Cers2 - ceramide synthase 2 Gene

Also Known as TRH3; Lass2; 0610013I17Rik

Species: Mus musculus

Gene Type: protein coding
Gene ID: 76893

Summary

Enables sphingosine N-acyltransferase activity. Involved in ceramide biosynthetic process and regulation of lipid metabolic process. Acts upstream of or within sphingolipid biosynthetic process. Predicted to be located in membrane. Predicted to be integral component of membrane. Predicted to be active in endoplasmic reticulum. Is expressed in epidermis stratum basale; epidermis stratum spinosum; limb; liver; and neural tube. Orthologous to human CERS2 (ceramide synthase 2). [provided by Alliance of Genome Resources, Apr 2022]

Cers2 Products (2)

mRNA Protein Name
NM_001320492.1 NP_001307421.1 ceramide synthase 2
NM_029789.2 NP_084065.1 ceramide synthase 2

Gene Ontology

  • Molecular Function
  • Biological Process
Molecular Function GO Annotation Evidence Références Source
enables N-acyltransferase activity IMP
IMP: Inferred from mutant phenotype
19801672 MGI
enables protein binding IPI
IPI: Inferred from physical interaction
26620563 MGI
enables sphingosine N-acyltransferase activity IDA
IDA: Inferred from direct assay
15823095 MGI
Biological Process GO Annotation Evidence Références Source
acts upstream of or within ceramide biosynthetic process IDA
IDA: Inferred from direct assay
15823095 MGI
involved in ceramide biosynthetic process IDA
IDA: Inferred from direct assay
26620563 MGI
involved in ceramide biosynthetic process IMP
IMP: Inferred from mutant phenotype
19801672 MGI
involved in regulation of lipid metabolic process IMP
IMP: Inferred from mutant phenotype
32279995 MGI
acts upstream of or within sphingolipid biosynthetic process IDA
IDA: Inferred from direct assay
15823095 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

ceramide synthase 2

  • LAG1 homolog, ceramide synthase 2

  • LAG1 longevity assurance homolog 2

  • TRAM homolog 3

  • longevity assurance homolog 2

  • sphingosine N-acyltransferase CERS2

  • translocating chain-associating membrane protein homolog 3

  • tumor metastasis-suppressor gene 1 prote

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (6)
Cat. No. Nom du produit
Effect
Pureté
Rare Diseases
HY-133490A ST1074 Inducer 99.41% Unkown
HY-133491 ST1060 Inhibitor / Unkown
HY-183140 DH20931 Activator / Unkown
HY-RS02537 CERS2 Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS22435 Cers2 Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS28958 Cers2 Rat Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Cers2 NCBI NCBI:29956