3680-69-1
![4-Chloro-7H-pyrrolo[2,3-d]pyrimidine Chemical Structure](http://file.medchemexpress.cn/product_pic/hy-40351.gif "4-Chloro-7H-pyrrolo[2,3-d]pyrimidine Chemical Structure")
3680-69-1
Chemical Structure
4-Chloro-7H-pyrrolo[2,3-d]pyrimidine
- CAS No.: 3680-69-1
- Formula:C6H4ClN3
- Molecular Weight:153.57
IUPAC Name: 4-chloro-7H-pyrrolo[2,3-d]pyrimidine
InChIKey: BPTCCCTWWAUJRK-UHFFFAOYSA-N
SMILES: ClC1=C2C(NC=C2)=NC=N1
Biological Activity: 4-Chloro-7H-pyrrolo[2,3-d]pyrimidine is a nitrogen-containing heterocyclic organic synthesis intermediate that can be used for the synthesis of JAK and PKB/Akt inhibitors[1][2].
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4-Chloro-7H-pyrrolo[2,3-d]pyrimidine | 99.82% | 4-Chloro-7H-pyrrolo[2,3-d]pyrimidine is a nitrogen-containing heterocyclic organic synthesis intermediate that can be used for the synthesis of JAK and PKB/Akt inhibitors. | ||||||||||||||||||||
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References
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[1]. Liu Y, et al. Discovery of 4-(Piperazin-1-yl)-7H-pyrrolo[2,3-d]pyrimidine Derivatives as Akt Inhibitors. Arch Pharm (Weinheim). 2016 May;349(5):356-62.
[Content Brief] -
[2]. Caldwell JJ, et al. Identification of 4-(4-aminopiperidin-1-yl)-7 H-pyrrolo [2, 3-d] pyrimidines as selective inhibitors of protein kinase B through fragment elaboration. Journal of medicinal chemistry. 2008 Apr 10;51(7):2147-57.
Keywords
