586-06-1
586-06-1
Chemical Structure
Metaproterenol
Synonym(s): Orciprenaline
- CAS. Nr.: 586-06-1
- Formula:C11H17NO3
- Molecular Weight:211.26
IUPAC Name: 5-(1-hydroxy-2-(isopropylamino)ethyl)benzene-1,3-diol
InChIKey: LMOINURANNBYCM-UHFFFAOYSA-N
SMILES: OC1=CC(C(O)CNC(C)C)=CC(O)=C1
Biological Activity: Metaproterenol (Orciprenaline) is a direct-acting sympathomimetic and a β2-adrenergic receptor (β2AR) agonist with an IC50 of 68 nM. Metaproterenol also has anti-inflammatory activity[1][2].
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Metaproterenol | Metaproterenol (Orciprenaline) is a direct-acting sympathomimetic and a β2-adrenergic receptor (β2AR) agonist with an IC50 of 68 nM. Metaproterenol also has anti-inflammatory activity. | |||||||||||||||||||||
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References
- [1]. Noh H, et al. Beta 2-adrenergic receptor agonists are novel regulators of macrophage activation in diabetic renal and cardiovascular complications. Kidney Int. 2017 Jul;92(1):101-113. [Content Brief]
- [2]. Ibrahim FA, et al. Highly sensitive spectrofluorimetric method for rapid determination of orciprenaline in biological fluids and pharmaceuticals. Luminescence. 2019 Feb;34(1):77-83. [Content Brief]
Keywords
