CEP76 - centrosomal protein 76 Gene

Homo sapiens

Also known as C18orf9; HsT1705

Gene ID: 79959 | Gene type: protein coding

About CEP76

This gene has 12 transcripts (splice variants), 207 orthologues and 2 paralogues. Broad expression in testis (RPKM 7.3), esophagus (RPKM 1.7) and 23 other tissues.

Summary

This gene encodes a centrosomal protein which regulates centriole amplification by limiting centriole duplication to once per cell cycle. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Dec 2012]

CEP76 Products(2)

mRNA	Protein	Name
NM_001271989.2	NP_001258918.1	centrosomal protein of 76 kDa isoform b
NM_024899.4	NP_079175.2	centrosomal protein of 76 kDa isoform a

CEP76 Protein Structure

CEP76-C2

0
200
400
600
659 a.a.

Protein Preferred Names

Protein Names

centrosomal protein of 76 kDa

centrosomal protein 76kDa

Related Diseases

Diseases

Alias

Jawad Syndrome

JWDS	Kelly Syndrome
Microcephaly With Mental Retardation And Digital Anomalies	Kelly
Microcephaly-Digital Anomalies Syndrome	Plummer-Vinson Syndrome

Neu-Laxova Syndrome 2

NLS2

Nail Disorder, Nonsyndromic Congenital, 4

Anonychia Congenita	Anonychia
Hyponychia Congenita	NDNC4
Anonychia/Hyponychia Congenita	Nonsyndromic Congenital Nail Disorder 4
Isolated Congenital Anonychia	Anonychia Congenita Totalis
Anonychia Totalis	Autosomal Recessive Nonsyndromic Congenital Nail Disorder-4
Congenital Anonychia	Nonsyndromic Congenital Nail Disorder, 4
Absent Nails	Aplastic Nails
Congenital Absence Of Nails	Isolated Anonychia
Nail Disorder, Non-Syndromic Congenital, 4	Nail Disorder, Nonsyndromic, Congenital, Type 4

Nonsyndromic Congenital Nail Disorder

Nail Disorder, Nonsyndromic Congenital

Nephronophthisis 14

Joubert Syndrome 19	NPHP14
JBTS19	Nephronophthisis, Type 14

Microcephaly

Microencephaly	Microcephalus
Microcephalic	Nanocephaly
Congenital Microcephaly	Brain Hypoplasia
Brain Nondevelopment	Cephalic Hypoplasia
Undeveloped Cerebrum	Undeveloped Brain
Micrencephalon	Micrencephaly

Diseases	Alias
Waldenstroem'S Macroglobulinemia	Waldenstroem'S Macroglobulinemia Waldenstroem'S Macroglobulinemia Macroglobulinemia Of Waldenstrom Lymphoplasmacytic Lymphoma With Igm Gammopathy Lymphoplasmacytic Lymphoma Waldenstroem'S Macroglobulinemia Waldenstroem'S Macroglobulinemia Macroglobulinemia Of Waldenstrom Lymphoplasmacytic Lymphoma With Igm Gammopathy Lymphoplasmacytic Lymphoma

Related Agents

Pre-clinical Phase

Bioactive Molecules (1)

Cat. No.	Product Name	Effect	Purity	Rare Diseases
HY-RS02523	CEP76 Human Pre-designed siRNA Set A		/	Unkown

Orthologs Information

Species	Symbol	Source	ID
Bos taurus	CEP76	VGNC	VGNC:27213
Rattus norvegicus	CEP76	RGD	RGD:1305183
Canis familiaris	CEP76	VGNC	VGNC:39137
Felis catus	CEP76	VGNC	VGNC:60783
Macaca mulatta	CEP76	VGNC	VGNC:104217
Mus musculus	CEP76	MGD	MGI:1923401

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