2. Gene
  3. RUNDC3A - RUN domain containing 3A Gene

RUNDC3A - RUN domain containing 3A Gene

  • Gene
  • Protein
  • Disease
  • Agent
  • Ortholog
Homo sapiens

Also known as RPIP8; RAP2IP; RPIP-8

Gene ID: 10900 | Gene type: protein coding

About RUNDC3A

Cytogenetic location: 17q21.31 Genomic coordinates (GRCh38): 17:44,308,601-44,318,670 (from NCBI)

This gene has 7 transcripts (splice variants), 267 orthologues and 13 paralogues. Biased expression in brain (RPKM 51.0), adrenal (RPKM 6.3) and 1 other tissue.

Summary

Predicted to enable GTPase regulator activity. Predicted to be involved in positive regulation of cGMP-mediated signaling. Located in intracellular membrane-bounded organelle. [provided by Alliance of Genome Resources, Apr 2022]

RUNDC3A Products(3)

mRNA Protein Name
NM_001144825.2 NP_001138297.1 RUN domain-containing protein 3A isoform 1
NM_001144826.2 NP_001138298.1 RUN domain-containing protein 3A isoform 3
NM_006695.5 NP_006686.1 RUN domain-containing protein 3A isoform 2

RUNDC3A Protein Structure

RUN

RUN: RUN domain (60 - 187)

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  • 446 a.a.
Protein Preferred Names Protein Names

RUN domain-containing protein 3A

RaP2 interacting protein 8

Related Diseases

Diseases Alias
Malignant Pineal Area Germ Cell Neoplasm

Pineal Germ Cell Tumor

Malignant Pineal Parenchymal Germ Cell Tumor

Pineal Region Germ Cell Tumor

Pineal Cell Tumor

Pineal Cell Tumour

Pineal Region Germinoma

Malignant Pineal Region Germ Cell Tumor

Pineal Germinoma
Diseases Alias
Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Related Agents

Pre-clinical Phase
Bioactive Molecules (1)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-RS12348 RUNDC3A Human Pre-designed siRNA Set A / Unkown

Orthologs Information

Species Symbol Source ID
Rattus norvegicus RUNDC3A RGD RGD:735057
Macaca mulatta RUNDC3A VGNC VGNC:77032
Bos taurus RUNDC3A VGNC VGNC:34218
Mus musculus RUNDC3A MGD MGI:1858752
Canis familiaris RUNDC3A VGNC VGNC:45807
Felis catus RUNDC3A VGNC VGNC:64822