1 Result for "

154313

" in MedChemExpress (MCE) Product Catalog:
Products (1)

1 Results for "154313" in MCE Product Catalog:

Cat. No.: HY-154313
CAS No.: 24527-27-3
Purity:  99.95%
Synonyms: Clospirazine
Target:  

Ras

Research Areas:  

Cancer

Spiclomazine (Clospirazine) is a potent mutant KRAS(G12C) inhibitor that selectively inhibits mutant KRAS-driven pancreatic cancer. Spiclomazine can eliminate KRas-GTP levels in KRAS-driven pancreatic cancer and effectively inhibit RAS-mediated signaling. Spiclomazine significantly inhibits tumor progression in mouse renal capsule xenotransplantation models .
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