265652-71-9
Chemical Structure
Xanthoangelol F
- CAS No.: 265652-71-9
- Formula:C26H30O4
- Molecular Weight:406.52
IUPAC Name: (E)-1-(3-((E)-3,7-dimethylocta-2,6-dien-1-yl)-2-hydroxy-4-methoxyphenyl)-3-(4-hydroxyphenyl)prop-2-en-1-one
InChIKey: XBFSDEKOTLYPJU-SXZUIPJJSA-N
SMILES: C(/C=C(/CCC=C(C)C)\C)C1=C(OC)C=CC(C(/C=C/C2=CC=C(O)C=C2)=O)=C1O
Biological Activity: Xanthoangelol F is a prenylated (geranylated) chalcone and Antibacterial agent. Xanthoangelol F can be isolated from Angelica keiskei. Xanthoangelol F inhibits the growth of Gram-positive bacteria Bacillus subtilis, Staphylococcus epidermidis, and Micrococcus luteus, with an MIC of 64 μg/mL[1][2].
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Xanthoangelol F | Xanthoangelol F is a prenylated (geranylated) chalcone and Antibacterial agent. Xanthoangelol F can be isolated from Angelica keiskei. Xanthoangelol F inhibits the growth of Gram-positive bacteria Bacillus subtilis, Staphylococcus epidermidis, and Micrococcus luteus, with an MIC of 64 μg/mL. | |||||||||||||||||||||
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- [1]. Mizar P, et al. Total Synthesis of Xanthoangelol B and Its Various Fragments: Toward Inhibition of Virulence Factor Production of Staphylococcus aureus. J Med Chem. 2018;61(23):10473-10487. [Content Brief]
- [2]. Sugamoto K, et al. Synthesis and antibacterial activity of chalcones bearing prenyl or geranyl groups from Angelica keiskei[J]. Tetrahedron, 2011, 67(29): 5346-5359.
Keywords
