7 Results for "

147687

" in MedChemExpress (MCE) Product Catalog:
Products (7)

7 Results for "147687" in MCE Product Catalog:

6
Atrasentan
Atrasentan
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6 Publications Verification
Cat. No.: HY-15403
CAS No.: 173937-91-2
Purity:  99.58%
Synonyms: ABT-627; (+)-A 127722; A-147627
Target:  

Endothelin Receptor

Research Areas:  

Cardiovascular Disease Endocrinology Cancer

Atrasentan (ABT-627) is an endothelin receptor antagonist with IC50 of 0.0551 nM for ETA .
6
Atrasentan hydrochloride
Atrasentan hydrochloride
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6 Publications Verification
Cat. No.: HY-15403A
CAS No.: 195733-43-8
Purity:  99.82%
Synonyms: ABT-627 hydrochloride; (+)-A 127722 hydrochloride; A-147627 hydrochloride
Target:  

Endothelin Receptor

Research Areas:  

Cardiovascular Disease Endocrinology Cancer

Atrasentan hydrochloride (ABT-627 hydrochloride) is a selective endothelin A receptor antagonist with an IC50 of 0.0551 nM for ETA .
2
Dapivirine
Dapivirine
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2 Cited Publications
Cat. No.: HY-14266
CAS No.: 244767-67-7
Purity:  99.80%
Synonyms: TMC120; R147681
Target:  

HIV Reverse Transcriptase Apoptosis Autophagy

Research Areas:  

Infection

Dapivirine (TMC120), the prototype of diarylpyrimidines (DAPY), is an orally active and nonnucleoside reverse transcriptase inhibitor (NRTI). Dapivirine (TMC120) binds directly to HIV-1 reverse transcriptase. Dapivirine (TMC120) regulates autophagy and induced Akt, Bad and SAPK/JNK activations .
Dapivirine (Standard)
Dapivirine (Standard)
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Cat. No.: HY-14266R
CAS No.: 244767-67-7
Synonyms: TMC120 (Standard); R147681 (Standard)
Target:  

HIV Reverse Transcriptase Apoptosis Autophagy Reference Standards

Research Areas:  

Infection

Dapivirine (Standard) is the analytical standard of Dapivirine. This product is intended for research and analytical applications. Dapivirine (TMC120), the prototype of diarylpyrimidines (DAPY), is an orally active and nonnucleoside reverse transcriptase inhibitor (NRTI). Dapivirine (TMC120) binds directly to HIV-1 reverse transcriptase. Dapivirine (TMC120) regulates autophagy and induced Akt, Bad and SAPK/JNK activations .
FR-146687
FR-146687
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Cat. No.: HY-19284
CAS No.: 146939-64-2
Synonyms: FK 687; TF 505
Target:  

5 alpha Reductase

Research Areas:  

Endocrinology

FR-146687 (FK 687) is a selective and orally active 5α-reductase inhibitor with IC50s of 1.7 nM and 4.6 nM for rat and human 5α-reductases, respectively. FR-146687 shows no inhibitory effects on other steroid oxidoreductases .
Dapivirine-d11
Dapivirine-d11
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Cat. No.: HY-14266S
CAS No.: 1329613-10-6
Synonyms: TMC120-d11; R147681-d11
Dapivirine-d11 is the deuterium labeled Dapivirine. Dapivirine (TMC120), the prototype of diarylpyrimidines (DAPY), is an orally active and nonnucleoside reverse transcriptase inhibitor (NRTI). Dapivirine (TMC120) binds directly to HIV-1 reverse transcriptase. Dapivirine (TMC120) regulates autophagy and induced Akt, Bad and SAPK/JNK activations .
Dapivirine-d4
Dapivirine-d4
0 Images
Cat. No.: HY-14266S1
CAS No.: 1309283-15-5
Synonyms: TMC120-d4; R147681-d4
Dapivirine-d4 (TMC120-d4) is deuterium labeled Dapivirine. Dapivirine (TMC120), the prototype of diarylpyrimidines (DAPY), is an orally active and nonnucleoside reverse transcriptase inhibitor (NRTI). Dapivirine (TMC120) binds directly to HIV-1 reverse transcriptase. Dapivirine (TMC120) regulates autophagy and induced Akt, Bad and SAPK/JNK activations .
Assay Types