Myo9b - myosin IXb Gene

Species: Rattus norvegicus

Gene Type: protein coding
Gene ID: 25486

Summary

Enables several functions, including ATP hydrolysis activity; ATP-dependent protein binding activity; and adenyl ribonucleotide binding activity. Involved in Rho protein signal transduction. Located in several cellular components, including actin filament; lamellipodium; and ruffle. Human ortholog(s) of this gene implicated in celiac disease. Orthologous to human MYO9B (Myosin IXB). [provided by Alliance of Genome Resources, Apr 2022]

Myo9b Products (3)

mRNA Protein Name
NM_001271066.2 NP_001257995.1 unconventional myosin-IXb isoform 1
NM_001271067.2 NP_001257996.1 unconventional myosin-IXb isoform 2
NM_012984.4 NP_037116.2 unconventional myosin-IXb isoform 3

Gene Ontology

  • Molecular Function
  • Biological Process
  • Cellular Component
Molecular Function GO Annotation Evidence Verweise Source
enables ADP binding IDA
IDA: Inferred from direct assay
16179355 RGD
enables ADP binding IMP
IMP: Inferred from mutant phenotype
16179355 RGD
enables ATP binding IDA
IDA: Inferred from direct assay
16179355 RGD
enables ATP binding IMP
IMP: Inferred from mutant phenotype
16179355 RGD
enables ATP hydrolysis activity IDA
IDA: Inferred from direct assay
16179355 RGD
enables ATP hydrolysis activity IMP
IMP: Inferred from mutant phenotype
16179355 RGD
enables ATP-dependent protein binding IDA
IDA: Inferred from direct assay
7882973 RGD
enables GTPase activator activity IDA
IDA: Inferred from direct assay
7882973 RGD
enables GTPase activator activity IMP
IMP: Inferred from mutant phenotype
9348541 RGD
enables actin binding IDA
IDA: Inferred from direct assay
7882973 RGD
enables actin filament binding IDA
IDA: Inferred from direct assay
7882973 RGD
enables actin filament binding IMP
IMP: Inferred from mutant phenotype
16179355 RGD
enables microfilament motor activity IDA
IDA: Inferred from direct assay
16179355 RGD
enables microfilament motor activity IMP
IMP: Inferred from mutant phenotype
16179355 RGD
enables protein binding IPI
IPI: Inferred from physical interaction
15644318 RGD
enables zinc ion binding IDA
IDA: Inferred from direct assay
7882973 RGD
Biological Process GO Annotation Evidence Verweise Source
involved in Rho protein signal transduction IDA
IDA: Inferred from direct assay
7882973 RGD
Cellular Component GO Annotation Evidence Verweise Source
located in actin filament IDA
IDA: Inferred from direct assay
9348541 RGD
located in lamellipodium IDA
IDA: Inferred from direct assay
9348541 RGD
located in perinuclear region of cytoplasm IDA
IDA: Inferred from direct assay
9348541 RGD
located in ruffle IDA
IDA: Inferred from direct assay
9348541 RGD
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

unconventional myosin-IXb

  • Unconventional myosin from rat 3

  • myr 5

  • unconventional myosin-9b

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (3)
Art. -Nr. Produktname
Wirkung
Reinheit
Rare Diseases
HY-RS08953 MYO9B Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS22665 Myo9b Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS29179 Myo9b Rat Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Myo9b NCBI NCBI:4650