MTBP - MDM2 binding protein Gene

Homo sapiens

Also known as MDM2BP

Gene ID: 27085 | Gene type: protein coding

About MTBP

Cytogenetic location: 8q24.12 Genomic coordinates (GRCh38): 8:120,445,419-120,523,636 (from NCBI)

This gene has 8 transcripts (splice variants) and 198 orthologues. Broad expression in testis (RPKM 2.1), lymph node (RPKM 1.4) and 24 other tissues.

Summary

This gene encodes a protein that interacts with the oncoprotein mouse double minute 2. The encoded protein regulates progression through the cell cycle and may be involved in tumor formation. [provided by RefSeq, Aug 2012]

MTBP Products(1)

mRNA	Protein	Name
NM_022045.5	NP_071328.2	mdm2-binding protein

MTBP Protein Structure

MTBP_N

MTBP_mid

MTBP_C

0
200
400
600
800
904 a.a.

Protein Preferred Names

Protein Names

mdm2-binding protein

MDM2 (mouse double minute 2)-binding protein, 104kD

Related Diseases

Diseases

Alias

Van Esch-O'Driscoll Syndrome

X-Linked Intellectual Disability, Van Esch Type	VEODS
Mrxsveod	Mental Retardation, X-Linked, Syndromic, Van Esch-O'Driscoll Type
X-Linked Syndromic Mental Retardation Van Esch-O'Driscoll Type

Diseases	Alias
Waldenstroem'S Macroglobulinemia	Waldenstroem'S Macroglobulinemia Waldenstroem'S Macroglobulinemia Macroglobulinemia Of Waldenstrom Lymphoplasmacytic Lymphoma With Igm Gammopathy Lymphoplasmacytic Lymphoma Waldenstroem'S Macroglobulinemia Waldenstroem'S Macroglobulinemia Macroglobulinemia Of Waldenstrom Lymphoplasmacytic Lymphoma With Igm Gammopathy Lymphoplasmacytic Lymphoma

Cat. No.	Product Name	Effect	Purity	Rare Diseases
HY-RS08753	MTBP Human Pre-designed siRNA Set A		/	Unkown

Orthologs Information

Species	Symbol	Source	ID
Rattus norvegicus	MTBP	RGD	RGD:1565672
Felis catus	MTBP	VGNC	VGNC:68336
Bos taurus	MTBP	VGNC	VGNC:31716
Canis familiaris	MTBP	VGNC	VGNC:43458
Macaca mulatta	MTBP	VGNC	VGNC:74944
Mus musculus	MTBP	MGD	MGI:2146005