A selective fluoroionophore based on BODIPY-functionalized magnetic silica nanoparticles: removal of Pb2+ from human blood

  • Angew Chem Int Ed Engl. 2009;48(7):1239-43. doi: 10.1002/anie.200804714.
Hye Young Lee  1 ,  Doo Ri Bae ,  Ji Chan Park ,  Hyunjoon Song ,  Won Seok Han ,  Jong Hwa Jung
Affiliations
  • 1. Department of Chemistry and Research Institute of Natural Sciences and Environmental Biotechnology National Core Research Center, Gyeongsang National University, Jinju 660-701, Korea.
PMID: 19130522 DOI: 10.1002/anie.200804714
Abstract

Get the lead out: The title fluorescence receptor exhibits a high affinity and selectivity for Pb(2+) over competing metal ions in water (see picture) with an overall emission change of approximately 8-fold at the emission maximum for Pb(2+). The fluorescence receptor can remove 96 % of 100 ppb Pb(2+) from human blood, and can be useful and effective for the selective and rapid removal of Pb(2+) in vivo.

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