2 Results for "

FXR-FGF15 pathway

" in MedChemExpress (MCE) Product Catalog:
Products (2)

2 Results for "FXR-FGF15 pathway" in MCE Product Catalog:

Pueraria Extract
Pueraria Extract
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Cat. No.: HY-N13218
Target:  

Others

Domaines de recherche:  

Cardiovascular Disease

Pueraria Extract is a kudzu extract, and its components include: Isoflavones. Pueraria Extract (ethanol extract) can significantly improve cardiac damage in rats with acute myocardial infarction. Pueraria Extract improves bile acid levels by increasing the expression of CYP7A1 and restoring the diversity of intestinal microbiota. Pueraria Extract can also inhibit the FXR-FGF15 signaling pathway and increase the expression of OST-α to increase bile acid reabsorption and fecal excretion. .
ACT001 hydrochloride
ACT001 hydrochloride
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Cat. No.: HY-128861B
CAS No.: 1403357-80-1
Synonyms: Dimethylaminomicheliolide hydrochloride; DMAMCL hydrochloride
Target:  

Pyroptosis Apoptosis NF-κB Akt NOD-like Receptor (NLR) PPAR FXR

Domaines de recherche:  

Inflammation/Immunology Cancer

ACT001 (Dimethylaminomicheliolide; DMAMCL) hydrochloride is an orally active, blood-brain barrier-permeable anti-inflammatory and anti-tumor agent. ACT001 hydrochloride exerts microglia-mediated neuroanti-inflammatory effects by inhibiting the AKT/NF-κB/NLRP3 axis and suppressing apoptosis (apoptosis). ACT001 hydrochloride inhibits tumor proliferation by upregulating NKTR and inhibiting AKT. ACT001 hydrochloride alleviates metabolic-associated fatty liver disease by regulating gut microbiota and inhibiting ileal FXR. ACT001 hydrochloride inhibits pyroptosis (pyroptosis) and pro-inflammatory cytokine release by activating PPAR-γ and inhibiting NF-κB/NLRP3 .
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