171259-81-7
Chemical Structure
(RS)-AMPA hydrobromide
Synonym(s): (±)-AMPA hydrobromide
- CAS No.: 171259-81-7
- Formula:C7H11BrN2O4
- Molecular Weight:267.08
IUPAC Name: 2-amino-3-(5-methyl-3-oxo-2,3-dihydroisoxazol-4-yl)propanoic acid hydrobromide
InChIKey: KUAHVIUZGLGASU-UHFFFAOYSA-N
SMILES: O=C1C(CC(N)C(O)=O)=C(C)ON1.Br
Biological Activity: (RS)-AMPA hydrobromide ((±)-AMPA hydrobromide) is a glutamate analogue and a potent and selective excitatory neurotransmitter L-glutamic acid agonist. (RS)-AMPA hydrobromide does not interfere with binding sites for kainic acid or NMDA receptors[1][2].
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(RS)-AMPA hydrobromide | 99.50% | (RS)-AMPA hydrobromide ((±)-AMPA hydrobromide) is a glutamate analogue and a potent and selective excitatory neurotransmitter L-glutamic acid agonist. (RS)-AMPA hydrobromide does not interfere with binding sites for kainic acid or NMDA receptors. | ||||||||||||||||||||
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- [1]. Hösli L, et al. Effects of the glutamate analogue AMPA and its interaction with antagonists on cultured rat spinal and brain stem neurones. Neurosci Lett. 1983 Mar 28;36(1):59-62. [Content Brief]
- [2]. Sommer B, et al. Flip and flop: a cell-specific functional switch in glutamate-operated channels of the CNS. Science. 1990 Sep 28;249(4976):1580-5. [Content Brief]
Keywords