TRIML2 - tripartite motif family like 2 Gene
Also Known as SPRYD6
Species: Homo sapiens
Gene Type: protein coding
Gene ID: 205860
Summary
This gene encodes a member of the tri-partite motif (TRIM) family of proteins. This protein may be regulated by the tumor suppressor p53 and may regulate p53 through the enhancement of p53 SUMOylation. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Dec 2014]
Biased expression in placenta (RPKM 2.0) and testis (RPKM 1.2).
TRIML2 Products (2)
| mRNA | Protein | Name |
|---|---|---|
| NM_001303419.1 | NP_001290348.1 | probable E3 ubiquitin-protein ligase TRIML2 isoform 1 |
| NM_173553.4 | NP_775824.2 | probable E3 ubiquitin-protein ligase TRIML2 isoform 2 |
| Molecular Function GO Annotation | Evidence | Références | Source |
|---|---|---|---|
| enables identical protein binding |
IPI
IPI: Inferred from physical interaction
|
32296183 | GOA |
| enables protein binding |
IPI
IPI: Inferred from physical interaction
|
26496610 | GOA |
EXP: Inferred from Experiment
IDA: Inferred from direct assay
IPI: Inferred from physical interaction
IMP: Inferred from mutant phenotype
IGI: Inferred from genetic interaction
IEP: Inferred from expression pattern
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TRIML2 Protein-protein interaction Information
|
Type
|
Protein Name | Protein ID | Interactor | Interactor Species | Interactor ID | Detection Method | Références |
|---|---|---|---|---|---|---|---|
|
Intra
|
TRIML2 | Q8N7C3 | CTBP2 | Homo sapiens | P56545-3 | 32296183 | |
|
Intra
|
TRIML2 | Q8N7C3 | CTBP2 | Homo sapiens | P56545-3 | 32296183 | |
|
Intra
|
TRIML2 | Q8N7C3 | NECAB2 | Homo sapiens | Q7Z6G3-2 | 32296183 | |
|
Intra
|
TRIML2 | Q8N7C3 | NECAB2 | Homo sapiens | Q7Z6G3-2 | 32296183 | |
|
Intra
|
TRIML2 | Q8N7C3 | CCHCR1 | Homo sapiens | Q8TD31-3 | 32296183 | |
|
Intra
|
TRIML2 | Q8N7C3 | NFKBID | Homo sapiens | Q8NI38 | 32296183 | |
|
Intra
|
TRIML2 | Q8N7C3 | KRT34 | Homo sapiens | O76011 | 32296183 | |
|
Intra
|
TRIML2 | Q8N7C3 | KRT34 | Homo sapiens | O76011 | 32296183 | |
|
Intra
|
TRIML2 | Q8N7C3 | KRT38 | Homo sapiens | O76015 | 32296183 | |
|
Intra
|
TRIML2 | Q8N7C3 | KRT38 | Homo sapiens | O76015 | 32296183 | |
|
Intra
|
TRIML2 | Q8N7C3 | TFIP11 | Homo sapiens | Q9UBB9 | 32296183 | |
|
Intra
|
TRIML2 | Q8N7C3 | TFIP11 | Homo sapiens | Q9UBB9 | 32296183 | |
|
Intra
|
TRIML2 | Q8N7C3 | TFIP11 | Homo sapiens | Q9UBB9 | 32296183 | |
|
Intra
|
TRIML2 | Q8N7C3 | ZBTB33 | Homo sapiens | Q86T24 | 32296183 | |
|
Intra
|
TRIML2 | Q8N7C3 | ZBTB33 | Homo sapiens | Q86T24 | 33961781 | |
|
Intra
|
TRIML2 | Q8N7C3 | CCDC92 | Homo sapiens | Q53HC0 | 32296183 | |
|
Intra
|
TRIML2 | Q8N7C3 | CCDC92 | Homo sapiens | Q53HC0 | 33961781 | |
|
Intra
|
TRIML2 | Q8N7C3 | ZBTB33 | Homo sapiens | Q86T24 | 28514442 | |
|
Intra
|
TRIML2 | Q8N7C3 | CCDC92 | Homo sapiens | Q53HC0 | 28514442 | |
|
Intra
|
TRIML2 | Q8N7C3 | BLOC1S2 | Homo sapiens | Q6QNY1 | 33961781 | |
|
Intra
|
TRIML2 | Q8N7C3 | BLOC1S2 | Homo sapiens | Q6QNY1 | 32296183 | |
|
Intra
|
TRIML2 | Q8N7C3 | ZBTB33 | Homo sapiens | Q86T24 | 32296183 | |
|
Intra
|
TRIML2 | Q8N7C3 | CCDC92 | Homo sapiens | Q53HC0 | 32296183 | |
|
Intra
|
TRIML2 | Q8N7C3 | BLOC1S2 | Homo sapiens | Q6QNY1 | 28514442 | |
|
Intra
|
TRIML2 | Q8N7C3 | BLOC1S2 | Homo sapiens | Q6QNY1 | 32296183 | |
|
Intra
|
TRIML2 | Q8N7C3 | ABI2 | Homo sapiens | Q9NYB9-2 | 32296183 | |
|
Intra
|
TRIML2 | Q8N7C3 | CBY2 | Homo sapiens | Q8NA61-2 | 32296183 | |
|
Intra
|
TRIML2 | Q8N7C3 | CDR2 | Homo sapiens | Q01850 | 32296183 | |
|
Intra
|
TRIML2 | Q8N7C3 | TBC1D25 | Homo sapiens | Q3MII6 | 32296183 | |
|
Intra
|
TRIML2 | Q8N7C3 | TBC1D25 | Homo sapiens | Q3MII6 | 32296183 | |
|
Intra
|
TRIML2 | Q8N7C3 | MBD3L2 | Homo sapiens | Q8NHZ7 | 32296183 | |
|
Intra
|
TRIML2 | Q8N7C3 | POU6F2 | Homo sapiens | P78424 | 32296183 | |
|
Intra
|
TRIML2 | Q8N7C3 | POU6F2 | Homo sapiens | P78424 | 32296183 | |
|
Intra
|
TRIML2 | Q8N7C3 | TCF4 | Homo sapiens | P15884-3 | 32296183 | |
|
Intra
|
TRIML2 | Q8N7C3 | TCF4 | Homo sapiens | P15884-3 | 32296183 | |
|
Intra
|
TRIML2 | Q8N7C3 | MEOX2 | Homo sapiens | Q6FHY5 | 32296183 | |
|
Intra
|
TRIML2 | Q8N7C3 | MEOX2 | Homo sapiens | Q6FHY5 | 32296183 | |
|
Intra
|
TRIML2 | Q8N7C3 | TRIM54 | Homo sapiens | Q9BYV2 | 32296183 | |
|
Intra
|
TRIML2 | Q8N7C3 | TRIM54 | Homo sapiens | Q9BYV2 | 32296183 | |
|
Intra
|
TRIML2 | Q8N7C3 | TRIM54 | Homo sapiens | Q9BYV2 | 32296183 | |
|
Intra
|
TRIML2 | Q8N7C3 | XAF1 | Homo sapiens | Q6GPH4 | 32296183 | |
|
Intra
|
TRIML2 | Q8N7C3 | XAF1 | Homo sapiens | Q6GPH4 | 32296183 | |
|
Intra
|
TRIML2 | Q8N7C3 | MEOX1 | Homo sapiens | P50221 | 32296183 | |
|
Intra
|
TRIML2 | Q8N7C3 | MEOX1 | Homo sapiens | P50221 | 32296183 | |
|
Intra
|
TRIML2 | Q8N7C3 | FAM9C | Homo sapiens | Q8IZT9 | 32296183 | |
|
Intra
|
TRIML2 | Q8N7C3 | FAM9C | Homo sapiens | Q8IZT9 | 32296183 | |
|
Intra
|
TRIML2 | Q8N7C3 | KRT75 | Homo sapiens | O95678 | 32296183 | |
|
Intra
|
TRIML2 | Q8N7C3 | KRT75 | Homo sapiens | O95678 | 32296183 | |
|
Intra
|
TRIML2 | Q8N7C3 | KRT24 | Homo sapiens | Q2M2I5 | 32296183 | |
|
Intra
|
TRIML2 | Q8N7C3 | KRT24 | Homo sapiens | Q2M2I5 | 32296183 | |
|
Intra
|
TRIML2 | Q8N7C3 | KRT27 | Homo sapiens | Q7Z3Y8 | 32296183 | |
|
Intra
|
TRIML2 | Q8N7C3 | KRT27 | Homo sapiens | Q7Z3Y8 | 32296183 | |
|
Intra
|
TRIML2 | Q8N7C3 | TSG101 | Homo sapiens | Q99816 | 32296183 | |
|
Intra
|
TRIML2 | Q8N7C3 | NUP62 | Homo sapiens | P37198 | 32296183 | |
|
Intra
|
TRIML2 | Q8N7C3 | NUP62 | Homo sapiens | P37198 | 32296183 | |
|
Intra
|
TRIML2 | Q8N7C3 | EIF3M | Homo sapiens | Q7L2H7 | 32296183 | |
|
Intra
|
TRIML2 | Q8N7C3 | EIF3M | Homo sapiens | Q7L2H7 | 32296183 | |
|
Intra
|
TRIML2 | Q8N7C3 | POLR1H | Homo sapiens | Q9P1U0 | 32296183 | |
|
Intra
|
TRIML2 | Q8N7C3 | POLR1H | Homo sapiens | Q9P1U0 | 32296183 | |
|
Intra
|
TRIML2 | Q8N7C3 | POLR1H | Homo sapiens | Q9P1U0 | 32296183 | |
|
Intra
|
TRIML2 | Q8N7C3 | ING5 | Homo sapiens | Q8WYH8 | 32296183 | |
|
Intra
|
TRIML2 | Q8N7C3 | ING5 | Homo sapiens | Q8WYH8 | 32296183 | |
|
Intra
|
TRIML2 | Q8N7C3 | ING5 | Homo sapiens | Q8WYH8 | 32296183 | |
|
Intra
|
TRIML2 | Q8N7C3 | EIF2B1 | Homo sapiens | Q14232 | 32296183 | |
|
Intra
|
TRIML2 | Q8N7C3 | EIF2B1 | Homo sapiens | Q14232 | 32296183 | |
|
Intra
|
TRIML2 | Q8N7C3 | ITGB3BP | Homo sapiens | Q13352 | 32296183 | |
|
Intra
|
TRIML2 | Q8N7C3 | ITGB3BP | Homo sapiens | Q13352 | 32296183 | |
|
Intra
|
TRIML2 | Q8N7C3 | KRT15 | Homo sapiens | P19012 | 32296183 | |
|
Intra
|
TRIML2 | Q8N7C3 | KRT15 | Homo sapiens | P19012 | 32296183 | |
|
Intra
|
TRIML2 | Q8N7C3 | USHBP1 | Homo sapiens | Q8N6Y0 | 32296183 | |
|
Intra
|
TRIML2 | Q8N7C3 | ZBED1 | Homo sapiens | O96006 | 32296183 | |
|
Intra
|
TRIML2 | Q8N7C3 | ZBED1 | Homo sapiens | O96006 | 32296183 | |
|
Intra
|
TRIML2 | Q8N7C3 | HGS | Homo sapiens | O14964 | 32296183 | |
|
Intra
|
TRIML2 | Q8N7C3 | HGS | Homo sapiens | O14964 | 32296183 | |
|
Intra
|
TRIML2 | Q8N7C3 | CCNH | Homo sapiens | P51946 | 32296183 | |
|
Intra
|
TRIML2 | Q8N7C3 | CCNH | Homo sapiens | P51946 | 32296183 | |
|
Intra
|
TRIML2 | Q8N7C3 | STN1 | Homo sapiens | Q9H668 | 32296183 | |
|
Intra
|
TRIML2 | Q8N7C3 | STN1 | Homo sapiens | Q9H668 | 32296183 | |
|
Intra
|
TRIML2 | Q8N7C3 | STN1 | Homo sapiens | Q9H668 | 32296183 | |
|
Intra
|
TRIML2 | Q8N7C3 | SH2D4A | Homo sapiens | Q9H788 | 32296183 | |
|
Intra
|
TRIML2 | Q8N7C3 | PICK1 | Homo sapiens | Q9NRD5 | 32296183 | |
|
Intra
|
TRIML2 | Q8N7C3 | KRT31 | Homo sapiens | Q15323 | 32296183 | |
|
Intra
|
TRIML2 | Q8N7C3 | KRT31 | Homo sapiens | Q15323 | 32296183 |
Cross: Cross-species interaction
Intra: Intraspecies interaction