Palb2 - partner and localizer of BRCA2 Gene

Predicted to enable DNA binding activity. Predicted to be involved in double-strand break repair via homologous recombination. Predicted to act upstream of or within several processes, including animal organ development; chordate embryonic development; and post-anal tail morphogenesis. Predicted to be part of protein-containing complex. Predicted to be active in nucleoplasm. Human ortholog(s) of this gene implicated in Fanconi anemia complementation group N; breast cancer; and pancreatic Cancer. Orthologous to human PALB2 (partner and localizer of BRCA2). [provided by Alliance of Genome Resources, Apr 2022]