EHMT1 - euchromatic histone lysine methyltransferase 1 Gene

Species: Rattus norvegicus

Gene Type: protein coding
Gene ID: 362078

About EHMT1

Primary_assembly 3: 7,580,683-7,729,007 reverse strand.mRatBN7.2:CM026976.1

This gene has 5 transcripts (splice variants), 314 orthologues, 23 paralogues and is associated with 16 phenotypes. Biased expression in Thymus (RPKM 14.5), Adrenal (RPKM 113.7) and 9 other tissues.

Summary

Predicted to enable several functions, including C2H2 zinc finger domain binding activity; histone-lysine N-methyltransferase activity; and p53 binding activity. Involved in response to fungicide. Predicted to be located in nuclear body. Human ortholog(s) of this gene implicated in Kleefstra syndrome and Kleefstra syndrome 1. Orthologous to human EHMT1 (euchromatic histone lysine methyltransferase 1). [provided by Alliance of Genome Resources, Apr 2022]

EHMT1 Products (1)

mRNA Protein Name
NM_001108572.1 NP_001102042.1 histone-lysine N-methyltransferase EHMT1

Gene Ontology

  • Biological Process
Biological Process GO Annotation Evidence Verweise Source
involved in response to fungicide IEP
IEP: Inferred from expression pattern
22496781 RGD
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern

EHMT1 Protein Structure

EHMT_ZBD

EHMT_ZBD: cd20905 (527 - 657)

Ank_2

Ank_2: pfam12796 (753 - 847)

ANK

ANK: sd00045 (785 - 814)

ANK

ANK: sd00045 (816 - 847)

Ank_2

Ank_2: pfam12796 (821 - 914)

ANK

ANK: sd00045 (849 - 881)

ANK

ANK: sd00045 (883 - 914)

Ank_2

Ank_2: pfam12796 (888 - 980)

ANK

ANK: sd00045 (916 - 947)

ANK

ANK: sd00045 (949 - 980)

SET_EHMT1

SET_EHMT1: cd10535 (1047 - 1277)

  • 0
  • 300
  • 600
  • 900
  • 1200
  • 1310 a.a.
Protein Preferred Names Protein Names

histone-lysine N-methyltransferase EHMT1

  • euchromatic histone methyltransferase 1

  • euchromatic histone-lysine N-methyltransferase 1

  • histone-lysine N-methyltransferase EHMT1-like

  • histone-lysine N-methyltransferase, H3 lysine-9 specific 5

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (12)
Art. -Nr. Produktname
Wirkung
Reinheit
Rare Diseases
HY-15273 UNC0638 99.84% Unkown
HY-12583 A-366 Inhibitor 98.13% Unkown
HY-13808 UNC 0631 Inhibitor 99.27% Unkown
HY-111778 EHMT2-IN-1 Inhibitor 99.85% Unkown
HY-13807 UNC0646 Inhibitor 99.38% Unkown
HY-161759 MS152 Inhibitor 99.36% Unkown
HY-111904 EHMT2-IN-2 Inhibitor 99.0% Unkown
HY-13808R UNC 0631 (Standard) Inhibitor 99.54% Unkown
HY-RS04227 EHMT1 Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS04228 Ehmt1 Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS04229 EHMT1 Rat Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-110093 UNC0638 hydrate Inhibitor / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens EHMT1 NCBI NCBI:79813