2. Recombinant Proteins
  3. Enzymes & Regulators
  4. Serine/Threonine Kinase Proteins
  5. Cyclin-Dependent Kinases (CDKs)
  6. Cyclin-Dependent Kinase 7 (CDK7)

Cyclin-Dependent Kinase 7 (CDK7)

Recombinant Protein Expression Service

Cyclin-Dependent Kinase 7 (CDK7)

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Cat. No. Product Name / Synonyms Species Source
  • HY-P75361
    CDK7&CCNH&MNAT1 Protein, Human (sf9, His)

    CAK1 Protein; CDKN7 Protein; HCAK Protein; MO15 Protein; p39MO15 Protein; STK1 Protein

    		Human Sf9 insect cells
    CDK7, along with regulatory partners CCNH and MNAT1, operates as a crucial serine/threonine kinase in cell cycle regulation and RNA polymerase II-mediated transcription. As the catalytic subunit of the CDK-activating kinase (CAK) complex, CDK7 plays a pivotal role in activating CDK1/cyclin-B and CDK2/cyclins during cell cycle transitions. It phosphorylates key targets, including SPT5/SUPT5H and POLR2A. CDK7, in complex with TFIIH, activates RNA polymerase II for transcript elongation. Its consistent expression and activity contribute to DNA-bound peptide-mediated transcription and cellular growth regulation. CDK7&CCNH&MNAT1 Protein, Human (sf9, His) is the recombinant heterotrimer protein (consiting of CDK7, CCNH, MNAT1), expressed by Sf9 insect cells, with N-His labeled tag. CDK7&CCNH&MNAT1 Protein, Human (sf9, His), has molecular weight of ~25 & 38 & 44 kDa, respectively.
  • HY-P701371
    CDK7-CCNH-MNAT1 Protein, Human (Sf9)

    CDK7; CCNH; MNAT1; Cyclin-dependent kinase 7; 39 kDa protein kinase; p39 Mo15; CDK-activating kinase 1; Cell division protein kinase 7; Serine/threonine-protein kinase 1; TFIIH basal transcription factor complex kinase subunit; Cyclin-H; MO15-associated protein; p34; p37; CDK-activating kinase assembly factor MAT1; CDK7/cyclin-H assembly factor; Cyclin-G1-interacting protein; Menage a trois; RING finger protein 66; RING finger protein MAT1; p35; p36

    		Human Sf9 insect cells
    Together with its regulatory partners CCNH and MNAT1, CDK7 functions as an important serine/threonine kinase in cell cycle regulation and RNA polymerase II-mediated transcription. As the catalytic subunit of the CDK-activated kinase (CAK) complex, CDK7 plays a key role in activating CDK1/cyclin-B and CDK2/cyclin during cell cycle transitions. CDK7-CCNH-MNAT1 Protein, Human (Sf9) is the recombinant human-derived CDK7-CCNH-MNAT1 protein, expressed by Sf9 insect cells , with tag free.
Cat. No. Product Name Effect Purity