CCDC92 - coiled-coil domain containing 92 Gene

Species: Homo sapiens

Gene Type: protein coding
Gene ID: 80212

About CCDC92

This gene has 9 transcripts (splice variants), 1 gene allele, 205 orthologues and 1 paralogue. Broad expression in brain (RPKM 20.8), testis (RPKM 19.4) and 25 other tissues.

Summary

Enables identical protein binding activity. Located in centriole; centrosome; and nucleoplasm. [provided by Alliance of Genome Resources, Apr 2022]

CCDC92 Products (6)

mRNA Protein Name
NM_001304957.2 NP_001291886.1 coiled-coil domain-containing protein 92 isoform 1
NM_001304958.2 NP_001291887.1 coiled-coil domain-containing protein 92 isoform 1
NM_001304959.2 NP_001291888.1 coiled-coil domain-containing protein 92 isoform 1
NM_001304960.2 NP_001291889.1 coiled-coil domain-containing protein 92 isoform 1
NM_001304961.2 NP_001291890.1 coiled-coil domain-containing protein 92 isoform 2
NM_025140.3 NP_079416.1 coiled-coil domain-containing protein 92 isoform 1

Gene Ontology

  • Molecular Function
  • Cellular Component
Molecular Function GO Annotation Evidence References Source
enables identical protein binding IPI
IPI: Inferred from physical interaction
32296183 GOA
enables protein binding IPI
IPI: Inferred from physical interaction
22458338 GOA
Cellular Component GO Annotation Evidence References Source
located in centriole IDA
IDA: Inferred from direct assay
22863007 GOA
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern

CCDC92 Protein Structure

CCDC92

CCDC92: Coiled-coil domain of unknown function (23 - 82)

  • 0
  • 100
  • 200
  • 300
  • 331 a.a.
Protein Preferred Names Protein Names

coiled-coil domain-containing protein 92

  • limkain beta 2

CCDC92 Protein-protein interaction Information

Type
Protein Name Protein ID Interactor Interactor Species Interactor ID Detection Method References
Intra
CCDC92 Q53HC0 TP53BP2 Homo sapiens Q13625-3
Y2H Prey Pooling
25416956
Intra
CCDC92 Q53HC0 TRIML2 Homo sapiens Q8N7C3
Validated Y2H
32296183
Intra
CCDC92 Q53HC0 DISC1 Homo sapiens Q9NRI5-2
Y2H Prey Pooling
32296183
Intra
CCDC92 Q53HC0 DISC1 Homo sapiens Q9NRI5-2
Validated Y2H
32296183
Intra
CCDC92 Q53HC0 DISC1 Homo sapiens Q9NRI5-2
Y2H Array
32296183
Intra
CCDC92 Q53HC0 CEP164 Homo sapiens Q9UPV0
Confocal
22863007
Intra
CCDC92 Q53HC0 CEP164 Homo sapiens Q9UPV0
Anti Tag CoIP
22863007
Intra
CCDC92 Q53HC0 CEP164 Homo sapiens Q9UPV0
Pull Down
22863007
Intra
CCDC92 Q53HC0 FHL2 Homo sapiens Q14192
Y2H Array
25416956
Intra
CCDC92 Q53HC0 FHL2 Homo sapiens Q14192
Y2H Array
31515488
Intra
CCDC92 Q53HC0 TRIM27 Homo sapiens P14373
Validated Y2H
25416956
Intra
CCDC92 Q53HC0 TRIM27 Homo sapiens P14373
Y2H Array
25416956
Intra
CCDC92 Q53HC0 CCDC92 Homo sapiens Q53HC0
Validated Y2H
32296183
Intra
CCDC92 Q53HC0 CCDC92 Homo sapiens Q53HC0
Y2H Array
32296183
Intra
CCDC92 Q53HC0 CCDC92 Homo sapiens Q53HC0
Y2H Prey Pooling
32296183
Intra
CCDC92 Q53HC0 CEP76 Homo sapiens Q8TAP6
Y2H Prey Pooling
25416956
Intra
CCDC92 Q53HC0 CEP76 Homo sapiens Q8TAP6
Validated Y2H
25416956
Cross
CCDC92 Q53HC0 tax Human T-cell leukemia virus 1 P14079
MAPPIT
22458338
Cross: Cross-species interaction Intra: Intraspecies interaction

Related Diseases

Diseases Alias
Lipodystrophy, Familial Partial, Type 1

  • FPLD1

  • Familial Partial Lipodystrophy Type 1

  • Familial Partial Lipodystrophy, Kobberling Type

  • Lipodystrophy, Familial Partial, Kobberling Type

  • Familial Partial Lipodystrophy Kobberling Type

  • Familial Partial Lipodystrophy Type Köbberling

  • Familial Partial Lipodystrophy, Köbberling Type

  • Familial Partial Lipodystrophy, Type 1
Diseases Alias
Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (1)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-RS02067 CCDC92 Human Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Rattus norvegicus CCDC92 RGD RGD:1601131
Macaca mulatta CCDC92 VGNC VGNC:70906
Felis catus CCDC92 VGNC VGNC:60529
Bos taurus CCDC92 VGNC VGNC:26933
Mus musculus CCDC92 MGD MGI:106485
Canis familiaris CCDC92 VGNC VGNC:38873
Others CCDC92 NCBI