RADIL - Rap associating with DIL domain Gene

Also Known as RASIP2

Species: Homo sapiens

Gene Type: protein coding
Gene ID: 55698

About RADIL

Cytogenetic location: 7p22.1 Genomic coordinates (GRCh38): 7:4,797,055-4,883,716 (from NCBI)

This gene has 7 transcripts (splice variants), 193 orthologues and 1 paralogue. Biased expression in testis (RPKM 4.1), lung (RPKM 1.4) and 10 other tissues.

Summary

Predicted to enable GTPase binding activity. Acts upstream of or within substrate adhesion-dependent cell spreading. Located in microtubule. Part of protein-containing complex. [provided by Alliance of Genome Resources, Apr 2022]

RADIL Products (1)

mRNA Protein Name
NM_018059.5 NP_060529.4 ras-associating and dilute domain-containing protein

Gene Ontology

  • Molecular Function
  • Biological Process
  • Cellular Component
Molecular Function GO Annotation Evidence References Source
enables protein binding IPI
IPI: Inferred from physical interaction
25416956 GOA
Biological Process GO Annotation Evidence References Source
acts upstream of or within substrate adhesion-dependent cell spreading IDA
IDA: Inferred from direct assay
23209302 GOA
Cellular Component GO Annotation Evidence References Source
located in microtubule IDA
IDA: Inferred from direct assay
23209302 GOA
part of protein-containing complex IDA
IDA: Inferred from direct assay
26780829 GOA
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern

RADIL Protein Structure

RA

RA: Ras association (RalGDS/AF-6) domain (62 - 164)

DIL

DIL: DIL domain (635 - 742)

PDZ

PDZ: PDZ domain (Also known as DHR or GLGF) (977 - 1057)

  • 0
  • 200
  • 400
  • 600
  • 800
  • 1000
  • 1075 a.a.
Protein Preferred Names Protein Names

ras-associating and dilute domain-containing protein

  • Rap GTPase interactor

RADIL Protein-protein interaction Information

Type
Protein Name Protein ID Interactor Interactor Species Interactor ID Detection Method References
Intra
RADIL Q96JH8 MAGEA11 Homo sapiens P43364-2
Y2H Prey Pooling
25416956
Intra
RADIL Q96JH8 MAGEA11 Homo sapiens P43364-2
Y2H Array
25416956
Intra
RADIL Q96JH8 MAGEA11 Homo sapiens P43364-2
Validated Y2H
25416956
Intra
RADIL Q96JH8 APOC1 Homo sapiens P02654
Y2H Array
32296183
Intra
RADIL Q96JH8 APOC1 Homo sapiens P02654
Y2H Prey Pooling
32296183
Intra
RADIL Q96JH8 GATA1 Homo sapiens P15976
Y2H Prey Pooling
25416956
Intra
RADIL Q96JH8 CEP76 Homo sapiens Q8TAP6
Y2H Prey Pooling
25416956
Intra
RADIL Q96JH8 CEP76 Homo sapiens Q8TAP6
Y2H Array
25416956
Intra
RADIL Q96JH8 MRFAP1L1 Homo sapiens Q96HT8
Y2H Prey Pooling
25416956
Intra
RADIL Q96JH8 MRFAP1L1 Homo sapiens Q96HT8
Validated Y2H
25416956
Intra
RADIL Q96JH8 KRT31 Homo sapiens Q15323
Y2H Prey Pooling
32296183
Intra
RADIL Q96JH8 KRT31 Homo sapiens Q15323
Y2H Array
32296183
Cross: Cross-species interaction Intra: Intraspecies interaction

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (1)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-RS11615 RADIL Human Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Bos taurus RADIL VGNC VGNC:33691
Rattus norvegicus RADIL RGD RGD:1306155
Macaca mulatta RADIL VGNC VGNC:76520
Felis catus RADIL VGNC VGNC:64481
Mus musculus RADIL MGD MGI:2443088
Others RADIL NCBI