POLR1H - RNA polymerase I subunit H Gene

Also Known as TEX6; ZR14; A12.2; HTEX6; Rpa12; ZNRD1; hZR14; HTEX-6; TCTEX6; tctex-6

Species: Homo sapiens

Gene Type: protein coding
Gene ID: 30834

Summary

This gene encodes a DNA-directed RNA polymerase I subunit. The encoded protein contains two potential zinc-binding motifs and may play a role in regulation of cell proliferation. The encoded protein may be involved in Cancer and human immunodeficiency virus progression. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jul 2013]
Ubiquitous expression in lymph node (RPKM 12.3), appendix (RPKM 10.9) and 25 other tissues.

POLR1H Products (4)

mRNA Protein Name
NM_001278785.2 NP_001265714.1 DNA-directed RNA polymerase I subunit RPA12
NM_001278786.2 NP_001265715.1 DNA-directed RNA polymerase I subunit RPA12
NM_014596.6 NP_055411.1 DNA-directed RNA polymerase I subunit RPA12
NM_170783.4 NP_740753.1 DNA-directed RNA polymerase I subunit RPA12

Gene Ontology

  • Molecular Function
  • Cellular Component
Molecular Function GO Annotation Evidence References Source
enables protein binding IPI
IPI: Inferred from physical interaction
32296183 GOA
Cellular Component GO Annotation Evidence References Source
part of RNA polymerase I complex IDA
IDA: Inferred from direct assay
34671025 GOA
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern

POLR1H Protein-protein interaction Information

Type
Protein Name Protein ID Interactor Interactor Species Interactor ID Detection Method References
Intra
POLR1H Q9P1U0 q9y649_human Homo sapiens Q9Y649
Validated Y2H
32814053
Intra
POLR1H Q9P1U0 q9y649_human Homo sapiens Q9Y649
Y2H Array
32814053
Intra
POLR1H Q9P1U0 q9y649_human Homo sapiens Q9Y649
Y2H Pooling
32814053
Intra
POLR1H Q9P1U0 GSN Homo sapiens P06396
Y2H Pooling
32814053
Intra
POLR1H Q9P1U0 GSN Homo sapiens P06396
Validated Y2H
32814053
Intra
POLR1H Q9P1U0 GSN Homo sapiens P06396
Y2H Array
32814053
Cross: Cross-species interaction Intra: Intraspecies interaction