Mtbp - Mdm2, transformed 3T3 cell double minute p53 binding protein Gene

Also Known as MDM2BP

Species: Mus musculus

Gene Type: protein coding
Gene ID: 105837

Summary

Acts upstream of or within negative regulation of cell population proliferation; negative regulation of mitotic nuclear division; and traversing start control point of mitotic cell cycle. Located in kinetochore. Is expressed in cerebellum; midbrain ventricular layer; olfactory cortex ventricular layer; and telencephalon ventricular layer. Orthologous to human MTBP (MDM2 binding protein). [provided by Alliance of Genome Resources, Apr 2022]

Mtbp Products (2)

mRNA Protein Name
NM_001168250.1 NP_001161722.1 mdm2-binding protein isoform 2
NM_134092.3 NP_598853.3 mdm2-binding protein isoform 1

Gene Ontology

  • Molecular Function
  • Biological Process
  • Cellular Component
Molecular Function GO Annotation Evidence Références Source
enables protein binding IPI
IPI: Inferred from physical interaction
10906133 MGI
Biological Process GO Annotation Evidence Références Source
acts upstream of or within negative regulation of cell population proliferation IDA
IDA: Inferred from direct assay
10906133 MGI
acts upstream of or within negative regulation of mitotic nuclear division IDA
IDA: Inferred from direct assay
21274008 MGI
acts upstream of or within traversing start control point of mitotic cell cycle IDA
IDA: Inferred from direct assay
10906133 MGI
Cellular Component GO Annotation Evidence Références Source
located in kinetochore IDA
IDA: Inferred from direct assay
21274008 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

mdm2-binding protein

  • mMTBP

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (1)
Cat. No. Nom du produit
Effect
Pureté
Rare Diseases
HY-RS08753 MTBP Human Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Mtbp NCBI NCBI:27085