Nelfe - negative elongation factor complex member E Gene

Also Known as Rd; Rdbp

Species: Rattus norvegicus

Gene Type: protein coding
Gene ID: 294258

Summary

Enables chromatin binding activity. Involved in positive regulation of ERK1 and ERK2 cascade; positive regulation of histone H3-K4 methylation; and regulation of transcription by RNA polymerase II. Located in nucleus. Orthologous to human NELFE (negative elongation factor complex member E). [provided by Alliance of Genome Resources, Apr 2022]

Nelfe Products (2)

mRNA Protein Name
NM_001165901.1 NP_001159373.1 negative elongation factor E
NM_212548.2 NP_997713.1 negative elongation factor E

Gene Ontology

  • Molecular Function
  • Biological Process
Molecular Function GO Annotation Evidence References Source
enables chromatin binding IDA
IDA: Inferred from direct assay
20097260 RGD
enables chromatin binding IMP
IMP: Inferred from mutant phenotype
21623364 RGD
Biological Process GO Annotation Evidence References Source
involved in negative regulation of transcription by RNA polymerase II IMP
IMP: Inferred from mutant phenotype
20097260 RGD
involved in positive regulation of ERK1 and ERK2 cascade IMP
IMP: Inferred from mutant phenotype
19014935 RGD
involved in positive regulation of protein modification process IMP
IMP: Inferred from mutant phenotype
21623364 RGD
involved in positive regulation of transcription by RNA polymerase II IMP
IMP: Inferred from mutant phenotype
21623364 RGD
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

negative elongation factor E

  • RD RNA-binding protein

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (1)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-RS09203 NELFE Human Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Nelfe NCBI NCBI:7936