BANP - BTG3 associated nuclear protein Gene

Also Known as BEND1; SMAR1; SMARBP1

Species: Homo sapiens

Gene Type: protein coding

Gene ID: 54971

About BANP

Cytogenetic location: 16q24.2 Genomic coordinates (GRCh38): 16:87,949,238-88,077,318 (from NCBI)

This gene has 29 transcripts (splice variants) and 209 orthologues. Ubiquitous expression in testis (RPKM 1.3), spleen (RPKM 1.1) and 25 other tissues.

Summary

This gene encodes a protein that binds to matrix attachment regions. The protein forms a complex with p53 and negatively regulates p53 transcription, and functions as a tumor suppressor and cell cycle regulator. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Mar 2010]

BANP Products (32)

mRNA	Protein	Name
NM_001173539.2	NP_001167010.1	protein BANP isoform c
NM_001173540.2	NP_001167011.1	protein BANP isoform d
NM_001173541.2	NP_001167012.1	protein BANP isoform e
NM_001173542.1	NP_001167013.1	protein BANP isoform f
NM_001173543.1	NP_001167014.1	protein BANP isoform g
NM_001384916.1	NP_001371845.1	protein BANP isoform a
NM_001384918.1	NP_001371847.1	protein BANP isoform c
NM_001384919.1	NP_001371848.1	protein BANP isoform c
NM_001384920.1	NP_001371849.1	protein BANP isoform c
NM_001384921.1	NP_001371850.1	protein BANP isoform e
NM_001384922.1	NP_001371851.1	protein BANP isoform e
NM_001384923.1	NP_001371852.1	protein BANP isoform e
NM_001384925.1	NP_001371854.1	protein BANP isoform f
NM_001384926.1	NP_001371855.1	protein BANP isoform f
NM_001384927.1	NP_001371856.1	protein BANP isoform f
NM_001384928.1	NP_001371857.1	protein BANP isoform h
NM_001384929.1	NP_001371858.1	protein BANP isoform h
NM_001384931.1	NP_001371860.1	protein BANP isoform i
NM_001384935.1	NP_001371864.1	protein BANP isoform i
NM_001384936.1	NP_001371865.1	protein BANP isoform j
NM_001384937.1	NP_001371866.1	protein BANP isoform j
NM_001384938.1	NP_001371867.1	protein BANP isoform k
NM_001384939.1	NP_001371868.1	protein BANP isoform l
NM_001384940.1	NP_001371869.1	protein BANP isoform l
NM_001384941.1	NP_001371870.1	protein BANP isoform m
NM_001384942.1	NP_001371871.1	protein BANP isoform m
NM_001384943.1	NP_001371872.1	protein BANP isoform n
NM_001384944.1	NP_001371873.1	protein BANP isoform o
NM_001386991.1	NP_001373920.1	protein BANP isoform p
NM_001386992.1	NP_001373921.1	protein BANP isoform q
NM_017869.4	NP_060339.2	protein BANP isoform a
NM_079837.3	NP_524576.2	protein BANP isoform b

Gene Ontology

Molecular Function

Molecular Function GO Annotation	Evidence	References	Source
enables identical protein binding	IPI IPI: Inferred from physical interaction	26871637	GOA
enables protein binding	IPI IPI: Inferred from physical interaction	16189514	GOA

EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern

BANP Protein Structure

BEN

0
100
200
300
400
519 a.a.

Protein Preferred Names	Protein Names
protein BANP	BEN domain-containing protein 1

BANP Protein-protein interaction Information

Type	Protein Name	Protein ID	Interactor	Interactor Species	Interactor ID	Detection Method	References
Intra	BANP	Q8N9N5	DCDC2B	Homo sapiens	A2VCK2	Y2H Prey Pooling	25416956
Intra	BANP	Q8N9N5	DCDC2B	Homo sapiens	A2VCK2	Y2H Array	25416956
Intra	BANP	Q8N9N5	SPACA6	Homo sapiens	W5XKT8	Y2H Prey Pooling	25416956
Intra	BANP	Q8N9N5	SPACA6	Homo sapiens	W5XKT8	Validated Y2H	25416956
Intra	BANP	Q8N9N5	ZMIZ2	Homo sapiens	Q8NF64-2	Validated Y2H	25416956
Intra	BANP	Q8N9N5	SH3RF2	Homo sapiens	Q08AM8	Y2H Array	25416956
Intra	BANP	Q8N9N5	SH3RF2	Homo sapiens	Q08AM8	Validated Y2H	25416956
Intra	BANP	Q8N9N5	MGC4677	Homo sapiens	Q53S70	Y2H Prey Pooling	25416956
Intra	BANP	Q8N9N5	EPHA10	Homo sapiens	Q5JZY3-3	Y2H Array	25416956
Intra	BANP	Q8N9N5	EPHA10	Homo sapiens	Q5JZY3-3	Y2H Prey Pooling	25416956
Intra	BANP	Q8N9N5	FOXR1	Homo sapiens	Q6PIV2	Validated Y2H	25416956
Intra	BANP	Q8N9N5	FOXR1	Homo sapiens	Q6PIV2	Y2H Array	25416956
Intra	BANP	Q8N9N5	PID1	Homo sapiens	Q7Z2X4	Y2H Array	25416956
Intra	BANP	Q8N9N5	PID1	Homo sapiens	Q7Z2X4	Validated Y2H	25416956
Intra	BANP	Q8N9N5	LGALS14	Homo sapiens	Q8TCE9	Validated Y2H	25416956
Intra	BANP	Q8N9N5	DNAJA4	Homo sapiens	Q8WW22-2	Y2H Array	25416956
Intra	BANP	Q8N9N5	DNAJA4	Homo sapiens	Q8WW22-2	Validated Y2H	25416956
Intra	BANP	Q8N9N5	PRKCH	Homo sapiens	Q9BVQ0	Y2H Array	25416956
Intra	BANP	Q8N9N5	PRKCH	Homo sapiens	Q9BVQ0	Validated Y2H	25416956
Intra	BANP	Q8N9N5	ISCU	Homo sapiens	Q9H1K1	Y2H Array	25416956
Intra	BANP	Q8N9N5	PRKAB2	Homo sapiens	O43741	Validated Y2H	25416956
Intra	BANP	Q8N9N5	PRKAB2	Homo sapiens	O43741	Y2H Prey Pooling	25416956
Intra	BANP	Q8N9N5	POGZ	Homo sapiens	Q7Z3K3	Y2H Prey Pooling	25416956
Intra	BANP	Q8N9N5	POGZ	Homo sapiens	Q7Z3K3	Validated Y2H	25416956
Intra	BANP	Q8N9N5	NEDD9	Homo sapiens	Q14511	Validated Y2H	25416956
Intra	BANP	Q8N9N5	NEDD9	Homo sapiens	Q14511	Y2H	21516116
Intra	BANP	Q8N9N5	NEDD9	Homo sapiens	Q14511	Y2H Array	25416956
Intra	BANP	Q8N9N5	NEDD9	Homo sapiens	Q14511	Y2H Prey Pooling	25416956
Intra	BANP	Q8N9N5	ALAS2	Homo sapiens	P22557	Validated Y2H	25416956
Intra	BANP	Q8N9N5	ALAS2	Homo sapiens	P22557	Y2H Array	25416956
Intra	BANP	Q8N9N5	SH3RF2	Homo sapiens	Q8TEC5	Validated Y2H	25416956
Intra	BANP	Q8N9N5	SH3RF2	Homo sapiens	Q8TEC5	Y2H Prey Pooling	25416956
Intra	BANP	Q8N9N5	SH3RF2	Homo sapiens	Q8TEC5	Y2H Array	25416956
Intra	BANP	Q8N9N5	XAGE1A	Homo sapiens	Q9HD64	Validated Y2H	25416956
Intra	BANP	Q8N9N5	TROAP	Homo sapiens	Q12815	Validated Y2H	25416956
Intra	BANP	Q8N9N5	TROAP	Homo sapiens	Q12815	Y2H Prey Pooling	25416956
Intra	BANP	Q8N9N5	GFM2	Homo sapiens	Q969S9	Y2H Prey Pooling	25416956
Intra	BANP	Q8N9N5	GFM2	Homo sapiens	Q969S9	Validated Y2H	25416956
Intra	BANP	Q8N9N5	GFM2	Homo sapiens	Q969S9	Y2H Array	25416956
Intra	BANP	Q8N9N5	COL10A1	Homo sapiens	Q03692	Y2H Prey Pooling	25416956
Intra	BANP	Q8N9N5	COL10A1	Homo sapiens	Q03692	Validated Y2H	25416956
Intra	BANP	Q8N9N5	COL10A1	Homo sapiens	Q03692	Y2H Array	25416956
Intra	BANP	Q8N9N5	L3MBTL3	Homo sapiens	Q96JM7	Validated Y2H	25416956
Intra	BANP	Q8N9N5	LMO4	Homo sapiens	P61968	Y2H Prey Pooling	25416956
Intra	BANP	Q8N9N5	TNXB	Homo sapiens	P22105	Validated Y2H	25416956
Intra	BANP	Q8N9N5	TNXB	Homo sapiens	P22105	Y2H Array	25416956
Intra	BANP	Q8N9N5	TNXB	Homo sapiens	P22105	Y2H Prey Pooling	25416956
Intra	BANP	Q8N9N5	TNXB	Homo sapiens	P22105	Y2H	21516116
Intra	BANP	Q8N9N5	AFG1L	Homo sapiens	Q8WV93	Y2H Array	25416956
Intra	BANP	Q8N9N5	AFG1L	Homo sapiens	Q8WV93	Y2H Prey Pooling	25416956
Intra	BANP	Q8N9N5	LSM2	Homo sapiens	Q9Y333	Y2H Prey Pooling	25416956
Intra	BANP	Q8N9N5	LSM2	Homo sapiens	Q9Y333	Validated Y2H	25416956
Intra	BANP	Q8N9N5	LSM2	Homo sapiens	Q9Y333	Y2H Array	25416956
Intra	BANP	Q8N9N5	CAMK2D	Homo sapiens	Q13557	Y2H Array	31515488
Intra	BANP	Q8N9N5	CAMK2D	Homo sapiens	Q13557	Validated Y2H	25416956
Intra	BANP	Q8N9N5	TRAF2	Homo sapiens	Q12933	Y2H Array	25416956
Intra	BANP	Q8N9N5	TRAF2	Homo sapiens	Q12933	Validated Y2H	25416956
Intra	BANP	Q8N9N5	BAG5	Homo sapiens	Q9UL15	Y2H Prey Pooling	25416956
Intra	BANP	Q8N9N5	BAG5	Homo sapiens	Q9UL15	Validated Y2H	25416956
Intra	BANP	Q8N9N5	PPIB	Homo sapiens	P23284	Y2H Prey Pooling	25416956
Intra	BANP	Q8N9N5	POLR2L	Homo sapiens	P62875	Y2H Array	25416956
Intra	BANP	Q8N9N5	TRAF4	Homo sapiens	Q9BUZ4	Validated Y2H	25416956
Intra	BANP	Q8N9N5	TRAF4	Homo sapiens	Q9BUZ4	Y2H Array	25416956
Intra	BANP	Q8N9N5	TP53	Homo sapiens	P04637	Anti Bait CoIP	20075864
Intra	BANP	Q8N9N5	SNRPB	Homo sapiens	P14678-2	Y2H Array	25416956
Intra	BANP	Q8N9N5	SNRPB	Homo sapiens	P14678-2	Y2H Prey Pooling	25416956
Intra	BANP	Q8N9N5	SNRPB	Homo sapiens	P14678-2	Validated Y2H	25416956
Intra	BANP	Q8N9N5	FAM117B	Homo sapiens	Q6P1L5	Y2H Prey Pooling	25416956
Intra	BANP	Q8N9N5	FAM117B	Homo sapiens	Q6P1L5	Y2H Array	25416956
Intra	BANP	Q8N9N5	NRIP2	Homo sapiens	Q9BQI9	Y2H Array	25416956
Intra	BANP	Q8N9N5	NRIP2	Homo sapiens	Q9BQI9	Y2H Prey Pooling	25416956
Intra	BANP	Q8N9N5	MAP2K1	Homo sapiens	Q02750	Y2H Array	25416956
Intra	BANP	Q8N9N5	RBM39	Homo sapiens	Q14498-3	Y2H Array	25416956
Intra	BANP	Q8N9N5	FAM90A1	Homo sapiens	Q86YD7	Y2H Array	25416956
Intra	BANP	Q8N9N5	FAM90A1	Homo sapiens	Q86YD7	Y2H Prey Pooling	25416956
Intra	BANP	Q8N9N5	FAM90A1	Homo sapiens	Q86YD7	Validated Y2H	25416956
Intra	BANP	Q8N9N5	PIM1	Homo sapiens	P11309	Y2H Prey Pooling	25416956
Intra	BANP	Q8N9N5	PIM1	Homo sapiens	P11309	Validated Y2H	25416956
Intra	BANP	Q8N9N5	PIM1	Homo sapiens	P11309	Y2H Array	25416956
Intra	BANP	Q8N9N5	FHL2	Homo sapiens	Q14192	Validated Y2H	25416956
Intra	BANP	Q8N9N5	FHL2	Homo sapiens	Q14192	Y2H Array	25416956
Intra	BANP	Q8N9N5	FHL2	Homo sapiens	Q14192	Y2H Array	31515488
Intra	BANP	Q8N9N5	MRPL28	Homo sapiens	Q13084	Y2H Prey Pooling	25416956
Intra	BANP	Q8N9N5	LENG1	Homo sapiens	Q96BZ8	Y2H Prey Pooling	25416956
Intra	BANP	Q8N9N5	C22orf39	Homo sapiens	Q6P5X5	Y2H Array	25416956
Intra	BANP	Q8N9N5	LMO2	Homo sapiens	P25791	Y2H Prey Pooling	25416956
Intra	BANP	Q8N9N5	LMO2	Homo sapiens	P25791	Y2H Array	25416956
Intra	BANP	Q8N9N5	RBPMS	Homo sapiens	Q93062	Y2H Array	25416956
Intra	BANP	Q8N9N5	ZC2HC1C	Homo sapiens	Q53FD0	Y2H Prey Pooling	25416956
Intra	BANP	Q8N9N5	LMO3	Homo sapiens	Q8TAP4	Y2H Prey Pooling	25416956
Intra	BANP	Q8N9N5	CEP76	Homo sapiens	Q8TAP6	Y2H Prey Pooling	25416956
Intra	BANP	Q8N9N5	PHF21A	Homo sapiens	Q96BD5	Y2H Array	25416956
Intra	BANP	Q8N9N5	PHF21A	Homo sapiens	Q96BD5	Y2H Array	31515488
Intra	BANP	Q8N9N5	PHF21A	Homo sapiens	Q96BD5	Validated Y2H	25416956
Intra	BANP	Q8N9N5	ZNF581	Homo sapiens	Q9P0T4	Y2H Array	25416956
Intra	BANP	Q8N9N5	ZNF581	Homo sapiens	Q9P0T4	Y2H Prey Pooling	25416956
Intra	BANP	Q8N9N5	RAB3IP	Homo sapiens	Q96QF0	Y2H Array	25416956
Intra	BANP	Q8N9N5	CFAP206	Homo sapiens	Q8IYR0	Y2H Array	25416956
Intra	BANP	Q8N9N5	CFAP206	Homo sapiens	Q8IYR0	Validated Y2H	25416956
Intra	BANP	Q8N9N5	PSMD9	Homo sapiens	O00233	Validated Y2H	25416956
Intra	BANP	Q8N9N5	MAX	Homo sapiens	P61244	Y2H Prey Pooling	25416956
Intra	BANP	Q8N9N5	MAX	Homo sapiens	P61244	Validated Y2H	25416956
Intra	BANP	Q8N9N5	MAX	Homo sapiens	P61244	Y2H Array	25416956
Intra	BANP	Q8N9N5	GARIN6	Homo sapiens	Q8NEG0	Validated Y2H	25416956
Intra	BANP	Q8N9N5	GARIN6	Homo sapiens	Q8NEG0	Y2H Array	25416956
Intra	BANP	Q8N9N5	SLC16A3	Homo sapiens	O15427	Y2H Array	25416956
Intra	BANP	Q8N9N5	ADAM15	Homo sapiens	Q13444	Y2H Prey Pooling	25416956
Intra	BANP	Q8N9N5	ADAM15	Homo sapiens	Q13444	Y2H Array	25416956
Intra	BANP	Q8N9N5	SP2	Homo sapiens	Q02086	Y2H Prey Pooling	25416956
Intra	BANP	Q8N9N5	SP2	Homo sapiens	Q02086	Y2H Array	25416956
Intra	BANP	Q8N9N5	C1orf94	Homo sapiens	Q6P1W5	Y2H Prey Pooling	25416956
Intra	BANP	Q8N9N5	C1orf94	Homo sapiens	Q6P1W5	Y2H Array	25416956
Intra	BANP	Q8N9N5	ZNF488	Homo sapiens	Q96MN9	Y2H Prey Pooling	25416956
Intra	BANP	Q8N9N5	TOX4	Homo sapiens	O94842	Validated Y2H	25416956
Intra	BANP	Q8N9N5	TOX4	Homo sapiens	O94842	Y2H Prey Pooling	25416956
Intra	BANP	Q8N9N5	PPIC	Homo sapiens	P45877	Y2H Prey Pooling	25416956
Intra	BANP	Q8N9N5	PPIC	Homo sapiens	P45877	Validated Y2H	25416956
Intra	BANP	Q8N9N5	PPIC	Homo sapiens	P45877	Y2H Array	25416956

Cross: Cross-species interaction Intra: Intraspecies interaction

BANP Antibodies

Cat. No.	Product Name	Application	Reactivity
HY-P810828	BANP Antibody (YA10071)	WB, IHC-P	Human

Related Diseases

Diseases	Alias
Keratoconus	Kc Conical Cornea Noninflammatory Corneal Thining Bulging Cornea Cornea Conical Acquired Conus Of Cornea
Breast Cancer	Breast Carcinoma Male Breast Cancer Breast Cancer, Familial Malignant Neoplasm Of Breast Breast Cancer, Susceptibility To Breast Cancer, Early-Onset Malignant Tumor Of Breast Carcinoma Of Male Breast Breast Cancer, Invasive Ductal Breast Cancer, Protection Against Breast Cancer, Somatic Breast Cancer, Male Breast Cancer, Lobular, Somatic Breast Tumor Mammary Cancer Mammary Tumor Malignant Neoplasm Of Male Breast Mammary Carcinoma Male Breast Carcinoma Familial Cancer Of Breast Invasive Ductal Breast Carcinoma Breast Cancer Susceptibility Breast Cancer, Male, Susceptibility To Breast Cancer, Early-Onset, Susceptibility To Malignant Tumor Of The Breast Mammary Neoplasm Primary Breast Cancer Neoplasm Of Male Breast Carcinoma Of Breast Breast Cancer In Men Familial Breast Cancer Cancer Of Breast BC Breast Cancer Familial Breast Cancer Familial Male Breast Cancer, Familial Male Breast Male Carcinoma Breast Neoplasms Breast Neoplasms, Male Mammary Tumors Mammary Carcinomas Cancer, Breast Cancer, Breast, Susceptibility Invasive Breast Ductal Carcinoma Breast Neoplasm Susceptibility To Breast Cancer Mammary Neoplasms Animal Mammary Neoplasms Primary Malignant Neoplasm Of Breast Infiltrating Ductal Carcinoma Of Breast Infiltrating Duct Carcinoma Of Unspecified Site Infiltrating Ductular Carcinoma Of Unspecified Site Invasive Breast Carcinoma Of No Special Type Microinvasive Carcinoma Of Breast Carcinoma With Apocrine Differentiation

Diseases	Alias
Waldenstroem'S Macroglobulinemia	Waldenstroem'S Macroglobulinemia Waldenstroem'S Macroglobulinemia Macroglobulinemia Of Waldenstrom Lymphoplasmacytic Lymphoma With Igm Gammopathy Lymphoplasmacytic Lymphoma Waldenstroem'S Macroglobulinemia Waldenstroem'S Macroglobulinemia Macroglobulinemia Of Waldenstrom Lymphoplasmacytic Lymphoma With Igm Gammopathy Lymphoplasmacytic Lymphoma

Related Agents

Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (1)

Cat. No.	Product Name	Effect	Purity	Rare Diseases
HY-RS01363	BANP Human Pre-designed siRNA Set A	Pre-designed Set	/	Unkown

Orthologs Information

Species	Symbol	Source	ID
Rattus norvegicus	BANP	RGD	RGD:1307464
Canis familiaris	BANP	VGNC	VGNC:38378
Macaca mulatta	BANP	VGNC	VGNC:70057
Bos taurus	BANP	VGNC	VGNC:26418
Mus musculus	BANP	MGD	MGI:1889023
Felis catus	BANP	VGNC	VGNC:60073
Others	BANP	NCBI