Sema5a - semaphorin 5A Gene

Species: Rattus norvegicus

Gene Type: protein coding
Gene ID: 310207

Summary

Enables chondroitin sulfate proteoglycan binding activity; heparan sulfate proteoglycan binding activity; and syndecan binding activity. Involved in nervous system development and signal clustering. Located in membrane. Orthologous to human SEMA5A (semaphorin 5A). [provided by Alliance of Genome Resources, Apr 2022]

Sema5a Products (1)

mRNA Protein Name
NM_001107659.2 NP_001101129.1 semaphorin-5A precursor

Gene Ontology

  • Molecular Function
  • Biological Process
  • Cellular Component
Molecular Function GO Annotation Evidence References Source
enables chondroitin sulfate proteoglycan binding IMP
IMP: Inferred from mutant phenotype
15603739 RGD
enables heparan sulfate proteoglycan binding IMP
IMP: Inferred from mutant phenotype
15603739 RGD
enables syndecan binding IPI
IPI: Inferred from physical interaction
15603739 RGD
Biological Process GO Annotation Evidence References Source
involved in axonal fasciculation IDA
IDA: Inferred from direct assay
15603739 RGD
involved in diencephalon development IMP
IMP: Inferred from mutant phenotype
15603739 RGD
involved in negative regulation of axon extension involved in axon guidance IMP
IMP: Inferred from mutant phenotype
15603739 RGD
involved in positive regulation of axon extension involved in axon guidance IMP
IMP: Inferred from mutant phenotype
15603739 RGD
involved in signal clustering IMP
IMP: Inferred from mutant phenotype
15603739 RGD
Cellular Component GO Annotation Evidence References Source
located in membrane IDA
IDA: Inferred from direct assay
15603739 RGD
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

semaphorin-5A

  • sema F

  • sema domain, seven thrombospondin repeats (type 1 and type 1-like), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 5A

  • semaphorin-F

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (3)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-RS12663 SEMA5A Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS19268 Sema5a Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS25757 Sema5a Rat Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Sema5a NCBI NCBI:9037