ZBTB12 - zinc finger and BTB domain containing 12 Gene

Also Known as G10; Bat9; NG35; D6S59E; C6orf46

Species: Homo sapiens

Gene Type: protein coding
Gene ID: 221527

About ZBTB12

This gene has 1 transcript (splice variant), 1 gene allele, 158 orthologues and 28 paralogues. Ubiquitous expression in ovary (RPKM 4.1), endometrium (RPKM 1.9) and 23 other tissues.

Summary

Enables sequence-specific double-stranded DNA binding activity. Predicted to be involved in regulation of transcription by RNA polymerase II. Located in nucleoplasm. [provided by Alliance of Genome Resources, Apr 2022]

ZBTB12 Products (1)

mRNA Protein Name
NM_181842.3 NP_862825.1 zinc finger and BTB domain-containing protein 12

Gene Ontology

  • Molecular Function
Molecular Function GO Annotation Evidence References Source
enables protein binding IPI
IPI: Inferred from physical interaction
32296183 GOA
enables sequence-specific double-stranded DNA binding IDA
IDA: Inferred from direct assay
28473536 GOA
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern

ZBTB12 Protein Structure

BTB

BTB: BTB/POZ domain (23 - 125)

zf-C2H2

zf-C2H2: Zinc finger, C2H2 type (359 - 381)

zf-C2H2

zf-C2H2: Zinc finger, C2H2 type (387 - 409)

zf-C2H2

zf-C2H2: Zinc finger, C2H2 type (415 - 438)

  • 0
  • 100
  • 200
  • 300
  • 400
  • 459 a.a.
Protein Preferred Names Protein Names

zinc finger and BTB domain-containing protein 12

  • HLA-B-associated transcript 9

ZBTB12 Protein-protein interaction Information

Type
Protein Name Protein ID Interactor Interactor Species Interactor ID Detection Method References
Intra
ZBTB12 Q9Y330 ZBTB26 Homo sapiens Q9HCK0
Y2H Array
32296183
Intra
ZBTB12 Q9Y330 ZBTB26 Homo sapiens Q9HCK0
Y2H Prey Pooling
32296183
Cross: Cross-species interaction Intra: Intraspecies interaction

Related Diseases

Diseases Alias
Immune System Organ Benign Neoplasm
Thymus Lipoma

  • Thymolipoma
Testicular Infarct

  • Infarction Of Testis

  • Testicular Infarction
Malignant Ovarian Cyst
Diseases Alias
Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (3)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-RS15962 ZBTB12 Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS21977 Zbtb12 Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS28494 Zbtb12 Rat Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Rattus norvegicus ZBTB12 RGD RGD:1302958
Mus musculus ZBTB12 MGD MGI:88133
Felis catus ZBTB12 VGNC VGNC:67161
Macaca mulatta ZBTB12 VGNC VGNC:79174
Bos taurus ZBTB12 VGNC VGNC:37060
Canis familiaris ZBTB12 VGNC VGNC:48522
Others ZBTB12 NCBI