TBC1D7-LOC100130357 - TBC1D7-LOC100130357 readthrough Gene
Species: Homo sapiens (human)
Gene Type: protein coding
Gene ID: 107080638
Summary
This locus represents naturally occurring readthrough transcription between the neighboring TBC1D7 (TBC1 domain family member 7) gene and downstream uncharacterized LOC100130357 on chromosome 6. Readthrough transcripts may encode the same protein as TBC1 domain family member 7 or may be candidates for nonsense-mediated mRNA decay (NMD). [provided by RefSeq, Jan 2016]
TBC1D7-LOC100130357 Products (1)
| mRNA | Protein | Name |
|---|---|---|
| NR_134872.2 |
| Molecular Function GO Annotation | Evidence | References | Source |
|---|---|---|---|
| enables GTPase activator activity |
IDA
IDA: Inferred from direct assay
|
17646400 | GOA |
| enables protein binding |
IPI
IPI: Inferred from physical interaction
|
17658474 | GOA |
| enables small GTPase binding |
IPI
IPI: Inferred from physical interaction
|
17646400 | GOA |
| Biological Process GO Annotation | Evidence | References | Source |
|---|---|---|---|
| involved in activation of GTPase activity |
IMP
IMP: Inferred from mutant phenotype
|
22795129 | GOA |
| involved in cellular response to starvation |
IDA
IDA: Inferred from direct assay
|
24529379 | GOA |
| involved in negative regulation of TOR signaling |
IDA
IDA: Inferred from direct assay
|
22795129 | GOA |
| involved in negative regulation of TOR signaling |
IMP
IMP: Inferred from mutant phenotype
|
22795129 | GOA |
| involved in negative regulation of TORC1 signaling |
IDA
IDA: Inferred from direct assay
|
24529379 | GOA |
| involved in negative regulation of cilium assembly |
IMP
IMP: Inferred from mutant phenotype
|
17646400 | GOA |
| involved in positive regulation of GTPase activity |
IDA
IDA: Inferred from direct assay
|
17646400 | GOA |
| involved in positive regulation of protein ubiquitination |
IDA
IDA: Inferred from direct assay
|
17658474 | GOA |
| involved in response to growth factor |
IMP
IMP: Inferred from mutant phenotype
|
22795129 | GOA |
| Cellular Component GO Annotation | Evidence | References | Source |
|---|---|---|---|
| part of TSC1-TSC2 complex |
IDA
IDA: Inferred from direct assay
|
24529379 | GOA |
| part of TSC1-TSC2 complex |
IPI
IPI: Inferred from physical interaction
|
22795129 | GOA |
| located in ciliary basal body |
IDA
IDA: Inferred from direct assay
|
17646400 | GOA |
| located in cytoplasmic vesicle |
IDA
IDA: Inferred from direct assay
|
17658474 | GOA |
| located in cytosol |
IDA
IDA: Inferred from direct assay
|
24529379 | GOA |
| is active in lysosomal membrane |
IDA
IDA: Inferred from direct assay
|
24529379 | GOA |
EXP: Inferred from Experiment
IDA: Inferred from direct assay
IPI: Inferred from physical interaction
IMP: Inferred from mutant phenotype
IGI: Inferred from genetic interaction
IEP: Inferred from expression pattern
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| Protein Preferred Names | Protein Names | |
|---|---|---|
|
TBC1 domain family member 7 |
|
TBC1D7-LOC100130357 Protein-protein interaction Information
|
Type
|
Protein Name | Protein ID | Interactor | Interactor Species | Interactor ID | Detection Method | References |
|---|---|---|---|---|---|---|---|
|
Intra
|
TBC1D7 | Q9P0N9 | TSC1 | Homo sapiens | Q92574 | 33436626 | |
|
Intra
|
TBC1D7 | Q9P0N9 | TSC1 | Homo sapiens | Q92574 | 33961781 | |
|
Intra
|
TBC1D7 | Q9P0N9 | TSC1 | Homo sapiens | Q92574 | 28514442 | |
|
Intra
|
TBC1D7 | Q9P0N9 | TSC1 | Homo sapiens | Q92574 | 33436626 | |
|
Intra
|
TBC1D7 | Q9P0N9 | RPGRIP1 | Homo sapiens | Q96KN7 | 25416956 | |
|
Intra
|
TBC1D7 | Q9P0N9 | KRT35 | Homo sapiens | Q92764 | 32296183 | |
|
Intra
|
TBC1D7 | Q9P0N9 | KRT35 | Homo sapiens | Q92764 | 32296183 | |
|
Intra
|
TBC1D7 | Q9P0N9 | MMADHC | Homo sapiens | Q9H3L0 | 32296183 | |
|
Intra
|
TBC1D7 | Q9P0N9 | MMADHC | Homo sapiens | Q9H3L0 | 32296183 | |
|
Intra
|
TBC1D7 | Q9P0N9 | LZTS1 | Homo sapiens | Q9Y250 | 32296183 | |
|
Intra
|
TBC1D7 | Q9P0N9 | LZTS1 | Homo sapiens | Q9Y250 | 32296183 | |
|
Intra
|
TBC1D7 | Q9P0N9 | LZTS1 | Homo sapiens | Q9Y250 | 32296183 | |
|
Intra
|
TBC1D7 | Q9P0N9 | SSNA1 | Homo sapiens | O43805 | 25416956 | |
|
Intra
|
TBC1D7 | Q9P0N9 | SSNA1 | Homo sapiens | O43805 | 32296183 | |
|
Intra
|
TBC1D7 | Q9P0N9 | SSNA1 | Homo sapiens | O43805 | 25416956 | |
|
Intra
|
TBC1D7 | Q9P0N9 | SSNA1 | Homo sapiens | O43805 | 25416956 | |
|
Intra
|
TBC1D7 | Q9P0N9 | SSNA1 | Homo sapiens | O43805 | 32296183 | |
|
Intra
|
TBC1D7 | Q9P0N9 | BLZF1 | Homo sapiens | Q9H2G9 | 25416956 | |
|
Intra
|
TBC1D7 | Q9P0N9 | BLZF1 | Homo sapiens | Q9H2G9 | 25416956 | |
|
Intra
|
TBC1D7 | Q9P0N9 | BLZF1 | Homo sapiens | Q9H2G9 | 32296183 | |
|
Intra
|
TBC1D7 | Q9P0N9 | BLZF1 | Homo sapiens | Q9H2G9 | 25416956 | |
|
Intra
|
TBC1D7 | Q9P0N9 | BLZF1 | Homo sapiens | Q9H2G9 | 32296183 | |
|
Intra
|
TBC1D7 | Q9P0N9 | MIPOL1 | Homo sapiens | Q8TD10 | 32296183 | |
|
Intra
|
TBC1D7 | Q9P0N9 | MIPOL1 | Homo sapiens | Q8TD10 | 32296183 | |
|
Intra
|
TBC1D7 | Q9P0N9 | BAG4 | Homo sapiens | O95429 | 27107012 | |
|
Intra
|
TBC1D7 | Q9P0N9 | BAG4 | Homo sapiens | O95429 | 32296183 | |
|
Intra
|
TBC1D7 | Q9P0N9 | BAG4 | Homo sapiens | O95429 | 27107012 | |
|
Intra
|
TBC1D7 | Q9P0N9 | BAG4 | Homo sapiens | O95429 | 32296183 | |
|
Intra
|
TBC1D7 | Q9P0N9 | XPA | Homo sapiens | P23025 | 32296183 | |
|
Intra
|
TBC1D7 | Q9P0N9 | XPA | Homo sapiens | P23025 | 32296183 | |
|
Intra
|
TBC1D7 | Q9P0N9 | TRAF4 | Homo sapiens | Q9BUZ4 | 32296183 | |
|
Intra
|
TBC1D7 | Q9P0N9 | TRAF4 | Homo sapiens | Q9BUZ4 | 27107012 | |
|
Intra
|
TBC1D7 | Q9P0N9 | TRAF4 | Homo sapiens | Q9BUZ4 | 27107012 | |
|
Intra
|
TBC1D7 | Q9P0N9 | TRAF4 | Homo sapiens | Q9BUZ4 | 25416956 | |
|
Intra
|
TBC1D7 | Q9P0N9 | TRAF4 | Homo sapiens | Q9BUZ4 | 32296183 | |
|
Intra
|
TBC1D7 | Q9P0N9 | INCA1 | Homo sapiens | Q0VD86 | 32296183 | |
|
Intra
|
TBC1D7 | Q9P0N9 | INCA1 | Homo sapiens | Q0VD86 | 32296183 | |
|
Intra
|
TBC1D7 | Q9P0N9 | TRIM62 | Homo sapiens | Q9BVG3 | 32296183 | |
|
Intra
|
TBC1D7 | Q9P0N9 | TRIM62 | Homo sapiens | Q9BVG3 | 32296183 | |
|
Intra
|
TBC1D7 | Q9P0N9 | LDOC1 | Homo sapiens | O95751 | 32296183 | |
|
Intra
|
TBC1D7 | Q9P0N9 | LDOC1 | Homo sapiens | O95751 | 25416956 | |
|
Intra
|
TBC1D7 | Q9P0N9 | LDOC1 | Homo sapiens | O95751 | 32296183 | |
|
Intra
|
TBC1D7 | Q9P0N9 | LZTS2 | Homo sapiens | Q9BRK4 | 25416956 | |
|
Intra
|
TBC1D7 | Q9P0N9 | KRT19 | Homo sapiens | P08727 | 25416956 | |
|
Intra
|
TBC1D7 | Q9P0N9 | KRT19 | Homo sapiens | P08727 | 32296183 | |
|
Intra
|
TBC1D7 | Q9P0N9 | KRT19 | Homo sapiens | P08727 | 32296183 | |
|
Intra
|
TBC1D7 | Q9P0N9 | HOOK1 | Homo sapiens | Q9UJC3 | 32296183 | |
|
Intra
|
TBC1D7 | Q9P0N9 | HOOK1 | Homo sapiens | Q9UJC3 | 32296183 | |
|
Intra
|
TBC1D7 | Q9P0N9 | HOOK1 | Homo sapiens | Q9UJC3 | 32296183 | |
|
Intra
|
TBC1D7 | Q9P0N9 | HOOK1 | Homo sapiens | Q9UJC3 | 25416956 | |
|
Intra
|
TBC1D7 | Q9P0N9 | SH3GLB2 | Homo sapiens | Q9NR46 | 32296183 | |
|
Intra
|
TBC1D7 | Q9P0N9 | SH3GLB2 | Homo sapiens | Q9NR46 | 32296183 | |
|
Intra
|
TBC1D7 | Q9P0N9 | KEAP1 | Homo sapiens | Q14145 | 32296183 | |
|
Intra
|
TBC1D7 | Q9P0N9 | KEAP1 | Homo sapiens | Q14145 | 32296183 | |
|
Intra
|
TBC1D7 | Q9P0N9 | PICK1 | Homo sapiens | Q9NRD5 | 32296183 | |
|
Intra
|
TBC1D7 | Q9P0N9 | PICK1 | Homo sapiens | Q9NRD5 | 32296183 |
Cross: Cross-species interaction
Intra: Intraspecies interaction