Sh3glb2 - SH3 domain-containing GRB2-like endophilin B2 Gene

Species: Rattus norvegicus

Gene Type: protein coding
Gene ID: 311848

Summary

Predicted to enable identical protein binding activity. Predicted to be involved in membrane organization. Predicted to be located in cytosol and nucleoplasm. Predicted to be active in membrane. Orthologous to human SH3GLB2 (SH3 domain containing GRB2 like, endophilin B2). [provided by Alliance of Genome Resources, Apr 2022]

Sh3glb2 Products (2)

mRNA Protein Name
NM_001393780.1 NP_001380709.1 endophilin-B2 isoform 2
NM_001393781.1 NP_001380710.1 endophilin-B2 isoform 1

Gene Ontology

  • Biological Process
  • Cellular Component
Biological Process GO Annotation Evidence References Source
involved in postsynaptic neurotransmitter receptor internalization IDA
IDA: Inferred from direct assay
26776730 RGD
involved in postsynaptic neurotransmitter receptor internalization IEP
IEP: Inferred from expression pattern
26776730 RGD
involved in postsynaptic neurotransmitter receptor internalization IMP
IMP: Inferred from mutant phenotype
26776730 RGD
Cellular Component GO Annotation Evidence References Source
is active in glutamatergic synapse IDA
IDA: Inferred from direct assay
26776730 RGD
is active in glutamatergic synapse IMP
IMP: Inferred from mutant phenotype
26776730 RGD
is active in postsynaptic endocytic zone IDA
IDA: Inferred from direct assay
26776730 RGD
is active in postsynaptic endocytic zone IMP
IMP: Inferred from mutant phenotype
26776730 RGD
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

endophilin-B2

  • SH3 domain-containing GRB2-like protein B2

  • SH3-containing protein SH3GLB2

  • SH3-domain GRB2-like endophilin B2

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (1)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-RS12840 SH3GLB2 Human Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Sh3glb2 NCBI NCBI:56904