TRAF4 - TNF receptor associated factor 4 Gene

Also Known as CART1; MLN62; RNF83

Species: Homo sapiens

Gene Type: protein coding
Gene ID: 9618

About TRAF4

Cytogenetic location: 17q11.2 Genomic coordinates (GRCh38): 17:28,744,011-28,750,956 (from NCBI)

This gene has 16 transcripts (splice variants), 213 orthologues and 5 paralogues. Ubiquitous expression in duodenum (RPKM 13.1), small intestine (RPKM 10.0) and 24 other tissues.

Summary

This gene encodes a member of the TNF Receptor associated factor (TRAF) family. TRAF proteins are associated with, and mediate signal transduction from members of the TNF Receptor Superfamily. The encoded protein has been shown to interact with neurotrophin receptor, p75 (NTR/NTSR1), and negatively regulate NTR induced cell death and NF-kappa B activation. This protein has been found to bind to p47phox, a cytosolic regulatory factor included in a multi-protein complex known as NAD(P)H oxidase. This protein thus, is thought to be involved in the oxidative activation of MAPK8/JNK. Alternatively spliced transcript variants have been observed but the full-length nature of only one has been determined. [provided by RefSeq, Jul 2008]

TRAF4 Products (1)

mRNA Protein Name
NM_004295.4 NP_004286.2 TNF receptor-associated factor 4

Gene Ontology

  • Molecular Function
  • Biological Process
  • Cellular Component
Molecular Function GO Annotation Evidence References Source
enables WW domain binding IPI
IPI: Inferred from physical interaction
19937093 GOA
enables identical protein binding IPI
IPI: Inferred from physical interaction
24311986 GOA
enables protein binding IPI
IPI: Inferred from physical interaction
10514511 GOA
enables thioesterase binding IPI
IPI: Inferred from physical interaction
11279055 GOA
enables tumor necrosis factor receptor binding IPI
IPI: Inferred from physical interaction
11728344 GOA
enables ubiquitin protein ligase binding IPI
IPI: Inferred from physical interaction
11279055 GOA
Biological Process GO Annotation Evidence References Source
involved in positive regulation of JNK cascade IDA
IDA: Inferred from direct assay
16157600 GOA
involved in positive regulation of protein kinase activity IDA
IDA: Inferred from direct assay
16157600 GOA
Cellular Component GO Annotation Evidence References Source
located in cytoplasm IDA
IDA: Inferred from direct assay
16157600 GOA
located in nucleus IDA
IDA: Inferred from direct assay
18087216 GOA
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern

TRAF4 Protein Structure

zf-C3HC4

zf-C3HC4: Zinc finger, C3HC4 type (RING finger) (18 - 55)

zf-TRAF

zf-TRAF: TRAF-type zinc finger (102 - 156)

zf-TRAF

zf-TRAF: TRAF-type zinc finger (210 - 269)

MATH

MATH: MATH domain (329 - 464)

  • 0
  • 100
  • 200
  • 300
  • 400
  • 470 a.a.
Protein Preferred Names Protein Names

TNF receptor-associated factor 4

  • MLN 62

TRAF4 Protein-protein interaction Information

Type
Protein Name Protein ID Interactor Interactor Species Interactor ID Detection Method References
Intra
TRAF4 Q9BUZ4 KRT40 Homo sapiens Q6A162
Y2H Array
32296183
Intra
TRAF4 Q9BUZ4 KRT40 Homo sapiens Q6A162
Y2H Prey Pooling
25416956
Intra
TRAF4 Q9BUZ4 KRT40 Homo sapiens Q6A162
Y2H Prey Pooling
32296183
Intra
TRAF4 Q9BUZ4 KRT40 Homo sapiens Q6A162
Y2H Array
25416956
Intra
TRAF4 Q9BUZ4 HOMEZ Homo sapiens Q8IX15-3
Y2H Prey Pooling
25416956
Intra
TRAF4 Q9BUZ4 HOMEZ Homo sapiens Q8IX15-3
Y2H Array
25416956
Intra
TRAF4 Q9BUZ4 BCL6B Homo sapiens A8KA13
Y2H Array
25416956
Intra
TRAF4 Q9BUZ4 TP53BP2 Homo sapiens Q13625-3
Validated Y2H
25416956
Intra
TRAF4 Q9BUZ4 TP53BP2 Homo sapiens Q13625-3
Y2H Prey Pooling
25416956
Intra
TRAF4 Q9BUZ4 NPIPA7 Homo sapiens E9PJI5
Validated Y2H
25416956
Intra
TRAF4 Q9BUZ4 UBE2I Homo sapiens Q7KZS0
Y2H Array
32296183
Intra
TRAF4 Q9BUZ4 UBE2I Homo sapiens Q7KZS0
Y2H Prey Pooling
32296183
Intra
TRAF4 Q9BUZ4 ZNF3 Homo sapiens Q86U76
Y2H Array
25416956
Intra
TRAF4 Q9BUZ4 REXO1L1P Homo sapiens Q8IX06
Y2H Array
25416956
Intra
TRAF4 Q9BUZ4 REXO1L1P Homo sapiens Q8IX06
Y2H Prey Pooling
25416956
Intra
TRAF4 Q9BUZ4 UBL4B Homo sapiens Q8N7F7
Y2H Prey Pooling
32296183
Intra
TRAF4 Q9BUZ4 UBL4B Homo sapiens Q8N7F7
Y2H Array
31515488
Intra
TRAF4 Q9BUZ4 UBL4B Homo sapiens Q8N7F7
Y2H Array
32296183
Intra
TRAF4 Q9BUZ4 UBL4B Homo sapiens Q8N7F7
Y2H Array
25416956
Intra
TRAF4 Q9BUZ4 EXOC7 Homo sapiens Q96BU6
Y2H Prey Pooling
25416956
Intra
TRAF4 Q9BUZ4 EXOC7 Homo sapiens Q96BU6
Y2H Array
25416956
Intra
TRAF4 Q9BUZ4 EXOC7 Homo sapiens Q96BU6
Validated Y2H
25416956
Intra
TRAF4 Q9BUZ4 DNM2 Homo sapiens P50570-2
Validated Y2H
32814053
Intra
TRAF4 Q9BUZ4 DNM2 Homo sapiens P50570-2
Y2H Pooling
32814053
Intra
TRAF4 Q9BUZ4 DNM2 Homo sapiens P50570-2
Y2H Array
32814053
Intra
TRAF4 Q9BUZ4 GOLGA6A Homo sapiens Q9NYA3
Y2H Array
32296183
Intra
TRAF4 Q9BUZ4 GOLGA6A Homo sapiens Q9NYA3
Y2H Prey Pooling
32296183
Intra
TRAF4 Q9BUZ4 GOLGA6A Homo sapiens Q9NYA3
Validated Y2H
32296183
Cross
TRAF4 Q9BUZ4 q9e7p0_9flav Dengue virus 2 Q9E7P0
Y2H Array
22014111
Intra
TRAF4 Q9BUZ4 NHERF2 Homo sapiens Q15599
Y2H Array
32296183
Intra
TRAF4 Q9BUZ4 BANP Homo sapiens Q8N9N5-2
Y2H Prey Pooling
32296183
Intra
TRAF4 Q9BUZ4 BANP Homo sapiens Q8N9N5-2
Y2H Array
32296183
Intra
TRAF4 Q9BUZ4 PCSK5 Homo sapiens Q92824-2
Y2H Prey Pooling
32296183
Intra
TRAF4 Q9BUZ4 PCSK5 Homo sapiens Q92824-2
Y2H Array
32296183
Intra
TRAF4 Q9BUZ4 KRT36 Homo sapiens O76013-2
Y2H Array
32296183
Intra
TRAF4 Q9BUZ4 KRT36 Homo sapiens O76013-2
Y2H Prey Pooling
32296183
Intra
TRAF4 Q9BUZ4 ACTMAP Homo sapiens Q5BKX5-3
Y2H Array
32296183
Intra
TRAF4 Q9BUZ4 ACTMAP Homo sapiens Q5BKX5-3
Y2H Prey Pooling
32296183
Intra
TRAF4 Q9BUZ4 DISC1 Homo sapiens Q9NRI5-2
Y2H Prey Pooling
32296183
Intra
TRAF4 Q9BUZ4 DISC1 Homo sapiens Q9NRI5-2
Validated Y2H
32296183
Intra
TRAF4 Q9BUZ4 DISC1 Homo sapiens Q9NRI5-2
Y2H Array
32296183
Intra
TRAF4 Q9BUZ4 PLEKHA7 Homo sapiens Q6IQ23-2
Y2H Prey Pooling
32296183
Intra
TRAF4 Q9BUZ4 PLEKHA7 Homo sapiens Q6IQ23-2
Y2H Array
32296183
Intra
TRAF4 Q9BUZ4 ZNF177 Homo sapiens Q13360-2
Y2H Prey Pooling
32296183
Intra
TRAF4 Q9BUZ4 ZNF177 Homo sapiens Q13360-2
Y2H Array
32296183
Intra
TRAF4 Q9BUZ4 CEP85 Homo sapiens Q6P2H3-3
Y2H Prey Pooling
32296183
Intra
TRAF4 Q9BUZ4 CEP85 Homo sapiens Q6P2H3-3
Y2H Array
32296183
Intra
TRAF4 Q9BUZ4 EYA2 Homo sapiens O00167-2
Y2H Prey Pooling
32296183
Intra
TRAF4 Q9BUZ4 EYA2 Homo sapiens O00167-2
Y2H Array
32296183
Intra
TRAF4 Q9BUZ4 POLR2J3 Homo sapiens Q9H1A7
Y2H Prey Pooling
32296183
Intra
TRAF4 Q9BUZ4 POLR2J3 Homo sapiens Q9H1A7
Validated Y2H
32296183
Intra
TRAF4 Q9BUZ4 POLR2J3 Homo sapiens Q9H1A7
Y2H Array
32296183
Intra
TRAF4 Q9BUZ4 EZHIP Homo sapiens Q86X51
Y2H Prey Pooling
32296183
Intra
TRAF4 Q9BUZ4 EZHIP Homo sapiens Q86X51
Y2H Array
32296183
Intra
TRAF4 Q9BUZ4 TYK2 Homo sapiens P29597
Y2H Prey Pooling
25416956
Intra
TRAF4 Q9BUZ4 TYK2 Homo sapiens P29597
Validated Y2H
25416956
Intra
TRAF4 Q9BUZ4 ZNF3 Homo sapiens P17036
Y2H Array
25416956
Intra
TRAF4 Q9BUZ4 BACH2 Homo sapiens Q9BYV9
Validated Y2H
32296183
Intra
TRAF4 Q9BUZ4 BACH2 Homo sapiens Q9BYV9
Y2H Prey Pooling
32296183
Intra
TRAF4 Q9BUZ4 BACH2 Homo sapiens Q9BYV9
Y2H Array
32296183
Intra
TRAF4 Q9BUZ4 ZNF275 Homo sapiens Q9NSD4
Y2H Prey Pooling
32296183
Intra
TRAF4 Q9BUZ4 ZNF275 Homo sapiens Q9NSD4
Validated Y2H
32296183
Intra
TRAF4 Q9BUZ4 ZNF275 Homo sapiens Q9NSD4
Y2H Array
32296183
Intra
TRAF4 Q9BUZ4 ZMYM5 Homo sapiens Q9UJ78-2
Validated Y2H
32296183
Intra
TRAF4 Q9BUZ4 ZMYM5 Homo sapiens Q9UJ78-2
Y2H Array
32296183
Intra
TRAF4 Q9BUZ4 ZMYM5 Homo sapiens Q9UJ78-2
Y2H Prey Pooling
32296183
Intra
TRAF4 Q9BUZ4 DPEP2NB Homo sapiens A0A0U1RQF7
Y2H Prey Pooling
32296183
Intra
TRAF4 Q9BUZ4 DPEP2NB Homo sapiens A0A0U1RQF7
Y2H Array
32296183
Intra
TRAF4 Q9BUZ4 DTX3 Homo sapiens Q8N9I9
Y2H Prey Pooling
32296183
Intra
TRAF4 Q9BUZ4 DTX3 Homo sapiens Q8N9I9
Y2H Array
22493164
Intra
TRAF4 Q9BUZ4 DTX3 Homo sapiens Q8N9I9
Y2H Array
32296183
Intra
TRAF4 Q9BUZ4 RNF4 Homo sapiens P78317
Y2H Array
32296183
Intra
TRAF4 Q9BUZ4 RNF4 Homo sapiens P78317
Y2H Prey Pooling
32296183
Intra
TRAF4 Q9BUZ4 GORASP1 Homo sapiens Q9BQQ3
Y2H Prey Pooling
32296183
Intra
TRAF4 Q9BUZ4 GORASP1 Homo sapiens Q9BQQ3
Y2H Array
32296183
Intra
TRAF4 Q9BUZ4 TOR1A Homo sapiens O14656-2
Y2H Pooling
32814053
Intra
TRAF4 Q9BUZ4 TOR1A Homo sapiens O14656-2
Validated Y2H
32814053
Intra
TRAF4 Q9BUZ4 TOR1A Homo sapiens O14656-2
Y2H Array
32814053
Intra
TRAF4 Q9BUZ4 VPS52 Homo sapiens Q8N1B4
Y2H Array
32296183
Intra
TRAF4 Q9BUZ4 VPS52 Homo sapiens Q8N1B4
Y2H Prey Pooling
32296183
Intra
TRAF4 Q9BUZ4 TPP1 Homo sapiens O14773
Validated Y2H
32814053
Intra
TRAF4 Q9BUZ4 TPP1 Homo sapiens O14773
Y2H Array
32814053
Intra
TRAF4 Q9BUZ4 TPP1 Homo sapiens O14773
Y2H Pooling
32814053
Intra
TRAF4 Q9BUZ4 ZC3H12C Homo sapiens Q9C0D7
Validated Y2H
32296183
Intra
TRAF4 Q9BUZ4 ZC3H12C Homo sapiens Q9C0D7
Y2H Array
32296183
Intra
TRAF4 Q9BUZ4 ZC3H12C Homo sapiens Q9C0D7
Y2H Prey Pooling
32296183
Intra
TRAF4 Q9BUZ4 PLAGL2 Homo sapiens Q9UPG8
Validated Y2H
32296183
Intra
TRAF4 Q9BUZ4 PLAGL2 Homo sapiens Q9UPG8
Y2H Array
32296183
Intra
TRAF4 Q9BUZ4 PLAGL2 Homo sapiens Q9UPG8
Y2H Prey Pooling
32296183
Intra
TRAF4 Q9BUZ4 TBC1D7 Homo sapiens Q9P0N9
Validated Y2H
32296183
Intra
TRAF4 Q9BUZ4 TBC1D7 Homo sapiens Q9P0N9
Y2H Prey Pooling
25416956
Intra
TRAF4 Q9BUZ4 TBC1D7 Homo sapiens Q9P0N9
Y2H Array
31515488
Intra
TRAF4 Q9BUZ4 TBC1D7 Homo sapiens Q9P0N9
Validated Y2H
25416956
Intra
TRAF4 Q9BUZ4 DNM2 Homo sapiens P50570
Y2H Prey Pooling
32296183
Intra
TRAF4 Q9BUZ4 DNM2 Homo sapiens P50570
Y2H Array
32296183
Intra
TRAF4 Q9BUZ4 QARS1 Homo sapiens P47897
Y2H Array
25416956
Intra
TRAF4 Q9BUZ4 QARS1 Homo sapiens P47897
Y2H Prey Pooling
25416956
Intra
TRAF4 Q9BUZ4 SF3B4 Homo sapiens Q15427
Y2H Prey Pooling
32296183
Intra
TRAF4 Q9BUZ4 SF3B4 Homo sapiens Q15427
Y2H Array
32296183
Intra
TRAF4 Q9BUZ4 UBL4A Homo sapiens P11441
Validated Y2H
25416956
Intra
TRAF4 Q9BUZ4 UBL4A Homo sapiens P11441
Y2H Array
25416956
Intra
TRAF4 Q9BUZ4 UBL4A Homo sapiens P11441
Y2H Array
32296183
Intra
TRAF4 Q9BUZ4 UBL4A Homo sapiens P11441
Y2H Prey Pooling
25416956
Intra
TRAF4 Q9BUZ4 UBL4A Homo sapiens P11441
Y2H Prey Pooling
32296183
Intra
TRAF4 Q9BUZ4 BYSL Homo sapiens Q13895
Y2H
21516116
Intra
TRAF4 Q9BUZ4 BYSL Homo sapiens Q13895
Y2H Prey Pooling
25416956
Intra
TRAF4 Q9BUZ4 BYSL Homo sapiens Q13895
Validated Y2H
25416956
Intra
TRAF4 Q9BUZ4 BYSL Homo sapiens Q13895
Y2H Array
25416956
Intra
TRAF4 Q9BUZ4 PSMC3 Homo sapiens P17980
Y2H Array
32296183
Intra
TRAF4 Q9BUZ4 PSMC3 Homo sapiens P17980
Y2H Prey Pooling
32296183
Intra
TRAF4 Q9BUZ4 ZBTB26 Homo sapiens Q9HCK0
Validated Y2H
32296183
Intra
TRAF4 Q9BUZ4 ZBTB26 Homo sapiens Q9HCK0
Y2H Prey Pooling
32296183
Intra
TRAF4 Q9BUZ4 ZBTB26 Homo sapiens Q9HCK0
Y2H Array
32296183
Intra
TRAF4 Q9BUZ4 POLR2J Homo sapiens P52435
Y2H Prey Pooling
32296183
Intra
TRAF4 Q9BUZ4 POLR2J Homo sapiens P52435
Y2H Array
32296183
Intra
TRAF4 Q9BUZ4 NCF1 Homo sapiens P14598
Y2H Prey Pooling
32296183
Intra
TRAF4 Q9BUZ4 NCF1 Homo sapiens P14598
Y2H Array
32296183
Intra
TRAF4 Q9BUZ4 ZNF620 Homo sapiens Q6ZNG0
Y2H Prey Pooling
32296183
Intra
TRAF4 Q9BUZ4 ZNF620 Homo sapiens Q6ZNG0
Y2H Array
32296183
Intra
TRAF4 Q9BUZ4 ZRANB1 Homo sapiens Q9UGI0
Validated Y2H
32296183
Intra
TRAF4 Q9BUZ4 ZRANB1 Homo sapiens Q9UGI0
Y2H Array
32296183
Intra
TRAF4 Q9BUZ4 ZRANB1 Homo sapiens Q9UGI0
Y2H Prey Pooling
32296183
Intra
TRAF4 Q9BUZ4 TAX1BP1 Homo sapiens Q86VP1
Y2H Prey Pooling
32296183
Intra
TRAF4 Q9BUZ4 TAX1BP1 Homo sapiens Q86VP1
Y2H Array
32296183
Intra
TRAF4 Q9BUZ4 ZNF835 Homo sapiens Q9Y2P0
Validated Y2H
32296183
Intra
TRAF4 Q9BUZ4 GOLGA6L9 Homo sapiens A6NEM1
Y2H Prey Pooling
32296183
Intra
TRAF4 Q9BUZ4 GOLGA6L9 Homo sapiens A6NEM1
Y2H Array
32296183
Intra
TRAF4 Q9BUZ4 GOLGA2 Homo sapiens Q08379
Y2H Array
32296183
Intra
TRAF4 Q9BUZ4 GOLGA2 Homo sapiens Q08379
Y2H Prey Pooling
32296183
Intra
TRAF4 Q9BUZ4 UBA1 Homo sapiens P22314
Validated Y2H
32814053
Intra
TRAF4 Q9BUZ4 UBA1 Homo sapiens P22314
Y2H Array
32814053
Intra
TRAF4 Q9BUZ4 UBA1 Homo sapiens P22314
Y2H Pooling
32814053
Intra
TRAF4 Q9BUZ4 KDM1A Homo sapiens O60341
Y2H
23455924
Intra
TRAF4 Q9BUZ4 SPDL1 Homo sapiens Q96EA4
Y2H Array
25416956
Intra
TRAF4 Q9BUZ4 SPDL1 Homo sapiens Q96EA4
Validated Y2H
25416956
Intra
TRAF4 Q9BUZ4 TRIM27 Homo sapiens P14373
Y2H Array
32296183
Intra
TRAF4 Q9BUZ4 TRIM27 Homo sapiens P14373
Y2H Prey Pooling
32296183
Intra
TRAF4 Q9BUZ4 ISYNA1 Homo sapiens Q9NPH2
Y2H Array
25416956
Intra
TRAF4 Q9BUZ4 ISYNA1 Homo sapiens Q9NPH2
Y2H Prey Pooling
25416956
Intra
TRAF4 Q9BUZ4 MRPL28 Homo sapiens Q13084
Y2H Array
31515488
Intra
TRAF4 Q9BUZ4 MRPL28 Homo sapiens Q13084
Validated Y2H
25416956
Intra
TRAF4 Q9BUZ4 GORASP2 Homo sapiens Q9H8Y8
Y2H Array
25416956
Intra
TRAF4 Q9BUZ4 GORASP2 Homo sapiens Q9H8Y8
Y2H Array
29892012
Intra
TRAF4 Q9BUZ4 GORASP2 Homo sapiens Q9H8Y8
Validated Y2H
25416956
Intra
TRAF4 Q9BUZ4 KANSL1 Homo sapiens Q7Z3B3
Y2H Prey Pooling
25416956
Intra
TRAF4 Q9BUZ4 HMG20A Homo sapiens Q9NP66
Y2H Array
32296183
Intra
TRAF4 Q9BUZ4 HMG20A Homo sapiens Q9NP66
Validated Y2H
32296183
Intra
TRAF4 Q9BUZ4 HMG20A Homo sapiens Q9NP66
Y2H Prey Pooling
32296183
Intra
TRAF4 Q9BUZ4 HOXA1 Homo sapiens P49639
Y2H Prey Pooling
32296183
Intra
TRAF4 Q9BUZ4 HOXA1 Homo sapiens P49639
Y2H Array
32296183
Intra
TRAF4 Q9BUZ4 ABI3 Homo sapiens Q9P2A4
Validated Y2H
32296183
Intra
TRAF4 Q9BUZ4 ABI3 Homo sapiens Q9P2A4
Y2H Prey Pooling
32296183
Intra
TRAF4 Q9BUZ4 ABI3 Homo sapiens Q9P2A4
Y2H Array
32296183
Intra
TRAF4 Q9BUZ4 WWP1 Homo sapiens Q9H0M0
Validated Y2H
25416956
Intra
TRAF4 Q9BUZ4 BEGAIN Homo sapiens Q9BUH8
Y2H Prey Pooling
32296183
Intra
TRAF4 Q9BUZ4 BEGAIN Homo sapiens Q9BUH8
Y2H Array
32296183
Intra
TRAF4 Q9BUZ4 BAHD1 Homo sapiens Q8TBE0
Y2H Prey Pooling
25416956
Intra
TRAF4 Q9BUZ4 WWP2 Homo sapiens O00308
Y2H Prey Pooling
25416956
Intra
TRAF4 Q9BUZ4 WWP2 Homo sapiens O00308
Y2H Prey Pooling
32296183
Intra
TRAF4 Q9BUZ4 WWP2 Homo sapiens O00308
Y2H Array
32296183
Intra
TRAF4 Q9BUZ4 FBXL18 Homo sapiens Q96D16
Validated Y2H
25416956
Intra
TRAF4 Q9BUZ4 FBXL18 Homo sapiens Q96D16
Y2H Array
25416956
Intra
TRAF4 Q9BUZ4 FBXL18 Homo sapiens Q96D16
Y2H Prey Pooling
25416956
Intra
TRAF4 Q9BUZ4 BANP Homo sapiens Q8N9N5
Y2H Prey Pooling
25416956
Intra
TRAF4 Q9BUZ4 ZNF581 Homo sapiens Q9P0T4
Y2H Array
25416956
Intra
TRAF4 Q9BUZ4 ZNF581 Homo sapiens Q9P0T4
Validated Y2H
32296183
Intra
TRAF4 Q9BUZ4 ZNF581 Homo sapiens Q9P0T4
Y2H Prey Pooling
25416956
Intra
TRAF4 Q9BUZ4 CARF Homo sapiens Q8N187
Y2H Array
32814053
Intra
TRAF4 Q9BUZ4 CARF Homo sapiens Q8N187
Y2H Pooling
32814053
Intra
TRAF4 Q9BUZ4 CARF Homo sapiens Q8N187
Validated Y2H
32814053
Intra
TRAF4 Q9BUZ4 ATOSB Homo sapiens Q7L5A3
Y2H Array
29892012
Intra
TRAF4 Q9BUZ4 ATOSB Homo sapiens Q7L5A3
Y2H
21516116
Intra
TRAF4 Q9BUZ4 HEY2 Homo sapiens Q9UBP5
Validated Y2H
32296183
Intra
TRAF4 Q9BUZ4 NOS1AP Homo sapiens O75052
Validated Y2H
25416956
Intra
TRAF4 Q9BUZ4 NOS1AP Homo sapiens O75052
Y2H Array
25416956
Intra
TRAF4 Q9BUZ4 PICK1 Homo sapiens Q9NRD5
Y2H Prey Pooling
32296183
Intra
TRAF4 Q9BUZ4 PICK1 Homo sapiens Q9NRD5
Validated Y2H
32296183
Intra
TRAF4 Q9BUZ4 PICK1 Homo sapiens Q9NRD5
Y2H Array
32296183
Intra
TRAF4 Q9BUZ4 SUMO1 Homo sapiens P63165
Y2H Array
25416956
Intra
TRAF4 Q9BUZ4 SUMO1 Homo sapiens P63165
Validated Y2H
25416956
Intra
TRAF4 Q9BUZ4 ALKBH4 Homo sapiens Q9NXW9
Y2H Array
31515488
Intra
TRAF4 Q9BUZ4 ALKBH4 Homo sapiens Q9NXW9
Y2H Prey Pooling
25416956
Intra
TRAF4 Q9BUZ4 ALKBH4 Homo sapiens Q9NXW9
Validated Y2H
25416956
Intra
TRAF4 Q9BUZ4 ALKBH4 Homo sapiens Q9NXW9
Y2H Array
25416956
Intra
TRAF4 Q9BUZ4 UBQLN2 Homo sapiens Q9UHD9
Y2H Prey Pooling
32296183
Intra
TRAF4 Q9BUZ4 UBQLN2 Homo sapiens Q9UHD9
Validated Y2H
32296183
Intra
TRAF4 Q9BUZ4 UBQLN2 Homo sapiens Q9UHD9
Y2H Array
32296183
Intra
TRAF4 Q9BUZ4 KRT31 Homo sapiens Q15323
Y2H Array
32296183
Intra
TRAF4 Q9BUZ4 KRT31 Homo sapiens Q15323
Y2H Prey Pooling
32296183
Intra
TRAF4 Q9BUZ4 KRT31 Homo sapiens Q15323
Y2H Array
25416956
Intra
TRAF4 Q9BUZ4 RAD54L2 Homo sapiens Q9Y4B4
Validated Y2H
32296183
Intra
TRAF4 Q9BUZ4 RAD54L2 Homo sapiens Q9Y4B4
Y2H Array
32296183
Intra
TRAF4 Q9BUZ4 RAD54L2 Homo sapiens Q9Y4B4
Y2H Prey Pooling
32296183
Intra
TRAF4 Q9BUZ4 SMURF1 Homo sapiens Q9HCE7-2
Y2H
19937093
Intra
TRAF4 Q9BUZ4 SMURF1 Homo sapiens Q9HCE7-2
Pull Down
19937093
Cross
TRAF4 Q9BUZ4 Ngfr Rattus norvegicus P07174
Pull Down
10514511
Cross
TRAF4 Q9BUZ4 Ngfr Rattus norvegicus P07174
Anti Tag CoIP
10514511
Cross: Cross-species interaction Intra: Intraspecies interaction

TRAF4 Antibodies

Cat. No. Product Name Application Reactivity
HY-P83063 TRAF4 Antibody (YA2808) WB, ICC/IF, FC Human, Mouse

Related Diseases

Diseases Alias
Lung Cancer

  • Lung Carcinoma

  • Non-Small Cell Lung Carcinoma

  • Lung Cancer, Susceptibility To

  • Lung Cancer, Protection Against

  • Adenocarcinoma Of Lung, Somatic

  • Adenocarcinoma Of Lung, Response To Tyrosine Kinase Inhibitor In

  • Nonsmall Cell Lung Cancer

  • Lung Neoplasm

  • Carcinoma Of Lung

  • Lung Non-Small Cell Carcinoma

  • Non-Small Cell Lung Cancer

  • Nsclc

  • Lung Neoplasms

  • Malignant Neoplasm Of Lung

  • Alveolar Cell Carcinoma

  • Nonsmall Cell Lung Cancer, Somatic

  • Nonsmall Cell Lung Cancer, Response To Tyrosine Kinase Inhibitor In

  • Nonsmall Cell Lung Cancer, Susceptibility To

  • Lung Cancer, Somatic

  • Lung Cancer, Resistance To

  • Cancer Of Lung

  • Cancer Of Bronchus

  • Cancer Of The Lung

  • Lung Malignancies

  • Lung Malignant Tumors

  • Malignant Lung Tumor

  • Malignant Tumor Of Lung

  • Pulmonary Cancer

  • Pulmonary Carcinoma

  • Pulmonary Neoplasms

  • Respiratory Carcinoma

  • LNCR

  • Adenocarcinoma Of Lung

  • Neoplasm Of Lung

  • Cancer Lung

  • Carcinoma Non-Small Cell Lung

  • Carcinoma, Non-Small-Cell Lung

  • Lung Cancers

  • Lung Carcinomas

  • Cancer, Lung

  • Cancer, Lung, Non-Small Cell

  • Primary Malignant Neoplasm Of Lung

  • Bronchioloalveolar Adenocarcinoma
Intraneural Perineurioma
Breast Cancer

  • Breast Carcinoma

  • Male Breast Cancer

  • Breast Cancer, Familial

  • Malignant Neoplasm Of Breast

  • Breast Cancer, Susceptibility To

  • Breast Cancer, Early-Onset

  • Malignant Tumor Of Breast

  • Carcinoma Of Male Breast

  • Breast Cancer, Invasive Ductal

  • Breast Cancer, Protection Against

  • Breast Cancer, Somatic

  • Breast Cancer, Male

  • Breast Cancer, Lobular, Somatic

  • Breast Tumor

  • Mammary Cancer

  • Mammary Tumor

  • Malignant Neoplasm Of Male Breast

  • Mammary Carcinoma

  • Male Breast Carcinoma

  • Familial Cancer Of Breast

  • Invasive Ductal Breast Carcinoma

  • Breast Cancer Susceptibility

  • Breast Cancer, Male, Susceptibility To

  • Breast Cancer, Early-Onset, Susceptibility To

  • Malignant Tumor Of The Breast

  • Mammary Neoplasm

  • Primary Breast Cancer

  • Neoplasm Of Male Breast

  • Carcinoma Of Breast

  • Breast Cancer In Men

  • Familial Breast Cancer

  • Cancer Of Breast

  • BC

  • Breast Cancer Familial

  • Breast Cancer Familial Male

  • Breast Cancer, Familial Male

  • Breast Male Carcinoma

  • Breast Neoplasms

  • Breast Neoplasms, Male

  • Mammary Tumors

  • Mammary Carcinomas

  • Cancer, Breast

  • Cancer, Breast, Susceptibility

  • Invasive Breast Ductal Carcinoma

  • Breast Neoplasm

  • Susceptibility To Breast Cancer

  • Mammary Neoplasms

  • Animal Mammary Neoplasms

  • Primary Malignant Neoplasm Of Breast

  • Infiltrating Ductal Carcinoma Of Breast

  • Infiltrating Duct Carcinoma Of Unspecified Site

  • Infiltrating Ductular Carcinoma Of Unspecified Site

  • Invasive Breast Carcinoma Of No Special Type

  • Microinvasive Carcinoma Of Breast

  • Carcinoma With Apocrine Differentiation
Diseases Alias
Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (3)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-RS14973 TRAF4 Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS21068 Traf4 Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS27585 Traf4 Rat Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Felis catus TRAF4 VGNC VGNC:66500
Mus musculus TRAF4 MGD MGI:1202880
Canis familiaris TRAF4 VGNC VGNC:47768
Macaca mulatta TRAF4 VGNC VGNC:78643
Bos taurus TRAF4 VGNC VGNC:36276
Rattus norvegicus TRAF4 RGD RGD:1306708
Others TRAF4 NCBI