TSGA10 - testis specific 10 Gene

Also Known as CT79; CEP4L; SPGF26

Species: Homo sapiens

Gene Type: protein coding
Gene ID: 80705

About TSGA10

Cytogenetic location: 2q11.2 Genomic coordinates (GRCh38): 2:98,997,261-99,154,966 (from NCBI)

This gene has 19 transcripts (splice variants), 157 orthologues, 4 paralogues and is associated with 1 phenotype. Biased expression in testis (RPKM 16.6) and thyroid (RPKM 1.5).

Summary

Predicted to enable structural molecule activity. Predicted to be involved in spermatogenesis. Predicted to act upstream of or within cell projection assembly. Predicted to be located in neuron projection; sperm fibrous sheath; and sperm principal piece. Implicated in spermatogenic failure 26. [provided by Alliance of Genome Resources, Apr 2022]

TSGA10 Products (5)

mRNA Protein Name
NM_001349012.1 NP_001335941.1 testis-specific gene 10 protein isoform 1
NM_001349013.2 NP_001335942.1 testis-specific gene 10 protein isoform 2
NM_001349014.1 NP_001335943.1 testis-specific gene 10 protein isoform 2
NM_025244.4 NP_079520.1 testis-specific gene 10 protein isoform 1
NM_182911.4 NP_878915.2 testis-specific gene 10 protein isoform 1

Gene Ontology

  • Molecular Function
Molecular Function GO Annotation Evidence References Source
enables protein binding IPI
IPI: Inferred from physical interaction
21516116 GOA
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

testis-specific gene 10 protein

  • cancer/testis antigen 79

TSGA10 Protein-protein interaction Information

Type
Protein Name Protein ID Interactor Interactor Species Interactor ID Detection Method References
Intra
TSGA10 Q9BZW7 MID2 Homo sapiens Q9UJV3-2
Validated Y2H
25416956
Intra
TSGA10 Q9BZW7 MID2 Homo sapiens Q9UJV3-2
Y2H Array
25416956
Intra
TSGA10 Q9BZW7 BCL6B Homo sapiens A8KA13
Validated Y2H
25416956
Intra
TSGA10 Q9BZW7 BCL6B Homo sapiens A8KA13
Y2H Prey Pooling
25416956
Intra
TSGA10 Q9BZW7 CCHCR1 Homo sapiens Q8TD31-3
Y2H Prey Pooling
25416956
Intra
TSGA10 Q9BZW7 CCHCR1 Homo sapiens Q8TD31-3
Y2H Prey Pooling
32296183
Intra
TSGA10 Q9BZW7 CCHCR1 Homo sapiens Q8TD31-3
Y2H Array
32296183
Intra
TSGA10 Q9BZW7 FLJ38668 Homo sapiens C0H5X2
Validated Y2H
25416956
Intra
TSGA10 Q9BZW7 FLJ38668 Homo sapiens C0H5X2
Y2H Array
25416956
Intra
TSGA10 Q9BZW7 CEP57L1 Homo sapiens Q8IYX8-2
Y2H Prey Pooling
25416956
Intra
TSGA10 Q9BZW7 CEP57L1 Homo sapiens Q8IYX8-2
Validated Y2H
25416956
Intra
TSGA10 Q9BZW7 CREB5 Homo sapiens Q02930-3
Y2H Array
25416956
Intra
TSGA10 Q9BZW7 RTP5 Homo sapiens Q14D33
Y2H Prey Pooling
25416956
Intra
TSGA10 Q9BZW7 RTP5 Homo sapiens Q14D33
Validated Y2H
25416956
Intra
TSGA10 Q9BZW7 RTP5 Homo sapiens Q14D33
Y2H Array
25416956
Intra
TSGA10 Q9BZW7 FBF1 Homo sapiens Q8TES7-6
Y2H Prey Pooling
25416956
Intra
TSGA10 Q9BZW7 FBF1 Homo sapiens Q8TES7-6
Validated Y2H
25416956
Intra
TSGA10 Q9BZW7 SYT6 Homo sapiens Q5T7P8-2
Validated Y2H
25416956
Intra
TSGA10 Q9BZW7 ZNF2 Homo sapiens Q9BSG1-2
Y2H Prey Pooling
25416956
Intra
TSGA10 Q9BZW7 ZNF2 Homo sapiens Q9BSG1-2
Validated Y2H
25416956
Intra
TSGA10 Q9BZW7 HDX Homo sapiens Q7Z353
Y2H Prey Pooling
32296183
Intra
TSGA10 Q9BZW7 HDX Homo sapiens Q7Z353
Y2H Array
32296183
Intra
TSGA10 Q9BZW7 HOOK2 Homo sapiens Q96ED9-2
Y2H Prey Pooling
32296183
Intra
TSGA10 Q9BZW7 HOOK2 Homo sapiens Q96ED9-2
Y2H Array
32296183
Intra
TSGA10 Q9BZW7 PPP1R13B Homo sapiens Q96KQ4
Y2H Array
32296183
Intra
TSGA10 Q9BZW7 PPP1R13B Homo sapiens Q96KQ4
Y2H Prey Pooling
32296183
Intra
TSGA10 Q9BZW7 ZNF490 Homo sapiens Q9ULM2
Validated Y2H
25416956
Intra
TSGA10 Q9BZW7 PRDM6 Homo sapiens Q9NQX0
Y2H Prey Pooling
32296183
Intra
TSGA10 Q9BZW7 PRDM6 Homo sapiens Q9NQX0
Validated Y2H
32296183
Intra
TSGA10 Q9BZW7 PRDM6 Homo sapiens Q9NQX0
Y2H Array
32296183
Intra
TSGA10 Q9BZW7 CEP57 Homo sapiens Q86XR8-3
Y2H Prey Pooling
32296183
Intra
TSGA10 Q9BZW7 CEP57 Homo sapiens Q86XR8-3
Y2H Array
32296183
Intra
TSGA10 Q9BZW7 TP53BP2 Homo sapiens Q05BL1
Y2H Array
32296183
Intra
TSGA10 Q9BZW7 TP53BP2 Homo sapiens Q05BL1
Y2H Prey Pooling
32296183
Intra
TSGA10 Q9BZW7 DISC1 Homo sapiens Q9NRI5-2
Y2H Prey Pooling
32296183
Intra
TSGA10 Q9BZW7 DISC1 Homo sapiens Q9NRI5-2
Y2H Array
32296183
Intra
TSGA10 Q9BZW7 DISC1 Homo sapiens Q9NRI5-2
Validated Y2H
32296183
Intra
TSGA10 Q9BZW7 PLEKHA7 Homo sapiens Q6IQ23-2
Y2H Prey Pooling
32296183
Intra
TSGA10 Q9BZW7 PLEKHA7 Homo sapiens Q6IQ23-2
Y2H Array
32296183
Intra
TSGA10 Q9BZW7 RBAK Homo sapiens Q9NYW8
Validated Y2H
32296183
Intra
TSGA10 Q9BZW7 RBAK Homo sapiens Q9NYW8
Y2H Prey Pooling
32296183
Intra
TSGA10 Q9BZW7 RBAK Homo sapiens Q9NYW8
Y2H Array
32296183
Intra
TSGA10 Q9BZW7 LZTS1 Homo sapiens Q9Y250
Y2H Prey Pooling
32296183
Intra
TSGA10 Q9BZW7 LZTS1 Homo sapiens Q9Y250
Validated Y2H
32296183
Intra
TSGA10 Q9BZW7 LZTS1 Homo sapiens Q9Y250
Y2H Array
32296183
Intra
TSGA10 Q9BZW7 MBD3L1 Homo sapiens Q8WWY6
Y2H Prey Pooling
32296183
Intra
TSGA10 Q9BZW7 MBD3L1 Homo sapiens Q8WWY6
Y2H Array
32296183
Intra
TSGA10 Q9BZW7 PIBF1 Homo sapiens Q4G0R1
Y2H Array
32296183
Intra
TSGA10 Q9BZW7 PIBF1 Homo sapiens Q4G0R1
Y2H Prey Pooling
32296183
Intra
TSGA10 Q9BZW7 PRPF31 Homo sapiens Q8WWY3
Validated Y2H
25416956
Intra
TSGA10 Q9BZW7 PRPF31 Homo sapiens Q8WWY3
Y2H Array
25416956
Intra
TSGA10 Q9BZW7 JRK Homo sapiens O75564-2
Y2H Array
32296183
Intra
TSGA10 Q9BZW7 JRK Homo sapiens O75564-2
Y2H Prey Pooling
32296183
Intra
TSGA10 Q9BZW7 a0a1u9x8x8_human Homo sapiens A0A1U9X8X8
Y2H Array
32296183
Intra
TSGA10 Q9BZW7 a0a1u9x8x8_human Homo sapiens A0A1U9X8X8
Y2H Prey Pooling
32296183
Intra
TSGA10 Q9BZW7 ZNF124 Homo sapiens Q15973
Y2H Array
25416956
Intra
TSGA10 Q9BZW7 ZNF124 Homo sapiens Q15973
Validated Y2H
25416956
Intra
TSGA10 Q9BZW7 KANK2 Homo sapiens Q63ZY3
Y2H Prey Pooling
32296183
Intra
TSGA10 Q9BZW7 KANK2 Homo sapiens Q63ZY3
Y2H Array
32296183
Intra
TSGA10 Q9BZW7 PPP1R18 Homo sapiens Q6NYC8
Y2H Prey Pooling
25416956
Intra
TSGA10 Q9BZW7 TRIM14 Homo sapiens Q14142
Y2H Prey Pooling
32296183
Intra
TSGA10 Q9BZW7 TRIM14 Homo sapiens Q14142
Y2H Array
32296183
Intra
TSGA10 Q9BZW7 ZNF544 Homo sapiens Q6NX49
Y2H Array
25416956
Intra
TSGA10 Q9BZW7 ZNF544 Homo sapiens Q6NX49
Y2H Prey Pooling
25416956
Intra
TSGA10 Q9BZW7 KRT76 Homo sapiens Q01546
Y2H Array
32296183
Intra
TSGA10 Q9BZW7 KRT76 Homo sapiens Q01546
Y2H Prey Pooling
32296183
Intra
TSGA10 Q9BZW7 KIAA1328 Homo sapiens Q86T90
Y2H Array
32296183
Intra
TSGA10 Q9BZW7 KIAA1328 Homo sapiens Q86T90
Y2H Prey Pooling
32296183
Intra
TSGA10 Q9BZW7 CCDC88B Homo sapiens A6NC98
Y2H Array
32296183
Intra
TSGA10 Q9BZW7 CCDC88B Homo sapiens A6NC98
Y2H Prey Pooling
32296183
Intra
TSGA10 Q9BZW7 MATR3 Homo sapiens P43243
Y2H Prey Pooling
32296183
Intra
TSGA10 Q9BZW7 MATR3 Homo sapiens P43243
Y2H Array
32296183
Intra
TSGA10 Q9BZW7 COG6 Homo sapiens Q9Y2V7
Validated Y2H
32296183
Intra
TSGA10 Q9BZW7 COG6 Homo sapiens Q9Y2V7
Y2H Array
32296183
Intra
TSGA10 Q9BZW7 COG6 Homo sapiens Q9Y2V7
Y2H Prey Pooling
32296183
Intra
TSGA10 Q9BZW7 ZBTB26 Homo sapiens Q9HCK0
Validated Y2H
32296183
Intra
TSGA10 Q9BZW7 ZBTB26 Homo sapiens Q9HCK0
Y2H Array
32296183
Intra
TSGA10 Q9BZW7 ZBTB26 Homo sapiens Q9HCK0
Y2H Prey Pooling
32296183
Intra
TSGA10 Q9BZW7 PRDM14 Homo sapiens Q9GZV8
Y2H Prey Pooling
32296183
Intra
TSGA10 Q9BZW7 PRDM14 Homo sapiens Q9GZV8
Validated Y2H
32296183
Intra
TSGA10 Q9BZW7 PRDM14 Homo sapiens Q9GZV8
Y2H Array
32296183
Intra
TSGA10 Q9BZW7 AXIN2 Homo sapiens Q9Y2T1
Validated Y2H
32296183
Intra
TSGA10 Q9BZW7 AXIN2 Homo sapiens Q9Y2T1
Y2H Array
32296183
Intra
TSGA10 Q9BZW7 AXIN2 Homo sapiens Q9Y2T1
Y2H Prey Pooling
32296183
Intra
TSGA10 Q9BZW7 PPHLN1 Homo sapiens Q8NEY8
Y2H Array
25416956
Intra
TSGA10 Q9BZW7 HNRNPM Homo sapiens P52272
Y2H Array
32296183
Intra
TSGA10 Q9BZW7 HNRNPM Homo sapiens P52272
Y2H Prey Pooling
32296183
Intra
TSGA10 Q9BZW7 BIRC2 Homo sapiens Q13490
Validated Y2H
25416956
Intra
TSGA10 Q9BZW7 BIRC2 Homo sapiens Q13490
Y2H Prey Pooling
25416956
Intra
TSGA10 Q9BZW7 GOLGA2 Homo sapiens Q08379
Y2H Array
32296183
Intra
TSGA10 Q9BZW7 GOLGA2 Homo sapiens Q08379
Y2H Prey Pooling
32296183
Intra
TSGA10 Q9BZW7 ZNF587 Homo sapiens Q96SQ5
Y2H Prey Pooling
25416956
Intra
TSGA10 Q9BZW7 ZNF587 Homo sapiens Q96SQ5
Validated Y2H
25416956
Intra
TSGA10 Q9BZW7 ZNF587 Homo sapiens Q96SQ5
Y2H Array
25416956
Intra
TSGA10 Q9BZW7 TCEA2 Homo sapiens Q15560
Y2H Array
25416956
Intra
TSGA10 Q9BZW7 CBX8 Homo sapiens Q9HC52
Validated Y2H
25416956
Intra
TSGA10 Q9BZW7 CBX8 Homo sapiens Q9HC52
Y2H Array
25416956
Intra
TSGA10 Q9BZW7 TLE5 Homo sapiens Q08117
Validated Y2H
25416956
Intra
TSGA10 Q9BZW7 ZNF410 Homo sapiens Q86VK4
Y2H Array
25416956
Intra
TSGA10 Q9BZW7 ZNF417 Homo sapiens Q8TAU3
Y2H Prey Pooling
25416956
Intra
TSGA10 Q9BZW7 SORBS3 Homo sapiens O60504
Y2H Prey Pooling
32296183
Intra
TSGA10 Q9BZW7 SORBS3 Homo sapiens O60504
Y2H Array
32296183
Intra
TSGA10 Q9BZW7 CBY2 Homo sapiens Q8NA61
Y2H Prey Pooling
25416956
Intra
TSGA10 Q9BZW7 PAK5 Homo sapiens Q9P286
Y2H Array
32296183
Intra
TSGA10 Q9BZW7 PAK5 Homo sapiens Q9P286
Y2H Prey Pooling
32296183
Intra
TSGA10 Q9BZW7 PAK5 Homo sapiens Q9P286
Validated Y2H
32296183
Intra
TSGA10 Q9BZW7 MAD1L1 Homo sapiens Q9Y6D9
Validated Y2H
32296183
Intra
TSGA10 Q9BZW7 MAD1L1 Homo sapiens Q9Y6D9
Y2H Array
32296183
Intra
TSGA10 Q9BZW7 MAD1L1 Homo sapiens Q9Y6D9
Y2H Prey Pooling
32296183
Intra
TSGA10 Q9BZW7 ZNF426 Homo sapiens Q9BUY5
Y2H Prey Pooling
25416956
Intra
TSGA10 Q9BZW7 ZNF426 Homo sapiens Q9BUY5
Y2H Array
25416956
Intra
TSGA10 Q9BZW7 RCOR3 Homo sapiens Q9P2K3
Validated Y2H
25416956
Intra
TSGA10 Q9BZW7 RCOR3 Homo sapiens Q9P2K3
Y2H Array
25416956
Intra
TSGA10 Q9BZW7 CEP44 Homo sapiens Q9C0F1
Y2H Prey Pooling
25416956
Intra
TSGA10 Q9BZW7 CEP44 Homo sapiens Q9C0F1
Validated Y2H
25416956
Intra
TSGA10 Q9BZW7 CEP44 Homo sapiens Q9C0F1
Y2H Prey Pooling
32296183
Intra
TSGA10 Q9BZW7 CEP44 Homo sapiens Q9C0F1
Validated Y2H
32296183
Intra
TSGA10 Q9BZW7 CEP44 Homo sapiens Q9C0F1
Y2H Array
25416956
Intra
TSGA10 Q9BZW7 CEP44 Homo sapiens Q9C0F1
Y2H Array
32296183
Intra
TSGA10 Q9BZW7 ZBTB24 Homo sapiens O43167
Validated Y2H
25416956
Intra
TSGA10 Q9BZW7 ZNF670 Homo sapiens Q9BS34
Y2H Array
25416956
Intra
TSGA10 Q9BZW7 ZNF670 Homo sapiens Q9BS34
Y2H Prey Pooling
25416956
Intra
TSGA10 Q9BZW7 CDK18 Homo sapiens Q07002
Validated Y2H
25416956
Intra
TSGA10 Q9BZW7 CDK18 Homo sapiens Q07002
Y2H Array
25416956
Intra
TSGA10 Q9BZW7 CDK18 Homo sapiens Q07002
Y2H Prey Pooling
25416956
Intra
TSGA10 Q9BZW7 NAB2 Homo sapiens Q15742
Y2H Prey Pooling
32296183
Intra
TSGA10 Q9BZW7 NAB2 Homo sapiens Q15742
Y2H Array
32296183
Intra
TSGA10 Q9BZW7 ZNF599 Homo sapiens Q96NL3
Validated Y2H
25416956
Intra
TSGA10 Q9BZW7 ZNF599 Homo sapiens Q96NL3
Y2H Prey Pooling
25416956
Intra
TSGA10 Q9BZW7 ZNF599 Homo sapiens Q96NL3
Y2H Array
25416956
Intra
TSGA10 Q9BZW7 CDC73 Homo sapiens Q6P1J9
Y2H Prey Pooling
25416956
Intra
TSGA10 Q9BZW7 CDC73 Homo sapiens Q6P1J9
Validated Y2H
25416956
Intra
TSGA10 Q9BZW7 CDC73 Homo sapiens Q6P1J9
Y2H Array
25416956
Intra
TSGA10 Q9BZW7 ZBTB39 Homo sapiens O15060
Y2H Array
32296183
Intra
TSGA10 Q9BZW7 ZBTB39 Homo sapiens O15060
Y2H Prey Pooling
32296183
Cross: Cross-species interaction Intra: Intraspecies interaction

Related Diseases

Diseases Alias
Spermatogenic Failure 26

  • SPGF26
Spermatogenic Failure

  • Azoospermia

  • Spgf

  • Spermatogenic Failure, Susceptibility To

  • Absent Sperm

  • Aspermatogenesis

  • Infertility Due To Azoospermia

  • Hypospermatogenesis

  • Azoospermatism
Spermatogenic Failure 16

  • SPGF16

  • Acephalic Spermatozoa Syndrome

  • Spermatozoa, Acephalic
Male Infertility Due To Acephalic Spermatozoa

  • Acephalic Spermatozoa Syndrome
Parapsoriasis

  • Digitate Dermatosis

  • Parapsoriasis En Plaque

  • Parapsoriasis En Plaques
Gemistocytic Astrocytoma

  • Gemistocytic Astrocytic Tumor
Diseases Alias
Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (3)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-RS15143 TSGA10 Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS21966 Tsga10 Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS28483 Tsga10 Rat Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Canis familiaris TSGA10 VGNC VGNC:47899
Mus musculus TSGA10 MGD MGI:2685063
Rattus norvegicus TSGA10 RGD RGD:621142
Felis catus TSGA10 VGNC VGNC:66614
Bos taurus TSGA10 VGNC VGNC:36415
Macaca mulatta TSGA10 VGNC VGNC:106243
Others TSGA10 NCBI