1. Epigenetics
  2. Histone Methyltransferase

A-366 

Cat. No.: HY-12583 Purity: 98.47%
Handling Instructions

A-366 is a potent histone methyltransferase G9a inhibitor with an IC50 of 3.3 nM.

For research use only. We do not sell to patients.

A-366 Chemical Structure

A-366 Chemical Structure

CAS No. : 1527503-11-2

Size Price Stock Quantity
Free Sample (0.5-1 mg)   Apply now  
10 mM * 1 mL in DMSO USD 86 In-stock
Estimated Time of Arrival: December 31
5 mg USD 78 In-stock
Estimated Time of Arrival: December 31
10 mg USD 132 In-stock
Estimated Time of Arrival: December 31
50 mg USD 528 In-stock
Estimated Time of Arrival: December 31
100 mg   Get quote  
200 mg   Get quote  

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    A-366 purchased from MCE. Usage Cited in: Theranostics. 2018 Apr 15;8(10):2884-2895.

    Plk1 levels are decreased companied with p53K373me2 decline in HCT116 cells treated with BRD9539.
    • Biological Activity

    • Technical Information

    • Purity & Documentation

    • References

    Description

    A-366 is a potent histone methyltransferase G9a inhibitor with an IC50 of 3.3 nM.

    Solvent & Solubility
    In Vitro: 

    10 mM in DMSO

    Preparing
    Stock Solutions
    Concentration Solvent Mass 1 mg 5 mg 10 mg
    1 mM 3.0355 mL 15.1773 mL 30.3545 mL
    5 mM 0.6071 mL 3.0355 mL 6.0709 mL
    10 mM 0.3035 mL 1.5177 mL 3.0355 mL
    *Please refer to the solubility information to select the appropriate solvent.
    References
    Molecular Weight

    329.44

    Formula

    C₁₉H₂₇N₃O₂

    CAS No.

    1527503-11-2

    SMILES

    COC1=CC2=C(N=C(N)C23CCC3)C=C1OCCCN4CCCC4

    Storage
    Powder -20°C 3 years
      4°C 2 years
    In solvent -80°C 6 months
      -20°C 1 month
    Shipping

    Room temperature in continental US; may vary elsewhere

    • Molarity Calculator

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    This equation is commonly abbreviated as: C1V1 = C2V2

    Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
    × = ×
    C1   V1   C2   V2

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    Inquiry Information

    Product Name:
    A-366
    Cat. No.:
    HY-12583
    Quantity:

    A-366

    Cat. No.: HY-12583