PURA - Pura purine rich element binding protein A Gene

Species: Rattus norvegicus

Gene Type: protein coding
Gene ID: 102557111

Summary

Predicted to enable several functions, including DNA-binding transcription factor activity, RNA polymerase II-specific; nucleic acid binding activity; and transcription regulator inhibitor activity. Predicted to be involved in DNA unwinding involved in DNA replication; dendritic transport of messenger ribonucleoprotein complex; and regulation of transcription, DNA-templated. Predicted to act upstream of or within several processes, including epithelial cell proliferation; lymphocyte proliferation; and negative regulation of transcription, DNA-templated. Located in nucleus. Is active in postsynaptic density. Human ortholog(s) of this gene implicated in autosomal dominant non-syndromic intellectual disability 31. Orthologous to human PURA (purine rich element binding protein A). [provided by Alliance of Genome Resources, Apr 2022]

PURA Products (1)

mRNA Protein Name
NM_001400915.1 NP_001387844.1 transcriptional activator protein Pur-alpha

Gene Ontology

  • Cellular Component
Cellular Component GO Annotation Evidence Verweise Source
is active in postsynaptic density EXP
EXP: Inferred from Experiment
14532281 RGD
is active in postsynaptic density IDA
IDA: Inferred from direct assay
14532281 RGD
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

transcriptional activator protein Pur-alpha

  • WAS/WASL-interacting protein family member 3-like

  • purine-rich single-stranded DNA-binding protein alpha

  • serine/arginine repetitive matrix protein 1-like

  • vegetative cell wall protein gp1-like

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (8)
Art. -Nr. Produktname
Wirkung
Reinheit
Rare Diseases
HY-N10267 Carviolin / Unkown
HY-RS11464 PURA Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-N14807 Neobulgarone A Inhibitor / Unkown
HY-N14808 Neobulgarone B Inhibitor / Unkown
HY-N14809 Neobulgarone C Inhibitor / Unkown
HY-N14810 Neobulgarone D Inhibitor / Unkown
HY-N14812 Neobulgarone E Inhibitor / Unkown
HY-N14814 Neobulgarone F Inhibitor / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens PURA NCBI NCBI:5813