Slc25a1 - solute carrier family 25 member 1 Gene

Also Known as Cic; Ctp; Slc20a3

Species: Rattus norvegicus

Gene Type: protein coding
Gene ID: 29743

Summary

This gene encodes a member of the mitochondrial carrier family. The encoded protein is responsible for the movement of tricarboxylates, such as citrate, across the inner mitochondrial membrane. It is essential to the bioenergetics of hepatic cells, supplying the cytoplasm with a carbon source for fatty acid and sterol biosynthesis, and NAD+ for the glycolytic pathway. [provided by RefSeq, Jul 2008]

Slc25a1 Products (1)

mRNA Protein Name
NM_017307.3 NP_059003.1 tricarboxylate transport protein, mitochondrial precursor
Molecular Function GO Annotation Evidence References Source
enables citrate secondary active transmembrane transporter activity IDA
IDA: Inferred from direct assay
2804096 RGD
Biological Process GO Annotation Evidence References Source
involved in mitochondrial citrate transmembrane transport IDA
IDA: Inferred from direct assay
2804096 RGD
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

tricarboxylate transport protein, mitochondrial

  • citrate carrier

  • citrate transport protein

  • citrate transporter) member 1

  • mitochondrial tricarboxylate carrier

  • solute carrier family 25 (mitochondrial carrier, citrate transporter), member 1

Orthologs Information

Species Symbol Source ID
Homo sapiens Slc25a1 NCBI NCBI:6576