Chloramultiols A-F, lindenane-type sesquiterpenoid dimers from Chloranthus multistachys

  • J Nat Prod. 2010 May 28;73(5):972-5. doi: 10.1021/np900764n.
Xin-Hui Ran  1 ,  Fei Teng ,  Chang-Xiang Chen ,  Gang Wei ,  Xiao-Jiang Hao ,  Hai-Yang Liu
Affiliations
  • 1. State Key Laboratory of Phytochemistry and Plant Resources in West China, Kunming Institute of Botany, Chinese Academy of Sciences, Kunming 650204, People's Republic of China.
PMID: 20392109 DOI: 10.1021/np900764n
Abstract

Six new highly complex lindenane-type sesquiterpenoid dimers, chloramultiols A-F (1-6), along with six known analogues, were isolated from the whole plant of Chloranthus multistachys. The structures of 1-6 were elucidated on the basis of mass spectrometry (MS) and 1D and 2D NMR spectroscopic analysis. Among them, compounds 1 and 6 contain a unique 18-membered macrocyclic triester ring. All compounds isolated were evaluated for the inhibition of the growth of five tumor cell lines.