Cyp2c11 - cytochrome P450, subfamily 2, polypeptide 11 Gene

Also Known as Cyp2c; CYP2CII; Cyp2c11l

Species: Rattus norvegicus

Gene Type: protein coding
Gene ID: 29277

Summary

Enables arachidonic acid 11,12-epoxygenase activity; arachidonic acid 14,15-epoxygenase activity; and testosterone 16-alpha-hydroxylase activity. Involved in epoxygenase P450 pathway and icosanoid biosynthetic process. Located in endoplasmic reticulum membrane. Biomarker of end stage renal disease; hypertension; and mental depression. Orthologous to human CYP2C18 (Cytochrome P450 family 2 subfamily C member 18). [provided by Alliance of Genome Resources, Apr 2022]

Cyp2c11 Products (2)

mRNA Protein Name
NM_019184.2 NP_062057.2 cytochrome P450 2C11 precursor
NM_019184.2 NP_062057.2 cytochrome P450 2C11 precursor

Gene Ontology

  • Molecular Function
  • Biological Process
  • Cellular Component
Molecular Function GO Annotation Evidence References Source
enables arachidonate 11,12-epoxygenase activity IDA
IDA: Inferred from direct assay
10491410 RGD
enables arachidonate 14,15-epoxygenase activity IDA
IDA: Inferred from direct assay
10491410 RGD
enables monooxygenase activity IDA
IDA: Inferred from direct assay
15766564 RGD
enables testosterone 16-alpha-hydroxylase activity IDA
IDA: Inferred from direct assay
2434473 RGD
enables testosterone 16-alpha-hydroxylase activity IMP
IMP: Inferred from mutant phenotype
8611037 RGD
Biological Process GO Annotation Evidence References Source
involved in epoxygenase P450 pathway IDA
IDA: Inferred from direct assay
10491410 RGD
involved in icosanoid biosynthetic process IDA
IDA: Inferred from direct assay
15766564 RGD
Cellular Component GO Annotation Evidence References Source
located in endoplasmic reticulum membrane IDA
IDA: Inferred from direct assay
2434473 RGD
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

cytochrome P450 2C11

  • CYPIIC11

  • P-450(M-1)

  • P450-UT-A

  • P450H

  • UT-2

  • cytochrome P-450(M-1)

  • cytochrome P450 2C11-like

  • cytochrome P450, 2c29

  • cytochrome P450, subfamily IIC (mephenytoin 4-hydroxylase), polypeptide 11

  • cytochrome P450-UT-2

  • cytochrome P450-UT-A

  • cytochrome P450H

Related Agents

  • Approval
  • Pre-clinical Phase

Approval

Bioactive Molecules (1)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-N0482 Phillyrin 98.82% Unkown

Pre-clinical Phase

Bioactive Molecules (1)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-B1351 Bilberry Extract / Unkown