutant phenotype
24321552 RGD
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

polycomb group protein ASXL1

  • additional sex combs like 1, transcriptional regulator

  • additional sex combs like transcriptional regulator 1

  • putative Polycomb group protein ASXL1

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (4)
Cat. No. Nom du produit
Effect
Pureté
Rare Diseases
HY-W327122 BAP1-IN-1 Inhibitor 99.86% Unkown
HY-RS01114 ASXL1 Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS17970 Asxl1 Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS24441 Asxl1 Rat Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Asxl1 NCBI NCBI:171023