936107-90-3
Chemical Structure
Fluorescein-12-dGTP
- CAS No.: 936107-90-3
- Formula:C41H41N6O20P3
- Molecular Weight:1030.71
InChIKey: KQANGBZEKUNZBQ-ABAVYFCKSA-N
SMILES: O[C@H]1C[C@H](N(C2=C3C(NC(N)=N2)=O)C=C3C#CCNC(CCCCCNC(C4=CC=C(C(C5=C(C(OC6=C5C=CC(O)=C6)=C7)C=CC7=O)=C4)C(O)=O)=O)=O)O[C@@H]1COP(OP(OP(O)(O)=O)(O)=O)(O)=O
Biological Activity: Fluorescein-12-dGTP is a fluorescein-labeled deoxyguanosine triphosphate. Fluorescein-12-dGTP incorporates into complementary allele-specific primers at SNP sites, enabling FRET with cationic conjugated polymer PFP via DNA-PFP electrostatic interactions. Fluorescein-12-dGTP incorporates into G-allele-specific primers for homozygous G/G SNP genotypes to enable genotype discrimination. Fluorescein-12-dGTP serves as a fluorescently labeled nucleotide for homogeneous solution-based SNP and FRET genotyping assays (Ex/Em = 498/517 nm)[1].
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Fluorescein-12-dGTP | Fluorescein-12-dGTP is a fluorescein-labeled deoxyguanosine triphosphate. Fluorescein-12-dGTP incorporates into complementary allele-specific primers at SNP sites, enabling FRET with cationic conjugated polymer PFP via DNA-PFP electrostatic interactions. Fluorescein-12-dGTP incorporates into G-allele-specific primers for homozygous G/G SNP genotypes to enable genotype discrimination. Fluorescein-12-dGTP serves as a fluorescently labeled nucleotide for homogeneous solution-based SNP and FRET genotyping assays (Ex/Em = 498/517 nm). | |||||||||||||||||||||
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Keywords
