IPCEF1 - interaction protein for cytohesin exchange factors 1 Gene

Also Known as PIP3E; PIP3-E

Species: Homo sapiens

Gene Type: protein coding
Gene ID: 26034

About IPCEF1

Cytogenetic location: 6q25.2 Genomic coordinates (GRCh38): 6:154,154,496-154,356,803 (from NCBI)

This gene has 13 transcripts (splice variants), 97 orthologues and 4 paralogues. Biased expression in thyroid (RPKM 13.5), brain (RPKM 6.8) and 9 other tissues.

Summary

Predicted to enable peroxidase activity. Predicted to be involved in response to oxidative stress. Predicted to be located in cytosol and plasma membrane. [provided by Alliance of Genome Resources, Apr 2022]

IPCEF1 Products (7)

mRNA Protein Name
NM_001130699.2 NP_001124171.1 interactor protein for cytohesin exchange factors 1 isoform 1
NM_001130700.2 NP_001124172.1 interactor protein for cytohesin exchange factors 1 isoform 1
NM_001394799.1 NP_001381728.1 interactor protein for cytohesin exchange factors 1 isoform 1
NM_001394800.1 NP_001381729.1 interactor protein for cytohesin exchange factors 1 isoform 1
NM_001394801.1 NP_001381730.1 interactor protein for cytohesin exchange factors 1 isoform 1
NM_001394802.1 NP_001381731.1 interactor protein for cytohesin exchange factors 1 isoform 2
NM_015553.3 NP_056368.1 interactor protein for cytohesin exchange factors 1 isoform 2

Gene Ontology

  • Molecular Function
Molecular Function GO Annotation Evidence References Source
enables protein binding IPI
IPI: Inferred from physical interaction
22085542 GOA
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern

IPCEF1 Protein Structure

PH

PH: PH domain (44 - 137)

  • 0
  • 100
  • 200
  • 300
  • 400
  • 437 a.a.
Protein Preferred Names Protein Names

interactor protein for cytohesin exchange factors 1

  • interaction protein for cytohesin exchange factors 1 Interaction protein for cytohesin exchange factors 1

IPCEF1 Protein-protein interaction Information

Type
Protein Name Protein ID Interactor Interactor Species Interactor ID Detection Method References
Intra
IPCEF1 Q8WWN9 CYTH4 Homo sapiens Q9UIA0
Y2H Prey Pooling
32296183
Intra
IPCEF1 Q8WWN9 CYTH4 Homo sapiens Q9UIA0
Validated Y2H
32296183
Intra
IPCEF1 Q8WWN9 CYTH4 Homo sapiens Q9UIA0
Anti Tag CoIP
33961781
Intra
IPCEF1 Q8WWN9 CYTH4 Homo sapiens Q9UIA0
Y2H Array
32296183
Intra
IPCEF1 Q8WWN9 CYTH2 Homo sapiens Q99418
Y2H Array
32296183
Intra
IPCEF1 Q8WWN9 CYTH2 Homo sapiens Q99418
Anti Tag CoIP
33961781
Intra
IPCEF1 Q8WWN9 CYTH2 Homo sapiens Q99418
Y2H Prey Pooling
32296183
Intra
IPCEF1 Q8WWN9 CYTH2 Homo sapiens Q99418
Validated Y2H
32296183
Intra
IPCEF1 Q8WWN9 CEP70 Homo sapiens Q8NHQ1
Y2H Prey Pooling
32296183
Intra
IPCEF1 Q8WWN9 CEP70 Homo sapiens Q8NHQ1
Y2H Array
32296183
Intra
IPCEF1 Q8WWN9 CYTH1 Homo sapiens Q15438
Y2H Prey Pooling
32296183
Intra
IPCEF1 Q8WWN9 CYTH1 Homo sapiens Q15438
Anti Tag CoIP
33961781
Intra
IPCEF1 Q8WWN9 CYTH1 Homo sapiens Q15438
Y2H Array
32296183
Cross: Cross-species interaction Intra: Intraspecies interaction

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (1)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-RS06864 IPCEF1 Human Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Bos taurus IPCEF1 VGNC VGNC:30239
Mus musculus IPCEF1 MGD MGI:2444159
Macaca mulatta IPCEF1 VGNC VGNC:83429
Rattus norvegicus IPCEF1 RGD RGD:735159
Others IPCEF1 NCBI