ZBTB26 - zinc finger and BTB domain containing 26 Gene

Also Known as ZNF481; bioref

Species: Homo sapiens

Gene Type: protein coding
Gene ID: 57684

Summary

Enables identical protein binding activity and sequence-specific double-stranded DNA binding activity. Predicted to be involved in negative regulation of transcription by RNA polymerase II; regulation of cytokine production; and regulation of immune system process. Predicted to be located in nucleus. Predicted to be active in nucleoplasm. [provided by Alliance of Genome Resources, Jul 2025]
Ubiquitous expression in testis (RPKM 7.0), ovary (RPKM 4.9) and 25 other tissues.

ZBTB26 Products (3)

mRNA Protein Name
NM_001304363.2 NP_001291292.1 zinc finger and BTB domain-containing protein 26
NM_001304364.2 NP_001291293.1 zinc finger and BTB domain-containing protein 26
NM_020924.4 NP_065975.1 zinc finger and BTB domain-containing protein 26

Gene Ontology

  • Molecular Function
Molecular Function GO Annotation Evidence References Source
enables identical protein binding IPI
IPI: Inferred from physical interaction
25416956 GOA
enables protein binding IPI
IPI: Inferred from physical interaction
25416956 GOA
enables sequence-specific double-stranded DNA binding IDA
IDA: Inferred from direct assay
28473536 GOA
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern

ZBTB26 Protein-protein interaction Information

Type
Protein Name Protein ID Interactor Interactor Species Interactor ID Detection Method References
Intra
ZBTB26 Q9HCK0 SUMO1P1 Homo sapiens G2XKQ0
Y2H Array
25416956
Intra
ZBTB26 Q9HCK0 MORF4L1 Homo sapiens Q9UBU8-2
Validated Y2H
32296183
Intra
ZBTB26 Q9HCK0 HEL164 Homo sapiens V9HWH0
Y2H Prey Pooling
25416956
Intra
ZBTB26 Q9HCK0 HEL164 Homo sapiens V9HWH0
Validated Y2H
25416956
Intra
ZBTB26 Q9HCK0 HEL164 Homo sapiens V9HWH0
Y2H Array
25416956
Intra
ZBTB26 Q9HCK0 ZBTB12 Homo sapiens Q9Y330
Validated Y2H
32296183
Intra
ZBTB26 Q9HCK0 ZMYM5 Homo sapiens Q9UJ78-2
Validated Y2H
32296183
Intra
ZBTB26 Q9HCK0 ZMYM5 Homo sapiens Q9UJ78-2
Y2H Array
32296183
Intra
ZBTB26 Q9HCK0 ZMYM5 Homo sapiens Q9UJ78-2
Y2H Prey Pooling
32296183
Intra
ZBTB26 Q9HCK0 RNF4 Homo sapiens P78317
Y2H Prey Pooling
32296183
Intra
ZBTB26 Q9HCK0 RNF4 Homo sapiens P78317
Y2H Array
32296183
Intra
ZBTB26 Q9HCK0 SUMO1 Homo sapiens P63165
Y2H Array
25416956
Intra
ZBTB26 Q9HCK0 ZBTB26 Homo sapiens Q9HCK0
Y2H Prey Pooling
32296183
Intra
ZBTB26 Q9HCK0 ZBTB26 Homo sapiens Q9HCK0
Complementation
32296183
Intra
ZBTB26 Q9HCK0 ZBTB26 Homo sapiens Q9HCK0
Validated Y2H
32296183
Intra
ZBTB26 Q9HCK0 ZBTB26 Homo sapiens Q9HCK0
Y2H Array
25416956
Intra
ZBTB26 Q9HCK0 SUMO1 Homo sapiens P63165
Validated Y2H
25416956
Intra
ZBTB26 Q9HCK0 ZBTB26 Homo sapiens Q9HCK0
Y2H Array
32296183
Intra
ZBTB26 Q9HCK0 GIPC2 Homo sapiens Q8TF65
Y2H Prey Pooling
25416956
Intra
ZBTB26 Q9HCK0 GIPC2 Homo sapiens Q8TF65
Validated Y2H
25416956
Intra
ZBTB26 Q9HCK0 DAXX Homo sapiens Q9UER7
Validated Y2H
32296183
Intra
ZBTB26 Q9HCK0 UBE2I Homo sapiens P63279
Y2H Prey Pooling
25416956
Intra
ZBTB26 Q9HCK0 UBE2I Homo sapiens P63279
Y2H Array
25416956
Intra
ZBTB26 Q9HCK0 RAD54L2 Homo sapiens Q9Y4B4
Validated Y2H
32296183
Intra
ZBTB26 Q9HCK0 RAD54L2 Homo sapiens Q9Y4B4
Y2H Prey Pooling
32296183
Intra
ZBTB26 Q9HCK0 RAD54L2 Homo sapiens Q9Y4B4
Y2H Array
32296183
Cross: Cross-species interaction Intra: Intraspecies interaction

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (9)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-RS15968 ZBTB20 Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS15964 ZBTB16 Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS15967 ZBTB2 Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS15969 ZBTB24 Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS15977 ZBTB46 Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS18204 Zbtb16 Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS19758 Zbtb2 Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS24681 Zbtb16 Rat Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS26255 Zbtb2 Rat Pre-designed siRNA Set A Pre-designed Set / Unkown