859-07-4
859-07-4
Chemical Structure
Cefaloram
- CAS. Nr.: 859-07-4
- Formula:C18H18N2O6S
- Molecular Weight:390.41
InChIKey: GOFCPYKUMJBHBH-RHSMWYFYSA-N
SMILES: OC(C1=C(COC(C)=O)CS[C@@]([C@@H]2NC(CC3=CC=CC=C3)=O)([H])N1C2=O)=O
Biological Activity: Cefaloram is a cephalosporin antibiotic, but it is inactive against clinical cystic fibrosis isolates of Pseudomonas aeruginosa (MIC50 > 128 μg/mL)[1].
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Cefaloram | Cefaloram is a cephalosporin antibiotic, but it is inactive against clinical cystic fibrosis isolates of Pseudomonas aeruginosa (MIC50 > 128 μg/mL). | |||||||||||||||||||||
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References
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[1]. Rineh A, et al. Discovery of Cephalosporin-3'-Diazeniumdiolates That Show Dual Antibacterial and Antibiofilm Effects against Pseudomonas aeruginosa Clinical Cystic Fibrosis Isolates and Efficacy in a Murine Respiratory Infection Model. ACS Infect Dis. 2020 Jun 12;6(6):1460-1479.
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Keywords
