Zic5 - zinc finger protein of the cerebellum 5 Gene

Also Known as Opr; 1700049L20Rik

Species: Mus musculus

Gene Type: protein coding
Gene ID: 65100

Summary

Enables DNA-binding transcription factor activity and RNA polymerase II transcription regulatory region sequence-specific DNA binding activity. Acts upstream of or within cell differentiation; forebrain development; and neural tube closure. Located in nucleus. Is expressed in several structures, including central nervous system; early conceptus; limb mesenchyme; sensory organ; and trunk paraxial mesenchyme. Orthologous to human ZIC5 (Zic family member 5). [provided by Alliance of Genome Resources, Apr 2022]

Zic5 Products (1)

mRNA Protein Name
NM_022987.3 NP_075363.1 zinc finger protein ZIC 5

Gene Ontology

  • Molecular Function
  • Biological Process
  • Cellular Component
Molecular Function GO Annotation Evidence References Source
enables DNA binding IDA
IDA: Inferred from direct assay
15465018 MGI
enables DNA-binding transcription factor activity IDA
IDA: Inferred from direct assay
15465018 MGI
enables RNA polymerase II transcription regulatory region sequence-specific DNA binding IDA
IDA: Inferred from direct assay
18298960 MGI
Biological Process GO Annotation Evidence References Source
acts upstream of or within forebrain development IMP
IMP: Inferred from mutant phenotype
15736266 MGI
acts upstream of or within neural crest cell differentiation IMP
IMP: Inferred from mutant phenotype
15136147 MGI
acts upstream of or within neural tube closure IMP
IMP: Inferred from mutant phenotype
15136147 MGI
NOT involved in positive regulation of DNA-templated transcription IDA
IDA: Inferred from direct assay
15465018 MGI
Cellular Component GO Annotation Evidence References Source
located in nucleus IDA
IDA: Inferred from direct assay
15465018 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

zinc finger protein ZIC 5

  • Zic family member 5 (odd-paired homolog, Drosophila)

  • odd paired-related protein

  • odd-paired related

  • opa-related protein

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (3)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-RS16077 ZIC5 Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS21463 Zic5 Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS27981 Zic5 Rat Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Zic5 NCBI NCBI:85416