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51350

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By Targets:	Drug Derivative (1) Histone Demethylase (2) Leukotriene Receptor (1) MicroRNA (8) PKC (1) Reference Standards (1) Topoisomerase (1)
By Research Areas:	Cancer (11) Cardiovascular Disease (2) Inflammation/Immunology (1)
Oligonucleotides:	miRNA mimics (2) miRNA agomirs (2) miRNA antagomirs (2) MicroRNAs (8) miRNA inhibitors (2)

Inhibitors & Agonists

Antibodies

Oligonucleotides

Cat. No.	Product Name	Target	Research Areas	Chemical Structure

HY-100744

AS8351 1 Publications Verification NSC51355	Histone Demethylase	Cardiovascular Disease
AS8351 (NSC51355) is a KDM5B inhibitor, which can induce and sustain active chromatin marks to facilitate the induction of cardiomyocyte-like cells .

HY-14812

Karenitecin 1 Publications Verification Cositecan; BNP 1350	Topoisomerase	Cancer
Karenitecin (Cositecan) is a topoisomerase I inhibitor, with potent anti-cancer activity.

HY-100173

DW-1350	Leukotriene Receptor	Inflammation/Immunology
DW-1350 is a LTB₄ receptor antagonist.

HY-164428

AE 51310	PKC	Cancer
AE 51310 is an OPN4 inhibitor. AE 51310 inhibits the activation of PKC and the downstream BRAF/MEK/ERKs signaling pathway. AE 51310 can be used for cancer research, such as NSCLC .

HY-R03283

*mmu-miR-5135* mimic**	MicroRNA	Cancer
mmu-miR-5135 mimics are small, chemically synthesized double-stranded RNAs that mimic endogenous miRNAs and enable miRNA functional analysis by up-regulation of miRNA activity.

mmu-miR-5135 mimic mmu-miR-5135 mimic

HY-R03276

*mmu-miR-5130* mimic**	MicroRNA	Cancer
mmu-miR-5130 mimics are small, chemically synthesized double-stranded RNAs that mimic endogenous miRNAs and enable miRNA functional analysis by up-regulation of miRNA activity.

mmu-miR-5130 mimic mmu-miR-5130 mimic

HY-RI03283A

*mmu-miR-5135* antagomir**	MicroRNA	Cancer
mmu-miR-5135 antagomirs are chemically-modified oligonucleotides that hybridize with mature miRNAs. The miRNA antagomirs have 2 phosphorothioates at the 5' end, 4 phosphorothioates at the 3' end, 1 cholesterol group at the 3' end, and full-length nucleotide 2'-methoxy modification. The miRNA antagomirs strongly compete with mature miRNAs to prevent the complementary pairing of miRNAs and their target genes, thereby inhibiting miRNAs from functioning. Stability of miRNA antagomirs appears to be significantly higher than miRNA inhibitors, they exhibits enhanced cellular uptake, stability and regulatory activity in vivo.

mmu-miR-5135 antagomir mmu-miR-5135 antagomir

HY-RI03276A

*mmu-miR-5130* antagomir**	MicroRNA	Cancer
mmu-miR-5130 antagomirs are chemically-modified oligonucleotides that hybridize with mature miRNAs. The miRNA antagomirs have 2 phosphorothioates at the 5' end, 4 phosphorothioates at the 3' end, 1 cholesterol group at the 3' end, and full-length nucleotide 2'-methoxy modification. The miRNA antagomirs strongly compete with mature miRNAs to prevent the complementary pairing of miRNAs and their target genes, thereby inhibiting miRNAs from functioning. Stability of miRNA antagomirs appears to be significantly higher than miRNA inhibitors, they exhibits enhanced cellular uptake, stability and regulatory activity in vivo.

mmu-miR-5130 antagomir mmu-miR-5130 antagomir

HY-RI03283

*mmu-miR-5135* inhibitor**	MicroRNA	Cancer
mmu-miR-5135 inhibitors are chemically-modified oligonucleotides that hybridize with mature miRNAs. The miRNA inhibitors have full-length nucleotide 2'-methoxy modification. The miRNA inhibitors strongly compete with mature miRNAs to prevent the complementary pairing of miRNAs and their target genes, thereby inhibiting miRNAs from functioning.

mmu-miR-5135 inhibitor mmu-miR-5135 inhibitor

HY-R03283A

*mmu-miR-5135* agomir**	MicroRNA	Cancer
mmu-miR-5135 agomirs are chemically-modified double-strand miRNA mimics with modified mature miRNA strand: 2 phosphorothioates at the 5' end, 4 phosphorothioates at the 3' end, 3' end cholesterol group, and full-length nucleotide 2'-methoxy modification. They are designed to mimic endogenous miRNAs and recommended for miRNA functional studies. Compared with miRNA mimics, they exhibits enhanced cellular uptake, stability and regulatory activity in vivo.

mmu-miR-5135 agomir mmu-miR-5135 agomir

HY-RI03276

*mmu-miR-5130* inhibitor**	MicroRNA	Cancer
mmu-miR-5130 inhibitors are chemically-modified oligonucleotides that hybridize with mature miRNAs. The miRNA inhibitors have full-length nucleotide 2'-methoxy modification. The miRNA inhibitors strongly compete with mature miRNAs to prevent the complementary pairing of miRNAs and their target genes, thereby inhibiting miRNAs from functioning.

mmu-miR-5130 inhibitor mmu-miR-5130 inhibitor

HY-R03276A

*mmu-miR-5130* agomir**	MicroRNA	Cancer
mmu-miR-5130 agomirs are chemically-modified double-strand miRNA mimics with modified mature miRNA strand: 2 phosphorothioates at the 5' end, 4 phosphorothioates at the 3' end, 3' end cholesterol group, and full-length nucleotide 2'-methoxy modification. They are designed to mimic endogenous miRNAs and recommended for miRNA functional studies. Compared with miRNA mimics, they exhibits enhanced cellular uptake, stability and regulatory activity in vivo.

mmu-miR-5130 agomir mmu-miR-5130 agomir

HY-100744R

AS8351 (Standard) NSC51355 (Standard)	Histone Demethylase Reference Standards	Cardiovascular Disease
AS8351 (Standard) is the analytical standard of AS8351 (HY-100744). This product is intended for research and analytical applications. AS8351 (NSC51355) is a KDM5B inhibitor, which can induce and sustain active chromatin marks to facilitate the induction of cardiomyocyte-like cells .

HY-160829

Karenitecin-NH2 Cositecan-NH2; BNP 1350-NH2	Drug Derivative	Cancer
Karenitecin-NH2 (Cositecan-NH2) (DB-173) is a Camptothecin (HY-16560) analogue with antitumor activity .

Host:	Mouse (3) Rabbit (2)
Reactivity:	Human (5) Rat (4) Mouse (5) Dog (1)
Application:	IHC-P (3) ICC/IF (2) IF-Tissue (1) IHC-F (1) WB (4) FC (3)
Isotype:	IgG (2) IgG1 (1)
Conjugation:	Non-conjugated (5)
Clonality:	Monoclonal (5)
Modification:	Unmodified (5)

Cat. No.	Compare	Product Name	Application	Reactivity	Image

HY-P85658

	Kif 7 Antibody (YA5350) Kinesin-like protein KIF7	IHC-P, ICC/IF	Human, Mouse, Rat
	Kif 7 Antibody (YA5350) is a Mouse-derived and non-conjugated monoclonal antibody, targeting to Kif 7.

HY-P85443

	L1CAM Antibody (YA5135) L1CAM; CAML1; MIC5; Neural cell adhesion molecule L1; N-CAM-L1; NCAM-L1; CD antigen CD171	WB, FC	Human, Mouse, Rat
	L1CAM Antibody (YA5135) is a Mouse-derived and non-conjugated monoclonal antibody, targeting to L1CAM.

HY-P85438

	Ikaros Antibody (YA5130) IKZF1; IK1; IKAROS; LYF1; ZNFN1A1; DNA-binding protein Ikaros; Ikaros family zinc finger protein 1; Lymphoid transcription factor LyF-1	WB	Human, Mouse, Dog
	Ikaros Antibody (YA5130) is a Mouse-derived and non-conjugated monoclonal antibody, targeting to Ikaros.

HY-P85458

	Protein Phosphatase 4C Antibody (YA5150) PPP4C; PPP4; PPX; Serine/threonine-protein phosphatase 4 catalytic subunit; PP4C; Pp4; Protein phosphatase X; PP-X	WB, IHC-P, FC	Human, Mouse, Rat
	Protein Phosphatase 4C Antibody (YA5150) is a Rabbit-derived and non-conjugated monoclonal antibody, targeting to Protein Phosphatase 4C.

HY-P86665

	Sodium Potassium ATPase Antibody (YA6357) ATP1A1; alpha 1 Sodium Potassium ATPase; A1A1; AT1A1; AT1A1_HUMAN; Atpa-1; ATPase Na+/K+transporting alpha 1 polypeptide; ATPase Na+/K+transporting subunit alpha 1; BC010319; EC 3.6.3.9; MGC3285; MGC38419; MGC51750; Na K ATPase alpha A catalytic polypeptide; Na K ATPase catalytic subunit alpha A protein; Na(+)/K(+) ATPase 1; Na(+)/K(+) ATPase alpha-1 subunit; Na+, K+ATPase alpha subunit; Na+/K+ATPase alpha 1 subunit; Na+/K+ATPase 1; Na, K ATPase alpha 1 subunit; Nkaa1b; Sodium potassium ATPase alpha 1 polypeptide; Sodium pump 1; Sodium pump subunit alpha-1; sodium-potassium ATPase catalytic subunit alpha-1; Sodium/potassium-transporting ATPase subunit alpha-1.	WB, IHC-P, IHC-F, ICC/IF, IF-Tissue, FC	Human, Mouse, Rat
	Sodium Potassium ATPase Antibody (YA6357) is a Rabbit-derived and non-conjugated IgG monoclonal antibody, targeting to Sodium Potassium ATPase.

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Cat. No.	Product Name		Classification

HY-R03283

*mmu-miR-5135* mimic**		MicroRNAs miRNA mimics
mmu-miR-5135 mimics are small, chemically synthesized double-stranded RNAs that mimic endogenous miRNAs and enable miRNA functional analysis by up-regulation of miRNA activity.

HY-R03276

*mmu-miR-5130* mimic**		MicroRNAs miRNA mimics
mmu-miR-5130 mimics are small, chemically synthesized double-stranded RNAs that mimic endogenous miRNAs and enable miRNA functional analysis by up-regulation of miRNA activity.

HY-RI03283A

*mmu-miR-5135* antagomir**		MicroRNAs miRNA antagomirs
mmu-miR-5135 antagomirs are chemically-modified oligonucleotides that hybridize with mature miRNAs. The miRNA antagomirs have 2 phosphorothioates at the 5' end, 4 phosphorothioates at the 3' end, 1 cholesterol group at the 3' end, and full-length nucleotide 2'-methoxy modification. The miRNA antagomirs strongly compete with mature miRNAs to prevent the complementary pairing of miRNAs and their target genes, thereby inhibiting miRNAs from functioning. Stability of miRNA antagomirs appears to be significantly higher than miRNA inhibitors, they exhibits enhanced cellular uptake, stability and regulatory activity in vivo.

HY-RI03276A

*mmu-miR-5130* antagomir**		MicroRNAs miRNA antagomirs
mmu-miR-5130 antagomirs are chemically-modified oligonucleotides that hybridize with mature miRNAs. The miRNA antagomirs have 2 phosphorothioates at the 5' end, 4 phosphorothioates at the 3' end, 1 cholesterol group at the 3' end, and full-length nucleotide 2'-methoxy modification. The miRNA antagomirs strongly compete with mature miRNAs to prevent the complementary pairing of miRNAs and their target genes, thereby inhibiting miRNAs from functioning. Stability of miRNA antagomirs appears to be significantly higher than miRNA inhibitors, they exhibits enhanced cellular uptake, stability and regulatory activity in vivo.

HY-RI03283

*mmu-miR-5135* inhibitor**		MicroRNAs miRNA inhibitors
mmu-miR-5135 inhibitors are chemically-modified oligonucleotides that hybridize with mature miRNAs. The miRNA inhibitors have full-length nucleotide 2'-methoxy modification. The miRNA inhibitors strongly compete with mature miRNAs to prevent the complementary pairing of miRNAs and their target genes, thereby inhibiting miRNAs from functioning.

HY-R03283A

*mmu-miR-5135* agomir**		MicroRNAs miRNA agomirs
mmu-miR-5135 agomirs are chemically-modified double-strand miRNA mimics with modified mature miRNA strand: 2 phosphorothioates at the 5' end, 4 phosphorothioates at the 3' end, 3' end cholesterol group, and full-length nucleotide 2'-methoxy modification. They are designed to mimic endogenous miRNAs and recommended for miRNA functional studies. Compared with miRNA mimics, they exhibits enhanced cellular uptake, stability and regulatory activity in vivo.

HY-RI03276

*mmu-miR-5130* inhibitor**		MicroRNAs miRNA inhibitors
mmu-miR-5130 inhibitors are chemically-modified oligonucleotides that hybridize with mature miRNAs. The miRNA inhibitors have full-length nucleotide 2'-methoxy modification. The miRNA inhibitors strongly compete with mature miRNAs to prevent the complementary pairing of miRNAs and their target genes, thereby inhibiting miRNAs from functioning.

HY-R03276A

*mmu-miR-5130* agomir**		MicroRNAs miRNA agomirs
mmu-miR-5130 agomirs are chemically-modified double-strand miRNA mimics with modified mature miRNA strand: 2 phosphorothioates at the 5' end, 4 phosphorothioates at the 3' end, 3' end cholesterol group, and full-length nucleotide 2'-methoxy modification. They are designed to mimic endogenous miRNAs and recommended for miRNA functional studies. Compared with miRNA mimics, they exhibits enhanced cellular uptake, stability and regulatory activity in vivo.

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