SPACA6 - sperm acrosome associated 6 Gene

Also Known as LET7EH; SPACA6P; LINC00085; NCRNA00085

Species: Homo sapiens

Gene Type: protein coding
Gene ID: 147650

About SPACA6

Cytogenetic location: 19q13.41 Genomic coordinates (GRCh38): 19:51,682,686-51,713,143 (from NCBI)

This gene has 14 transcripts (splice variants) and 82 orthologues. Broad expression in testis (RPKM 2.0), placenta (RPKM 1.7) and 22 other tissues.

Summary

Predicted to be involved in fusion of sperm to egg plasma membrane involved in single fertilization. Predicted to be located in acrosomal vesicle. [provided by Alliance of Genome Resources, Apr 2022]

SPACA6 Products (2)

mRNA Protein Name
NM_001316972.2 NP_001303901.1 sperm acrosome membrane-associated protein 6 isoform 1 precursor
NM_001316994.2 NP_001303923.1 sperm acrosome membrane-associated protein 6 isoform 2

Gene Ontology

  • Molecular Function
Molecular Function GO Annotation Evidence References Source
enables protein binding IPI
IPI: Inferred from physical interaction
25416956 GOA
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

sperm acrosome membrane-associated protein 6

  • BACHELOR-like protein

SPACA6 Protein-protein interaction Information

Type
Protein Name Protein ID Interactor Interactor Species Interactor ID Detection Method References
Intra
SPACA6 W5XKT8 BANP Homo sapiens Q8N9N5
Y2H Array
25416956
Cross: Cross-species interaction Intra: Intraspecies interaction

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (1)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-RS13618 SPACA6 Human Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Felis catus SPACA6 VGNC VGNC:65593
Canis familiaris SPACA6 VGNC VGNC:53990
Mus musculus SPACA6 MGD MGI:1922452
Rattus norvegicus SPACA6 RGD RGD:1588836
Others SPACA6 NCBI