511-12-6
Chemical Structure
Dihydroergotamine
Synonym(s): DFN-19
- CAS No.: 511-12-6
- Formula:C33H37N5O5
- Molecular Weight:583.68
IUPAC Name: (6aR,9R,10aR)-N-((2R,5S,10aS,10bS)-5-benzyl-10b-hydroxy-2-methyl-3,6-dioxooctahydro-8H-oxazolo[3,2-a]pyrrolo[2,1-c]pyrazin-2-yl)-7-methyl-4,6,6a,7,8,9,10,10a-octahydroindolo[4,3-fg]quinoline-9-carboxamide
InChIKey: LUZRJRNZXALNLM-JGRZULCMSA-N
SMILES: O[C@@]([C@@](CCC1)([H])N1C2=O)(O[C@](NC([C@@H](CN(C)[C@]3([H])C4)C[C@]3([H])C5=C6C4=CNC6=CC=C5)=O)(C)C7=O)N7[C@H]2CC8=CC=CC=C8
Biological Activity: Dihydroergotamine (DFN-19) is a BBB-permeable and semisynthetic, hydrogenated ergot alkaloid. Dihydroergotamine can cause vasoconstriction by stimulating alpha-adrenergic and 5-HT2A receptors. Dihydroergotamine can be used in the research of migraine[1].
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Dihydroergotamine | Dihydroergotamine (DFN-19) is a BBB-permeable and semisynthetic, hydrogenated ergot alkaloid. Dihydroergotamine can cause vasoconstriction by stimulating alpha-adrenergic and 5-HT2A receptors. Dihydroergotamine can be used in the research of migraine. | |||||||||||||||||||||
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Dihydroergotamine-d3 | Dihydroergotamine-d3 is deuterium labeled Dihydroergotamine (hydrochloride). | |||||||||||||||||||||
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