Rab38 - RAB38, member RAS oncogene family Gene

Also Known as Ruby

Species: Rattus norvegicus

Gene Type: protein coding
Gene ID: 252916

Summary

Enables GTP binding activity. Involved in platelet dense granule organization and positive regulation of phosphatidylcholine biosynthetic process. Located in cytosol and vesicle. Colocalizes with Golgi apparatus and endoplasmic reticulum. Used to study Hermansky-Pudlak syndrome; platelet storage pool deficiency; and proteinuria. Orthologous to human RAB38 (RAB38, member Ras oncogene family). [provided by Alliance of Genome Resources, Apr 2022]

Rab38 Products (1)

mRNA Protein Name
NM_145774.3 NP_665717.1 ras-related protein Rab-38

Gene Ontology

  • Molecular Function
  • Biological Process
  • Cellular Component
Molecular Function GO Annotation Evidence Verweise Source
enables GTP binding IDA
IDA: Inferred from direct assay
15843158 RGD
Biological Process GO Annotation Evidence Verweise Source
involved in platelet dense granule organization IMP
IMP: Inferred from mutant phenotype
18983523 RGD
involved in positive regulation of melanin biosynthetic process IMP
IMP: Inferred from mutant phenotype
17043139 RGD
involved in positive regulation of phosphatidylcholine biosynthetic process IDA
IDA: Inferred from direct assay
28438206 RGD
involved in positive regulation of protein localization to cell periphery IMP
IMP: Inferred from mutant phenotype
17043139 RGD
Cellular Component GO Annotation Evidence Verweise Source
located in cell body IDA
IDA: Inferred from direct assay
17043139 RGD
located in melanosome IDA
IDA: Inferred from direct assay
17043139 RGD
located in perinuclear region of cytoplasm IDA
IDA: Inferred from direct assay
17043139 RGD
located in vesicle IDA
IDA: Inferred from direct assay
11337364 RGD
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

ras-related protein Rab-38

  • Rab38, member of RAS oncogene family

  • red eyed dilution

  • ruby or red eyed dilution

  • small GTP binding protein

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (1)
Art. -Nr. Produktname
Wirkung
Reinheit
Rare Diseases
HY-RS11552 RAB38 Human Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Rab38 NCBI NCBI:23682