Slitrk1 - SLIT and NTRK-like family, member 1 Gene

Species: Rattus norvegicus

Gene Type: protein coding
Gene ID: 306147

Summary

Involved in regulation of synapse organization. Is active in GABA-ergic synapse and glutamatergic synapse. Is integral component of postsynaptic density membrane. Human ortholog(s) of this gene implicated in Gilles de la Tourette syndrome and trichotillomania. Orthologous to human SLITRK1 (SLIT and NTRK like family member 1). [provided by Alliance of Genome Resources, Apr 2022]

Slitrk1 Products (1)

mRNA Protein Name
NM_001107283.1 NP_001100753.1 SLIT and NTRK-like protein 1 precursor

Gene Ontology

  • Biological Process
  • Cellular Component
Biological Process GO Annotation Evidence Verweise Source
involved in regulation of synapse organization IDA
IDA: Inferred from direct assay
27273464 RGD
involved in regulation of synapse organization IMP
IMP: Inferred from mutant phenotype
27273464 RGD
Cellular Component GO Annotation Evidence Verweise Source
is active in GABA-ergic synapse IDA
IDA: Inferred from direct assay
27273464 RGD
is active in GABA-ergic synapse IMP
IMP: Inferred from mutant phenotype
27273464 RGD
is active in glutamatergic synapse IDA
IDA: Inferred from direct assay
27273464 RGD
is active in glutamatergic synapse IMP
IMP: Inferred from mutant phenotype
27273464 RGD
is active in postsynaptic density membrane IDA
IDA: Inferred from direct assay
23345436 RGD
is active in postsynaptic membrane IDA
IDA: Inferred from direct assay
29983322 RGD
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

SLIT and NTRK-like protein 1

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (3)
Art. -Nr. Produktname
Wirkung
Reinheit
Rare Diseases
HY-RS13373 SLITRK1 Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS20219 Slitrk1 Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS26726 Slitrk1 Rat Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Slitrk1 NCBI NCBI:114798