SH3GLB2 - SH3 domain containing GRB2 like, endophilin B2 Gene

Homo sapiens

Also known as RRIG1; PP6569; PP9455

Gene ID: 56904 | Gene type: protein coding

About SH3GLB2

Cytogenetic location: 9q34.11 Genomic coordinates (GRCh38): 9:129,007,036-129,028,331 (from NCBI)

This gene has 12 transcripts (splice variants), 274 orthologues and 12 paralogues. Ubiquitous expression in skin (RPKM 45.1), prostate (RPKM 29.7) and 25 other tissues.

Summary

Enables identical protein binding activity. Located in cytosol and nucleoplasm. [provided by Alliance of Genome Resources, Apr 2022]

SH3GLB2 Products(6)

mRNA	Protein	Name
NM_001287045.2	NP_001273974.1	endophilin-B2 isoform a
NM_001287046.2	NP_001273975.1	endophilin-B2 isoform b
NM_001369913.1	NP_001356842.1	endophilin-B2 isoform c
NM_001369914.1	NP_001356843.1	endophilin-B2 isoform d
NM_001369915.1	NP_001356844.1	endophilin-B2 isoform e
NM_020145.4	NP_064530.1	endophilin-B2 isoform b

SH3GLB2 Protein Structure

BAR

SH3_9

0
100
200
300
395 a.a.

Protein Preferred Names

Protein Names

endophilin-B2

SH3 domain-containing GRB2-like protein B2

Related Diseases

Diseases

Alias

Epidermolysis Bullosa Simplex 5b, With Muscular Dystrophy

Epidermolysis Bullosa Simplex With Muscular Dystrophy	Md-Ebs
Epidermolysis Bullosa Simplex And Limb-Girdle Muscular Dystrophy	EBS5B
Ebsmd	Mdebs
Limb-Girdle Muscular Dystrophy With Epidermolysis Bullosa Simplex	Ebs-Md
Epidermolysa Bullosa Simplex And Limb Girdle Muscular Dystrophy	Epidermolysa Bullosa Simplex With Muscular Dystrophy
Epidermolysis Bullosa Simplex - Limb Girdle Muscular Dystrophy	Ebs With Muscular Dystrophy
Muscular Dystrophy With Epidermolysis Bullosa Simplex	Epidermolysa Bullosa Simplex, With Muscular Dystrophy

Epidermolysis Bullosa, Junctional 5b, With Pyloric Atresia

Junctional Epidermolysis Bullosa With Pyloric Atresia	Carmi Syndrome
Epidermolysis Bullosa, Junctional, With Pyloric Atresia	Jeb-Pa
JEB5B	Epidermolysis Bullosa Junctionalis With Pyloric Atresia
Aplasia Cutis Congenita With Gastrointestinal Atresia	Epidermolysis Bullosa, Junctional, With Pyloric Atresia And Aplasia Cutis Congenita
Eb-Pa-Acc	Junctional Epidermolysis Bullosa-Pyloric Atresia Syndrome
Jeb With Pyloric Atresia	Epidermolysis Bullosa Letalis, With Pyloric Atresia
Pa-Jeb	Epidermolysis Bullosa With Pyloric Atresia

Diseases	Alias
Waldenstroem'S Macroglobulinemia	Waldenstroem'S Macroglobulinemia Waldenstroem'S Macroglobulinemia Macroglobulinemia Of Waldenstrom Lymphoplasmacytic Lymphoma With Igm Gammopathy Lymphoplasmacytic Lymphoma Waldenstroem'S Macroglobulinemia Waldenstroem'S Macroglobulinemia Macroglobulinemia Of Waldenstrom Lymphoplasmacytic Lymphoma With Igm Gammopathy Lymphoplasmacytic Lymphoma

Related Agents

Pre-clinical Phase

Bioactive Molecules (1)

Cat. No.	Product Name	Effect	Purity	Rare Diseases
HY-RS12840	SH3GLB2 Human Pre-designed siRNA Set A		/	Unkown

Orthologs Information

Species	Symbol	Source	ID
Canis familiaris	SH3GLB2	VGNC	VGNC:46128
Rattus norvegicus	SH3GLB2	RGD	RGD:1305886
Macaca mulatta	SH3GLB2	VGNC	VGNC:77207
Mus musculus	SH3GLB2	MGD	MGI:2385131
Felis catus	SH3GLB2	VGNC	VGNC:65110
Bos taurus	SH3GLB2	VGNC	VGNC:34576

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